"Bromhexine" - a drug that is used to treat acute, chronic diseases of the lungs, bronchi, accompanied by sputum difficult to separate. The main form of drug release is tablets.
The drug "Bromhexine" (tablets). Instructions: description, pharmacokinetics
The preparation contains the active substance bromhexine. Auxiliary components: lactose monohydrate, sugar, calcium stearate, starch.
The drug is well absorbed in the stomach, intestines, then undergoes a metabolic transformation in the liver. The drug is distributed throughout all body tissues. It is excreted by the kidneys in the form of inactivated compounds. The half-life of the components of the drug reaches two hours. The drug is able to penetrate into the brain tissue through the blood-brain barrier. A small part of it can pass through the placenta into the fetus. The excretion of the components of the drug may slow down with impaired renal function.
The drug "Bromhexine" (tablets). Instructions for use: pharmacodynamics
The drug has a pronounced expectorant and weak antitussive effect. Mucolytic effects are associated with the dilution and depolymerization of mucopolysaccharide, mucoprotein fibers. One of the most important features of the action of the drug is the stimulation of the synthesis of endogenous surfactant. It also increases the activity of the ciliated epithelium.
The drug "Bromhexine Berlin-Chemie" (tablets). Instruction: method of application, dosage
Ingestion is the only way to use this drug. It is used regardless of food intake. For adults, the dose is four tablets three times in one day. During therapy, it is recommended to consume a sufficient amount of water, which supports the secretolytic activity of the drug. The maximum treatment period is four weeks.
The drug "Bromhexine" (tablets). Instruction: side effects
Among the many side effects, dyspeptic disorders most often occur , increased transaminase activity of the liver, which is transient in nature, headache, sweating, cough, skin rash, bronchospasm.
The drug "Bromhexine" (tablets). Instructions: contraindications, drug interactions
The drug is forbidden to use in the presence of hypersensitivity to the components, peptic ulcer (stage of exacerbation), during periods of lactation, pregnancy. It is also contraindicated for use in children under six years of age.
It is allowed to prescribe this drug in combination with drugs of other groups that are used to treat bronchopulmonary diseases. It promotes the penetration of antibiotics into the lung tissue. The use in conjunction with codeine is unacceptable, this leads to difficulty in coughing up sputum. The drug is used in combination with herbal preparations, essential oils. Use in conjunction with alkaline solutions is also unacceptable.
The drug "Bromhexine" (tablets). Instructions: special instructions, overdose
For patients with impaired renal function, this drug is prescribed in slightly lower doses. With poor motility of the bronchi, a significant amount of sputum being separated, the use of the drug requires special care, this can cause a delay in the contents in the bronchi. Bronchial, asthma, gastric ulcer - diseases in which the drug should be used under the supervision of a doctor. The drug during lactation, pregnancy is used only in rare cases.
Symptoms of an overdose: vomiting, nausea, upset stomach and intestines. To date, no specific antidote for this drug has been developed. Therefore, all therapy in case of an overdose is reduced to gastric lavage, which should be carried out within the first two hours after taking the drug.