The medicine “Fungoterbin” is a popular antifungal drug in a convenient pharmacological form (spray). In the article, we will consider detailed instructions for use with this drug, talk about analogues and study reviews.
Composition and packaging of medication
Spray "Fungoterbin" for local use is made in the form of a clear liquid, the main active compound of which is terbinafine hydrochloride.
In addition to it, the medicine contains some additional substances, which include:
- carbamide (urea);
- dibunol (butylhydroxytoluene);
- povidone (polyvinylpyrrolidone);
- ethanol 95%;
- propylene glycol.
This medicinal spray is packaged in polymer bottles with a dispenser, 30 and 15 ml. Packaging - cardboard boxes.
Pharmacological properties of this drug
Spray "Fungoterbin" is an antifungal medication for external use from the category of allylamines, which has an extensive spectrum of antifungal effects. Terbinafine, which acts as an active substance in a drug, disrupts the biological synthesis of ergosterol in fungi at an early stage. This leads to a lack of ergosterol and to the accumulation of squalene inside the cells, which provokes the death of pathogenic fungi. The action of terbinafine is carried out by inhibiting an enzyme such as squalene epoxidase, which is located on the cell membranes of fungi. This enzyme is not related to the cytochrome P450 system.
The basic substance in small concentrations is capable of exerting a fungicidal effect on dermatophytes (including Epidermophyton floccosum, Trychophyton mentagrophytes, Trychophyton rubrum, Trychophyton verrucosum, Trychophyton tonsurans, Trychophyton violaceum, Microsporum canis), mold (in particular, Candida albicans) Pityrosporum orbiculare), provoking the onset of their death. Functionality with respect to yeast-like fungi, depending on their variety, may be fungistatic or fungicidal.
Urea, which is also present in the spray, has a pronounced keratolytic (softens and promotes the rejection of the stratum corneum affected by fungal pathogens) and moisturizing effects. This component of the drug is able to increase the level of penetration of the drug into the skin and create increased concentrations of terbinafine in the skin. Urea has the ability to quickly restore the epidermis.
Butylhydroxytoluene, which is part of the Fungoterbin spray, is an antioxidant that actively stimulates regeneration processes. With external use, it inhibits free radical processes.
Terbinafine is not able to affect the metabolism of hormones or other pharmacological preparations.
With external use, the absorption of this medication is 5%. It has a minor systemic effect.
Indications for the prescription of the drug
Spray "Fungoterbin" is prescribed to patients during therapy and prevention of the following pathological phenomena:
- fungal infection of the skin: mycosis of the feet, inguinal epidermophytosis, fungal infection of smooth skin caused by dermatophytes;
- skin infections caused by Candida yeast-like fungi;
- multicolored lichen provoked by Pityrosporum orbiculare;
- seborrheic dermatitis on the scalp.
Doctor's prescriptions must be strictly followed.
Rules of use and dosage
As indicated by the instructions for use with the Fungoterbin spray, it is recommended that adult patients, as well as children after 12 years of age, apply the drug to the affected skin 1-2 times a day. Before using the medication, it is necessary to clean and dry the affected areas well. The spray must be sprayed in an amount sufficient to moisten the treated surface, and, in addition, apply to adjacent areas of intact skin.
With dermatomycosis of the legs, trunk, and feet, the spray should be used within 1 week once a day; with candidiasis of the skin - within 2 weeks 1 or 2 times a day; with lichen - 1 or 2 times a day for 1 week.
The experience of treatment with this drug in children is quite limited, and therefore the use of the antifungal agent under the age of 12 years is prohibited.
What else does the application instruction for Fungoterbin tell us?
Side effects of use
During the use of the drug spray, some negative side reactions may occur, including:
- Local. Rarely - itching, redness or burning sensation at the site of application of the medication. Discontinuation of antifungal therapy is required only in case of their increased intensity and severity.
- Allergic manifestations. Rarely, generalized redness or rash, urticaria, repeated allergic reactions, angioedema.
Contraindications
The medicinal spray "Fungoterbin" is contraindicated in the following cases:
- age less than 12 years;
- high sensitivity to the main element of the drug or its other substance.
With some caution, this medication should be used for liver or kidney failure, inhibition of blood formation in bone marrow structures, alcoholism, tumors, metabolic pathologies, and occlusive ailments of the limb vessels.
Before using the drug "Fungoterbin" it is recommended to get a doctor's consultation.
Use during pregnancy, lactation
Since the clinical experience of prescribing the drug during pregnancy in women is very limited, it is possible to use the antifungal medication “Fungoterbin” in the form of a spray solely for strict medical reasons, when the expected beneficial effect for the mother will be higher than the risk to the fetus.
The main substance of the drug, terbinafine, can be excreted in breast milk. However, when using a medication in the form of a spray, only a small amount of the active element is absorbed through the skin of a nursing mother, therefore, a negative effect on the baby’s health is unlikely.
In the process of conducting experimental tests of teratogenic properties in the main component of the drug was not detected. Until now, no defects of development and growth due to the use of the drug Fungoterbin have been reported.
Special recommendations
A decrease in the severity of the clinical symptoms of a fungal infection is usually observed in the early days of therapy with this medication. With irregular use or premature discontinuation of therapy, there is a chance of a resumption of infection. If after 14 days there are no signs of improvement in the patient, the clinical diagnosis should be verified.
The medication spray is intended for external use only. It is recommended to avoid contact with the drug in the eyes and mucous membranes. In case of accidental contact with eyes, rinse immediately with water. In case of persistent pathological phenomena and irritation, it is advisable to consult a specialist.
The use of "Fungoterbine" should be careful.
Overdose Signs
No cases of the development of an overdose with the Fungoterbin medical device were reported. With accidental oral administration, side effects such as nausea, changes in appetite, abdominal pain, diarrhea can be expected. In addition, the presence of ethanol in the medicine must be considered.
Analogs of spray "Fungoterbin"
This pharmacological agent has a wide selection of analogues. These include the following medicines:
- Atifin;
- "Binafin";
- "Bramisil";
- Lamisil
- Lamicon;
- Lamifungin;
- "Lamellar";
- Mikonorm;
- "Mikoterbin";
- "Tebikur";
- "Terbizil";
- Terbyx;
- Terbinox;
- "Thermicon";
- "Terbifin";
- "Exifin."
The doctor should select substitutes.
Reviews
Probably, every person suffered from fungal diseases at least once in his life. At the same time, patients use a huge variety of various medications, one of which is Fungoterbin in the form of a spray. This drug is currently quite popular and in great demand. Patients in the reviews of "Fungoterbine" explain this by the fact that the medication is very convenient to use and copes well with fungal skin lesions. The spray is easily sprayed and applied evenly on the surface of the lesions, does not pinch the skin, does not cause pain and discomfort. It is quickly absorbed and does not stain clothes.
Doctors also put aside reviews about the Fungoterbin spray, which indicate that this medicine is often prescribed for mycoses and foot fungus today. Experts are confident in its effectiveness and safety.
If we talk about adverse reactions from the use of this antifungal agent, then they occurred only in very rare cases. Basically, patients did not notice such phenomena, or they had a short-term nature and low severity. Among these phenomena, slight reddening of the skin was most often observed.
The article examined the instructions for the spray "Fungoterbin."