Every third inhabitant of the planet suffers from hypertension to one degree or another. It is considered the most common and common disease of the vascular system. In addition, doctors attribute it to extremely dangerous, because it very often leads to heart attacks, strokes and deaths. It is not surprising that pharmaceutical companies are constantly working on the development of new and effective drugs designed to make life easier for people with high blood pressure. According to the latest medical data, it can be judged that drugs based on one active substance do not always successfully cope with the problem. Therefore, doctors have to supplement them with other drugs or significantly increase the dosage, which negatively affects the well-being of patients.
Today, therapists are trying to prescribe combination drugs in which two substances simultaneously affect the patient's body, perfectly complementing each other. Pressure pills "Equator", reviews of which we will use in the article, showed themselves only on the good side. Today they are leaders in the fight against hypertension. Below we will discuss the instructions for Equator pressure pills, reviews and analogues of this drug. In addition, readers will receive information about its side effects, indications for use and features of the reception.
general characteristics
When it comes to combination medicines, such as Equator pressure pills (we will discuss instructions and reviews a little later), it must be borne in mind that most often they become the basis of calcium channel inhibitors and blockers. These substances are perfectly combined and even enhance the effect of each other. In this regard, the tool effectively performs its basic functions and gives a minimal amount of side effects. The latter factor allows you to expand the group of people to whom tablets can and should be used.
Referring to the instructions for the Equator pressure pills, patients write in their reviews that even the first dose of the medicine lowered the pressure to normal and returned the joy of life. Approximately one hour after the tablet enters the patient's body, a decrease in pressure occurs, and after six hours, the maximum concentration of active substances in the blood is observed. The duration of action of the drug (reviews of tablets from the Equator pressure, this fact is fully confirmed) is calculated in days. Such a schedule for taking medication is very convenient for middle-aged people who spend a lot of time at work. By the way, they are the majority among patients with hypertension.
Release form
The manufacturer produces the drug only in tablet form. In reviews of the Equator (it helps very well by pressure), patients indicate that each tablet is round in shape and white. A slight deviation from the main color towards a light beige shade is allowed. The tablets are flat and on one side the manufacturer has put at risk. The second side has an engraving, which is the initial letters of the names of the active substances.
The package usually indicates the dosage of both components, which are the basis of tablets from high blood pressure. In the reviews about the "Equator" it is noted that in each cardboard bundle there are from one to six blisters. Each contains ten capsules.
In Russia, only Gedeon Richter supplies the drug. This Hungarian company is well known to our compatriots, as are the medicines it produces. It is known that the manufacturer specializes in cardiac and hormonal drugs. It also supplies high quality antibacterial and anti-inflammatory drugs.
Active ingredients and dosage
Equator pressure pills in reviews are often positioned literally as a panacea. After all, the combined drug very quickly removes the unpleasant and dangerous symptoms of hypertension. And all this thanks to its active substances - amlodipine and lisinopril.
To date, in pharmacies you can find a drug with a different dosage of these components (it is indicated in milligrams):
- Pills for pressure "Equator" 5 and 10 (the reviews indicate that they are prescribed for people with hypertension at the initial stage).
- Tablets 10 and 20.
- Equator 5 and 20.
The first figure shows the concentration in the drug of amlodipine, and the second - lisinopril. Depending on the dosage, the concentration of excipients also changes, but their list always remains the same. In the reviews about the use of tablets from the Equator pressure, the composition is described as follows:
- Active substances.
- Excipients: two types of cellulose, magnesium stearate, sodium carboxymethyl starch.
All of these components are safe for humans, since the drug has undergone a number of clinical trials before being sent to production. It is worth noting that Gideon Richter pays special attention to this issue and carefully monitors the safety of its medicines.
Each of the active substances has a number of characteristics that patients rarely cite in their reviews about the Equator pressure pills and the composition of the drug. Therefore, we will devote our attention to this issue by talking about the basic substances themselves and the mechanism of their effect on the body.
Amlodipine: characteristics and a brief description
This substance belongs to third-generation blockers and is responsible for protecting cells from the ingress of excess calcium. First of all, amlodipine blocks calcium in the cells of the vascular system and myocardium. It also helps to reduce smooth muscle tone. This is what plays an important role in normalizing the patient’s condition, which occurs as soon as possible after taking one pill from Equator pressure. In reviews, his lightning help is noted by almost all patients.
Pharmacists indicate several properties of the substance described by us. First of all, it is, of course, a decrease in blood pressure. Moreover, this effect lasts a long time. This period directly depends on the dosage of the drug prescribed by the doctor. In parallel, the base substance "Equator" has antisclerotic properties and helps to reduce left ventricular hypertrophy.
The prolonged exposure to amlodipine is provided by several factors:
- slow absorption in the gastrointestinal tract;
- extensive distribution throughout the body;
- long elimination period.
The active substance promotes the flow of oxygen to the heart muscle. Thanks to this, the patient gets the opportunity to better tolerate physical activity than before, and attacks of heart failure are minimized. In reviews of the Equator pressure pills, patients often write that the drug significantly reduced blood viscosity. Thus, the risks of blood clots are neutralized, which often affects people with hypertension.
Lisinopril: mechanism of action on the body
In patients' reviews of Equator pressure pills, information can be found that the drug does not affect the rate of heart muscle contractions. This effect is provided precisely by the second active ingredient of the drug - lisinopril.
It also improves blood circulation and even reduces pressure in the capillaries of the lungs. Once in the body, lisinopril increases the content of vasodilating substances synthesized by the body in the circulatory system. A similar effect helps patients to tolerate physical activity well and not experience unpleasant sensations.
If we talk about the complex effects of both substances, it is impossible not to note that they enhance the effect of each other. An important effect noted in the reviews about the use of tablets from the Equator pressure is a decrease in the risk of edema. Amlodipine promotes fluid retention in the body, however, lisinopril acts as a inhibitory factor and normalizes water metabolism, thereby removing swelling.
Due to the described effect of the Equator pressure pills (we will provide patient reviews in one of the sections of the article), even people with diabetes can be taken for a long time. They may not be afraid of the development of hypoglycemia, which is often facilitated by the use of drugs for hypertension.
Indications for use and pharmacokinetics
Interestingly, in customer reviews of Equator pressure pills, a list of indications is almost never given. Doctors say that this is understandable, since the drug is prescribed only if one single diagnosis is identified - arterial hypertension. Unfortunately, the danger of this disease, many of our compatriots underestimate. Although in the West, patients are more serious about such a diagnosis and never let treatment go by its own. Otherwise, the likelihood of developing concomitant diseases is high. Their list is extremely wide: heart failure, vision problems, heart attack and stroke, kidney disease, thrombosis and aortic diseases.
Detailed instructions for the Equator pressure pills and reviews about them give complete information that they are most often prescribed to people who have already been treated for hypertension and have not received a noticeable improvement in their condition. It is also noted that the drug described by us can be used at any stage of the disease and even during its exacerbation.
The doctor in charge of detecting arterial hypertension in patients with diabetes mellitus or kidney problems is likely to prescribe Equator tablets from pressure (the drug reviews confirm this fact).
When it comes to pharmacokinetics, you need to understand that it is considered separately for each of the active substances. For example, amlodipine is absorbed by almost ninety percent. Its maximum content in the blood is reached in about ten hours. After a week of taking, the concentration of amlodipine in the blood becomes stable and practically does not change. The metabolic process occurs in the liver, and seventy percent of the body is eliminated through the kidneys. The remaining percent is excreted along with bile. It is noteworthy that the body is completely cleared of amlodipine in about two days. In patients with liver and kidney diseases, as well as the elderly, this period increases.
Lisinopril, in turn, is absorbed by only thirty percent. In this case, metabolism in the body is not carried out, and the substance is excreted through the kidneys in about twelve hours. It is worth considering that in the reviews about the Equator pressure pills, the drug is described as a remedy that can harm pregnant women and those who breastfeed the baby. It is proved that the drug easily penetrates the placental barrier and is found in high concentration in breast milk.
Contraindications
In the instructions for use for tablets from pressure "Equator" and reviews about them a lot of attention is paid to the list of contraindications. It is worth noting immediately that it is quite extensive and includes both explicit contraindications and relative ones.
The first category includes sensitivity to the components of the drug. If this point is neglected , the patient risks an allergic reaction. Also, tablets should not be taken after cardiogenic shock and in cases of Quincke edema. Equator is contraindicated for persons under the age of eighteen; for them, doctors will choose another effective remedy with a less powerful effect. Women in position should also refuse treatment with this drug, since it has a negative effect on the development of the fetus. During lactation, "Equator" should not be used, as the baby will receive a significant dose of the drug along with breast milk.
The list of relative contraindications requires special treatment. If a patient identifies diseases that we list a little later, the doctor should carefully monitor the patient's condition through weekly examinations. This category of patients includes people with diabetes, kidney and liver diseases, as well as those who follow a low sodium diet. Elderly people and patients with coronary insufficiency need special monitoring of their health when taking "Equator". With some caution, you need to drink tablets for people who have had myocardial infarction a month before the drug is prescribed. This also includes tachycardia, bradycardia and problems with cerebral circulation.
Instructions for use
You need to take "Equator" strictly according to the instructions, since this drug belongs to the category of very strong. A patient is shown only one tablet per day. It amounts to both the minimum and maximum dosage at the same time, which in no case should be exceeded. It is recommended to drink the tablet in the morning without chewing, and drink with a large glass of water.
The attending physician, depending on the degree of arterial hypertension in the patient and the severity of concomitant diseases, prescribes a certain dosage, indicated on the package of the drug.
Even persons who do not have concomitant diseases, it is necessary in the first month of treatment to monitor the condition of the liver and kidneys, as well as monitor the content of sodium and potassium in the blood. If the tests during the treatment have become worse than before him, then the doctor will cancel the previously prescribed dosage and replace it with a smaller one. In the case when this does not give a result, the drug will be replaced with analogues (in the reviews about the Equator pressure pills they are sometimes mentioned).
It must be borne in mind that a few days before the start of treatment, patients should refuse to take diuretic drugs. If, for certain reasons, they are necessary for the patient, then the initial dosage will be half of one tablet. The same dosage is indicated for persons with liver disease.
Many doctors cautiously prescribe "Equator" to patients with low body weight. It is noted that they may develop liver and kidney diseases during treatment. Therefore, most often the dosage for them is reduced.
Side effects
Doctors warn their patients that any adverse reactions of the body to the Equator tablets pass quite quickly. Therefore, doctors rarely prescribe the drug. Unpleasant symptoms during treatment occur in only eight percent of patients. However, we list all the possible reactions that are noted in the manufacturer's instructions.
"Equator" can cause an allergic reaction, manifested by swelling of the mucous membranes. The cardiovascular system in some cases responds to medication with tachycardia and arrhythmia. It is extremely rare, but there are still cases of dry mouth, abdominal pain, decreased appetite and jaundice.
In a certain group of patients, tablets cause skin rashes, such as urticaria, for example. At the same time, itchy skin can occur, which will be quite difficult to relieve.
Despite the fact that side effects from the Equator are extremely rare, tablets can significantly affect the genitourinary system. Patients of both sexes in these cases complain of frequent urination, the development of kidney diseases of a different nature and severity, as well as other problems.
Great troubles for the patient can provoke a reaction of the nervous system to taking the drug. It is usually expressed in constant drowsiness, which reduces performance and affects concentration. In some cases, patients felt confusion and a loss of orientation in space. Often, such symptoms are accompanied by sudden changes in mood, which intensify and aggravate against the background of hormonal disorders already existing in the patient.
"Equator" and its analogues
In reviews, the pressure pills described by us sometimes have to be replaced with similar remedies. Moreover, they are conditionally divided into two groups: drugs with an identical composition and drugs, where amlodipine is combined with other substances. Both those and other products are sold in pharmacies by prescription and are quite common.
The first group of drugs includes Eklamiz, produced in Russia. Depending on the dosage, its price ranges from four hundred to six hundred rubles. Also good reviews are received by the Indian "Equacard" and "Tenlisa" produced in Slovenia.
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