An infection such as a fungus on the nails is a very urgent problem. It brings discomfort to life for several months, because in addition to painful sensations, a person experiences a psychological complex, nervously hiding nails affected by the fungus from prying eyes. Moreover, this infection can affect the nail plate on both the toes and on the fingers.
To get rid of this problem, you have to try a lot of remedies. And the whole secret of getting rid of nail fungus is that the treating medication must have the property of deep penetration into the tissues in order to destroy all fungal spores that coexist both in and under the nail plate itself, leading to its complete destruction.
The range of remedies offered by pharmacies is very large. If we are talking about the initial stages of infection with fungal spores of nails, then drugs that are applicable externally - ointments and creams - are more often used. They can significantly help the body fight infection with persistent human immunity.
If we are talking about the later stages, then external drugs do not lead to a positive outcome of recovery. In the later stages, when the fungus progresses through the body, because it can affect not only the nail plates, but also the internal organs, you should still prefer drugs that act on the infection from the inside, therefore, those that are taken orally - tablets or capsules, syrups or suspensions, as well as solutions for injection.
Nail fungus than to treat?
The development of a fungal infection on the nails is indicated by such signs as a thickening of the nail plate, its darkening, brittle nails, staining, unpleasant odor, pain.
Before undertaking the treatment of fungus on the nails, you should visit a doctor who, after examining the nails, will take a few particles of the nail plate for examination and determine what infection develops, and only after that you can start an effective fight using effective drugs that the doctor will prescribe.
Those who have firsthand experience of fungal infections know that this problem is not so simple. A lot of people leave positive feedback about Fluconazole. From nail fungus is the most common remedy that is in every pharmacy. Moreover, it is not too expensive. Treatment with it can last more than six months, but as many have noted, the effect is worth it to undergo a full course of therapy and forget about the fungus forever.
What is the drug "Fluconazole", as well as its basic properties, the mechanism of action on fungal infections, similar drugs is described below.
Means "Fluconazole": pharmacological properties
This medication belongs to the group of antimicrobial, antifungal drugs with a wide spectrum of action. The medicine "Fluconazole" is rapidly absorbed in the digestive tract, the maximum concentration of the active substance is achieved half an hour after oral or intravenous administration. This drug penetrates into all tissues of the body, is not metabolized and is excreted from it unchanged by the kidneys. The withdrawal period is more than 30 hours.
Describing the action of the drug "Fluconazole", it is necessary, first of all, to note the fact that this agent is an inhibitor of the synthesis of sterols in fungal cells, which leads to damage to the cell membranes thereof, therefore, to their complete destruction.
This therapeutic antifungal agent effectively affects the following types of fungi: Blastomyces dermatitides, Candida spp., Trichophyton spp., Cryptococcus neoformans, Coccidiodes immitis, Histoplasma capsulatum, Microsporum spp.
The drug does not affect the fungal pathogens of the genus Aspergillus. Of all the antifungal medicines available in the pharmaceutical market segment, Fluconazole is noted to be the most effective because it covers a large list of them in the fight against fungal infections.
Release form
The drug "Fluconazole" is available in several forms. So, you can buy a ready-made syrup or powder in a pharmacy for reconstitution of a suspension for oral administration, tablets or capsules, injection, gel (cream, ointment), candles.
It is worth paying attention that the instructions that are distinctive for each form of the drug "Fluconazole" are attached. The price of the medicine in capsules is 40 rubles, in tablets - 50 rubles, in powder - 150 rubles, in syrup - 200 rubles, in solution for injection - 300 rubles, in the form of a gel - 250 rubles, in candles - 150 rubles.
It is worth remembering that for the treatment of nail fungus, all forms of the drug are applicable. At the initial stages of the manifestation of fungal infections on the nails, you can use "Fluconazole" ointment. But for the treatment of progressive fungi, any of the forms taken orally is suitable.
Many about the drug "Fluconazole" reviews from nail fungus are advised to take either capsules or tablets. They are the cheapest of the entire list and easy to receive.
In many cases, the “Fluconazole” preparation is still important, the instruction, the price for poor health always goes by the wayside.
The pharmacokinetics of all forms of the drug is similar, so you can easily switch from one to another, waiting for an effective result. But in no case should you use two or more forms at the same time so that there is no overdose.
Many, of course, with so many forms of the drug, the question arises: "How to take" Fluconazole "and in what dose?" We will talk about this below.
Instructions for use
The drug "Fluconazole" is recommended for inhibition of fungal pathogens with the following diagnoses:
- cryptococcosis;
- all types of candidiasis;
- mycoses of the feet, body, and skin of the groin;
- color lichen;
- epidermal mycosis;
- meningitis;
- sporotrichosis;
- radiation therapy;
- chemotherapy;
- prevention of the development of fungal infections after surgery;
- onychomycosis.
The latter is the very problem called nail fungus.
If you evaluate the instructions on the drug "Fluconazole" reviews, it helps to get rid of nail fungus for both adults and children.
Comparing this remedy with other drugs of the antifungal group, one cannot yet call its effect completely harmless to the human body. Many people are faced not only with the positive effect achieved with this drug, but also with side effects, which will be described a bit below.
Although Fluconazole is sold in any form without a doctor’s prescription, the instruction recommends taking it only as prescribed by the doctor, who determines the required dose after the examination procedure and the tests submitted by the patient.
Contraindications
Before telling how to take "Fluconazole", we dwell on contraindications to its reception, as indicated by the instruction. Her recommendations state that the drug should not be prescribed to children under the age of four.
It is imperative to determine the compatibility of Fluconazole with other drugs so as not to harm the body weakened by various fungal infections.
Since "Fluconazole" has the property of penetration into all tissues of the human body, the instruction for the drug does not recommend it to be prescribed to pregnant and breast-feeding women.
Hypersensitivity is a direct indication that the drug is not suitable for treatment.
Diagnoses such as liver and kidney failure are also an obstacle to taking Fluconazole.
Dosage and administration
In taking the drug "Fluconazole" dosage has a certain value. It is prescribed by the doctor, if the medicine is taken independently, then you need to carefully read the instructions. Each form of the drug is prescribed individually.
"Fluconazole" (cream) is applied to the affected areas with a thin layer of fungus. If the nail plate is affected, then the product must be applied not only to its surface, but also to the skin of the finger around the circumference of the nail, rubbing it with slow movements. "Fluconazole" (ointment) is applied once a day. This should be done before bedtime, when the hands do not come into contact with water, household items, legs do not soar in shoes.
It does not matter how to take Fluconazole inside the drug - before or after meals. The medicine is rapidly absorbed in the digestive tract, as mentioned above. Fluconazole capsules and tablets (150 mg) are taken from the fungus on the nails one at a time once a week. But the syrup and suspension are prescribed by the doctor, depending on the type of progressive fungus and the age of the patient.
Treatment of nail fungus with capsules or tablets can last more than six months, the result is the growth of a smooth, pink, healthy nail from the very bottom. Moreover, you need to take the drug until the infected nail is completely replaced by a healthy nail plate.
Many medical specialists still recommend using Fluconazole capsules from nail fungus. Their use does not cause any difficulties. This form is especially convenient for forgetful people or busy people. The drug "Fluconazole" (150 mg) in capsules is sold even one each in a pack.
It should be taken into account that in the treatment with "Fluconazole" it is not recommended to take alcohol in any form, as this can critically affect the kidneys and liver.
Feasible side effects
The high effectiveness of the drug in the fight against fungal infections, including those developing on the nails, and the correct dosage of the “Fluconazole” preparation do not mean that this medicine is safe for health. It is still recommended to take it as directed by a doctor.
A lot of people have already managed to test this remedy and leave positive feedback about Fluconazole. From nail fungus, of course, it is effective. But treatment is not always given without the discomfort caused by this medicine.
In particular, an antifungal drug can cause a decrease in appetite, tremors, changes in taste, dizziness and headaches, abdominal pain, nausea and vomiting, constipation, dry mouth, hepatitis, swelling of the body, skin rash and itching, weakness, and depression .
Compatibility with other medicines
It doesn’t matter if you take Fluconazole before or after meals, capsules or any other form of medication, you should be aware that it should not be taken simultaneously with the following list of medications, as this will adversely affect the functioning of the heart and circulatory system:
“Cisapride.”
“Terfenadine.”
- "Astemizole."
“Erythromycin.”
“Halofantrine.”
Means "Fluconazole" can affect the concentration in the human body (weaken or increase the effect) of the following drugs:
“Alfentanil.”
- Cyclophosphamide.
- Sirolimus.
“Voriconazole.”
- "Amitriptyline", "Nortriptyline."
- "Amphotericin B".
“Tacrolimus.”
“Fentanyl.”
“Celecoxib.”
- "Everolimus."
“Phenytoin.”
- Immunosuppressants Cyclosporin, Everolimus, Sirolimus, Tacrolimus.
- Anticoagulants.
- Short-acting benzodiazepines - Midazolam, Triazolam.
- Calcium channel blockers.
- Vinca alkaloids.
The drug "Fluconazole" does not affect the effectiveness of oral contraceptives.
Analogues of the drug
Very often people talk about fluconazole, but this substance is found in many drugs of domestic and foreign production.
Fluconazole was discovered by American medical luminaries, and it was released to the pharmaceutical market under the name Fluconazolum. Drugs that today contain fluconazole are considered to be its generics, that is, effective substitutes.
A medicine called Fluconazole is available in Russia and has earned the trust of millions of patients who have experienced it in personal medical practice.
Analogs can be selected for the "Fluconazole" preparation both by the identity of the active substance, and by the similarity of the effect on the destruction of fungal infections.
Synonyms of the medicine are such medicines as Diflunol, Flunol, Flukostat, Futsis, Diflazon, Mikoflukan, Mikomaks, Medoflukon, Fluzamed, Tsiskan, Fluconazole Geksal "," Flukorik "," Vero-Fluconazole ".
Drugs similar in action: Clotrimazole, Exoderil, Livarol.
Reviews of people who used the medicine in the treatment of nail fungus
Assessing the effectiveness of the drug "Fluconazole", analogues of this medicine, many people note positive trends in recovery. If we are talking about a fungus on the nails, then you do not have to expect an instant result in the treatment with this tool, however, this is one of the most effective medications, a full continuous course of therapy which is rewarded with healthy and strong new nail plates.
Since you want to get rid of the fungus on the nails instantly, many people buy at the high price of completely inactive drugs, while domestic manufacturers offer an inexpensive and effective remedy, as is often said by those who bothered to treat the infection.
Many parents who are struggling with the fungus of the nails of their children are satisfied with the action of this drug, because it is widely used in pediatrics.
Some reviews suggest that people take "Fluconazole" from several fungal lesions at the same time, eventually cure them forever.
Often people learn about the high effectiveness of this drug, having tested a lot of drugs, surprised that on pharmacy shelves you can buy a good tool almost for nothing. So, if the fungus on the nails is your headache - pay close attention to it.
As for the reviews of doctors, they also respond positively about this medicine. Thanks to this tool, people can get rid of serious ailments. Doctors prescribe Fluconazole in cases where other drugs are powerless in the fight against fungal infections.
Talking about the drug "Fluconazole", which is effective against a large list of fungal infections that take root in the human body, I would also like to note the fact that, without observing the rules of hygiene, it is difficult to cure the disease even with this remedy.
Therefore, follow these guidelines to help you get rid of the fungus forever:
- wear only your shoes, in public places (baths, saunas, fitness clubs, pools), take a removable pair of slippers;
- do not walk barefoot along the beach;
- you can’t keep your feet in excessive heat and excessive humidity, for the fungus these are the most favorable conditions for development;
- try to protect your nails from injury, because infections stick to damaged nails twice as often;
- do not put off the problem concerning the fungus on the nails in the farthest drawer of the table, it should be solved immediately, while the remaining nails on the arms and legs remain intact;
- if in the family someone is infected with a nail fungus, try to provide him with personal means and hygiene accessories;
- at the first signs of fungus on the nail plates, do not hide the defect under a thick layer of nail polish, which only preserves the infection and allows it to creep even more.
Following these basic recommendations, you can protect yourself from the troubles associated with onychomycosis, which is very, very difficult to treat. And if necessary, you need to start, of course, with a visit to a specialist who will not forget, of course, about such a drug in the appointment as "Fluconazole".
All analogues of this tool are the same in effectiveness, the difference is only in cost. Choose any of the list above, and proceed with the effective treatment of infection, which annoys significant discomfort, accompanied by destruction of nails and pain.
After reading this article, now you know how you can defeat forever fungal infections that have taken root on your fingernails and toenails. The drug "Fluconazole" contributes to a cardinal effect on spores of fungi, destroying them in the focus of infection and throughout the body.
The information in this article is for general reference only. If it is necessary to treat onychomycosis with the considered therapeutic agent, contact the doctor in charge directly for advice.
Such an approach to the urgent problem will make it possible to find out for sure which infection has settled on your nails and does not allow you to live in peace. Scraping from the nail plates will give a clear answer after laboratory tests, which infection to fight.
If the appearance of the fungus is obvious, the destruction of which is subject to the drug "Fluconazole", then its use will be appropriate. If some other type, then the doctor will prescribe other medications to undergo effective therapy.
Fungal infections most often develop in a weakened human body, so along with taking "Fluconazole" take care of strengthening your immunity.