"Mexidol" refers to the group of antioxidants, the drug has antihypoxic, as well as nootropic and anticonvulsant effects, protects myocardial cells.
The medication is produced in two dosage forms: tablets and injections. The first type of drug is suitable for oral use. Milk-colored tablets with a beige hue, they are packaged in blisters of ten pieces.
The composition of the medication includes one active component - ethylmethylhydroxypyridine succinate, as well as additional components. What reviews and instructions for use do Mexidol tablets have?
Act
The drug is considered an inhibitor of free radical processes, as well as a membrane protector. "Mexidol" has a nootropic, as well as anti-stress and anti-hypoxic effect on the body.
Under the influence of the drug, the body's resistance to various negative factors of the surrounding and internal environment increases: shock, stress, as well as poisoning with alcohol and drugs, impaired blood microcirculation, ischemia.
The medication increases the concentration of dopamine in the brain, improves metabolism in its tissues, helps normalize microcirculation and provide cells with oxygen. Under the influence of the drug, cholesterol in the blood decreases.
The active component of Mexidol helps to effectively remove toxins from the body, which accumulate during alcohol poisoning, which subsequently improves the functioning of the internal organs and central nervous system.
Under the influence of the medication, the pharmacological effect of tranquilizers, as well as antidepressants, sleeping pills and anticonvulsants, is enhanced, which allows to reduce their daily concentration, as well as reduce the risk of adverse reactions.
According to the instructions for use and reviews for Mexidol, tablets improve the condition of the myocardium with ischemia, restore the contractility of the heart muscles and stabilize the blood microcirculation in the ventricles.
What is the drug for?
Tablets are prescribed to people for preventive purposes to prevent, as well as eliminate the following conditions:
- Ischemic stroke (cerebrovascular accident with damage to brain tissue, impaired function due to difficulty or stop the flow of blood to a particular department).
- Transient ischemic attacks (acute transient disturbance of blood microcirculation in the brain according to the ischemic type).
- Traumatic brain injury.
- Vegetative-vascular dystonia with frequent bouts of panic attacks (a complex of functional disorders, which is based on impaired regulation of the vascular tone of the autonomic nervous system).
- Impaired functioning of the brain.
When is the medicine still used?
According to the instructions and reviews for Mexidol, tablets are recommended for use in the following situations:
- Disorders of the brain and capillaries, which are caused by the deposition of atherosclerotic plaques.
- Coronary heart disease (organic and functional damage to the muscles of the heart, which is provoked by a deficiency or cessation of blood supply to the heart muscle).
- Neurosis (the collective name for a group of functional psychogenic reversible disorders that tend to be protracted).
- Psycho-emotional disorders.
- Withdrawal syndrome (a group of symptoms of various combinations and severity that occur when the substance is completely discontinued).
- Diseases of the heart and blood vessels.
- Chronic stress
- Sclerosis (a chronic autoimmune disease in which the myelin sheath of the nerve fibers of the brain and spinal cord is affected).
Contraindications
Tablets have certain restrictions on the use, so before starting treatment it is necessary to familiarize yourself with the instructions. Prohibitions include the following conditions:
- Severe liver disease.
- Individual intolerance to the components.
With an "interesting situation", breastfeeding and people under the age of twelve, this medicine is not administered or is prescribed with extreme caution.
Dosing Mexidol
According to the instructions for use and reviews on "Mexidol" in tablets, for adults, the drug is intended for oral use. Therapy begins with one piece three times a day, if necessary, increasing a single dosage to two tablets per day. The duration of treatment depends on the diagnosis, but should be at least two weeks.
Daily dosing varies from 375 to 750 milligrams, the frequency of use is 3 times. The maximum permissible concentration of the active substance is 800 mg per day, which corresponds to six tablets.
Patients with cardiac ischemia for elimination and for prophylactic purposes to prevent symptoms of the disease is recommended to use Mexidol for at least six weeks. During likely exacerbations, therapy should be repeated.
If the drug is prescribed to neutralize the symptoms of alcohol withdrawal, the duration of therapy varies from five to seven days.
How to use the drug during pregnancy
Since there is no reliable information regarding the effect of Mexidol on the intrauterine development of the fetus, women are not treated with this medication in a position.
In addition, it is also not known whether the drug with breast milk is excreted and how this can affect the baby's body. Therefore, therapy among nursing mothers is not carried out. According to patient reviews, Mexidol tablets can be taken during lactation only after the termination of breastfeeding.
Adverse reactions
During the use of Mexidol, a person may manifest some negative effects:
- Pain in the stomach.
- Heartburn.
- Vomiting.
- Diarrhea.
- Intestinal patency.
- Flatulence (excessive accumulation of gas in the intestine, which is manifested by bloating, possibly abundant secretion of a large amount of digestive gas).
- Spastic pain (pain as a result of contraction of the muscles of the legs, arms, intestines, stomach, blood vessels).
- Allergic rashes on the skin.
- Urticaria (a defeat of the epidermis of an allergic origin, which is characterized by the rapid onset of itchy blisters).
According to reviews of Mexidol tablets (125 mg), negative effects disappear after drug withdrawal, but if lethargy increases and there is no reaction to irritants, then the patient must urgently visit a medical specialist.
Does Mexidol interact with other medicines?
The drug, while taking it with ethyl alcohol, reduces the toxic effect of the latter. With the combination of Mexidol with nootropics, antipsychotics, as well as antidepressants, anticonvulsants, their pharmacological effect increases, so patients need a dosage adjustment.
Is the drug compatible with alcohol?
Mexidol is a medicine that has a strong antioxidant effect. For this reason, it is often used in various fields of medicine.
The drug effectively restores the work of the neurological and psychological sphere. In addition, the medication helps to regenerate liver cells.
"Mexidol" has a hepatoprotective and nootropic effect, its purpose is considered one of the most effective and popular methods of treatment of alcohol withdrawal syndrome, which occurs during intoxication of the body with ethanol.
Mexidol and spirits are believed to be compatible. Some people tend to believe that a medication to some extent suppresses the effect of the latter. But, unfortunately, this opinion will be wrong, since the active substance of the drug, getting into the tissues of the brain and liver, only eliminates the existing signs of intoxication and eliminates the disease.
It must be remembered that the drug does not prevent the appearance of negative symptoms of a hangover, but only neutralizes its consequences:
- Reduces headache intensity.
- Reduces the severity of signs of intoxication.
- Improves the process of discharge from the liver of residues of toxic components of alcohol.
But Mexidol is not able to protect the liver from cirrhosis or irreversible mental disorders if the patient continues to take alcohol in high concentrations.
Expert Advice
According to the instructions, Mexidol goes well with any medications that are designed to eliminate somatic pathological processes.
For patients under the age of twelve, this drug is not allowed to be used, since it has not been fully studied how the medicine can affect the child's body.
During therapy with this medication, people need to avoid driving vehicles and controlling mechanisms that require increased attention.
Analogs
According to reviews of Mexidol tablets, it is known that the drug has a number of substitutes. These include:
- "Cerecard".
- "Medomeksi".
- Neurox.
- Mexiprim.
- Mexifin.
- Mexipridol.
- Mexidant.
Before changing the prescribed medication with one of the above substitutes, you must always check with your doctor for daily dosing, as well as age restrictions.
How to store the medicine
Mexidol can be purchased with a doctor’s prescription. Shelf life is thirty-six months. When storing the drug, direct radiation should be avoided, kept away from small children. The cost of the drug varies from 250 to 2200 rubles.
Patient Reviews
People who took Mexidol in tablets characterize it as an effective medicine that can reduce the severity of signs of acute and chronic disorders of blood microcirculation in the brain.
The drug also helps in withdrawal symptoms: almost all people note a decrease in cravings for addictions. In addition, their overall quality of life is significantly improved.
Which is better, Mexidol tablets or injections? According to reviews, it is known that in tablet form and injections, the medication helps to eliminate unpleasant symptoms, which are noted with vegetovascular dystonia - a disease from which almost a third of the world's population suffers to one degree or another.
Despite the fact that little patients are not prescribed Mexidol, many doctors note that injections help to quickly normalize the condition of the child after a cranial injury, and neutralize the unpleasant symptoms provoked by oxygen starvation.
In addition, the drug is effective for children who are born with symptoms of hypoxia. Improving the condition of babies and normalizing the nutrition of their brain is observed already an hour or two after using the drug.
The development of vegetative-vascular dystonia, as well as the occurrence of most other pathological processes, is to some extent associated with free-radical oxidation. "Mexidol" is an antioxidant that effectively suppresses these pathogenic processes.
The medication stabilizes the biological membranes of cells, activates the energy-synthesizing functions of a two-membrane organoid of a eukaryotic cell, regulates the functioning of nerve endings, and modulates the processes of passage of ion currents. In addition, Mexidol helps to enhance the binding of endogenous substances, as well as improve synaptic transmission and the relationship between brain structures.
But along with the positive feedback about Mexidol, you can also find the opinions of patients who were dissatisfied with the medicine. Negative reviews about injections, as a rule, are associated with the fact that the medication in some situations provoked adverse reactions in the form of nausea and headaches.