The drug "Ksefokam" refers the instruction to non - steroidal anti - inflammatory drugs with the active substance - Lornoxicam (Lornoxicam). This product is available in two forms: tablets for oral administration and powder for injection in the form of a solution. The proposed instruction is for the Xefocam drug in the form of a powder for injection.
The release form and composition of the drug "Xefocam"
The instruction describes the preparation in the form of a dry powder for the preparation of injection solutions of 10 cm³ in bottles, which are packaged in packages of 1, 5 and 10 pcs. The kit also comes with a solvent (sterile water - ampoules of 2 cm³) and without it. One vial contains 8 mg of lornoxicam.
Pharmaceutical action of the drug "Xefocam"
The instruction informs about the expressed analgesic and anti-inflammatory effect of the drug.
Indications
It is used in the presence of moderate and severe pain in the following cases:
- arthralgia, myalgia, neuralgia, pain in the spine, sciatica, lumbago, migraine, toothache and headache, algodismenorea;
- pain with burns, injuries, oncological diseases.
For symptomatic treatment of pain and inflammation in degenerative and inflammatory rheumatic diseases:
- rheumatoid arthritis, osteoarthrosis, ankylosing spondylitis;
- articular syndrome, in case of exacerbation of gout;
- bursitis, tenosynovitis.
Contraindications to the use of Xefocam powder
Instruction manual forbids drug for:
- Hypersensitivity to lornoxicam or other ingredients;
- the presence of hypersensitivity to acetylsalicylic acid or substances from the NSAID group (ibuprofen, indomethacin) in the anamnesis;
- hemorrhagic diathesis or blood clotting disorders;
- gastrointestinal ulcer in the acute phase;
- ulcerative colitis;
- Severe violations of the liver;
- moderate or severe renal impairment;
- hypovolemia or dehydration;
- confirmed or suspected hemorrhagic stroke;
- bronchial asthma;
- heart failure;
- decrease in hearing acuity;
- during pregnancy and lactation;
- under the age of 18 years.
Ksefokam: instruction
Injections are given IM or IV for pain in the postoperative period, with an attack of acute lumbago, ischalgia. The initial dose is 8–16 mg. The maintenance dose of the drug - 8 mg - two injections per day. The dose should not be higher than 16 mg / day.
Rules for the preparation of the medicine "Xefocam"
Injections are prepared as follows: 8 mg of powder is dissolved in 2 cm³ of water for injection. The solution is administered in / in or in / m. The finished solution must be entered within 24 hours. I / O should be administered for at least 15 s, and / m for at least 5 s.
Possible side effects
In the digestive tract and liver in the form of:
- abdominal pain, diarrhea, dyspepsia, nausea, vomiting;
- rarely - flatulence, dry mouth, gastritis, esophagitis;
- the formation of peptic ulcers and / or bleeding in the digestive tract, stomatitis, glossitis, colitis, dysphagia,
- hepatitis, pancreatitis, impaired liver function.
Possible manifestations of allergic reactions in the form of:
- skin rash;
- hypersensitivity reactions, accompanied by tachycardia, shortness of breath, bronchospasm, Stevens-Johnson syndrome, exfoliative dermatitis, angiitis, fever, allergic rhinitis, lymphadenopathy.
In the central nervous system, it is rare in the form of headaches, dizziness, drowsiness, a state of excitement, sleep disturbances, tinnitus, hearing loss, dysarthria, hallucinations, migraines, peripheral neuropathy, syncope, and aseptic meningitis.
special instructions
Caution must be exercised in the use of anemia and hypertension.
Interactions
With the simultaneous administration of platelet aggregation with anticoagulating or inhibitory substances, the risk of bleeding increases. FROM derivatives of sulfanylureas can enhance the hypoglycemic effect of the latter. With other NSAIDs or GCS - increase the risk of developing negative manifestations in the digestive tract, and with diuretics - reduce the diuretic and hypotensive effect. When used β-adrenergic blockers and ACE inhibitors, the drug reduces their hypotensive effect.
Overdose
Perhaps increased manifestations of side effects of the drug "Xefocam". Overdose treatment is symptomatic.