"Norkolut," the instruction indicates, is released in tablet form. The active ingredient of the drug is norethisterone (5 mg per 1tab), monophasic oral contraceptive. It belongs to the group of hormonal drugs of the gestagen series, which are obtained synthetically and have gestagen-like activity.
Norkolut ensures the transition of the inner layer of the uterus from the proliferation phase to the state of the secretory phase. Under its influence, the production of gonadotropin in the pituitary gland is blocked, thereby the maturation of follicles is inhibited, and the onset of ovulation is prevented.
"Norkolut", instructions for testimony
The drug is prescribed:
with premenstrual syndrome;
with anovulatory metrorrhagia;
with dysmenorrhea complicated by shortening of the secretory phase;
with uterine myoma;
with mastodynia;
with endometriosis;
with endometrial hyperplasia;
to conduct a test to determine the level of progesterone;
to stop and prevent lactation.
"Norkolut", dosage instructions
For the treatment of premenstrual syndrome, mastidinia, dysmenorrhea, the drug is prescribed in the period from the 16th day to the 25th day of the monthly menstrual cycle. A doctor assigns 1-2 tablets of 5 mg per day. Norethisterone is combined with estrogen.
With uterine myoma, the drug is prescribed in the interval from the 5th day to the 25th day of the monthly menstrual cycle. The doctor prescribes 1-2 tablets of 5 mg per day. The course is designed for up to 6 months.
To conduct a progesterone test, 10 mg of Norkolut tablets are prescribed for 10 days. Monthly, appearing on 3-7 days after taking the drug in the form of moderate discharge of a bloody hue, are considered physiologically normal. Allocations take 3-4 days.
With endometrial hyperplasia with the results of a histological analysis conducted less than 6 months before the start of the Norkolut treatment course, with anovulatory metrorrhagia per day, the doctor prescribes 1-2 tablets of 5 mg. The course is designed for a period of 6 days to 12 days. After a positive result is achieved, you should prescribe taking tablets in the interval between the 16th day and the 25th day of the monthly cycle, 1-2 tablets of 5 mg. Norethisterone is combined with estrogen.
In case of endometriosis "Norkolut", the instructions indicate that 5 mg norethisterone per day is prescribed during the period from the 5th to the 25th day of the monthly cycle. The course is designed for 6 months. The doctor may continue to prescribe a hormonal drug.
To stop lactation, the drug is prescribed a daily dose of 20 mg in the period from the 1st day to the 3rd day; a dose of 15 mg from the 4th day to the 7th day; dose of 10 mg from the 8th day to the 10th day.
Norkolut side effects
In clinical trials, disorders in the body were rarely observed, which were manifested by headache, tension of the mammary glands, acyclic spotting, paresthesia. In some patients, weight increased, fatigue increased, and peripheral edema appeared. Allergic reactions are possible, which are manifested by a rash and itching.
Dyspeptic symptoms were accompanied by nausea and vomiting.
Thrombosis and thromboembolism were observed only in those patients who took norethisterone for a long time.
"Norkolut", instructions for contraindications
Do not prescribe the drug:
during the maturation of the reproductive system;
with malignant tumors of the mammary gland and suspicions of them;
malignant tumors of the female genital organs;
pregnancy
jaundice
liver diseases;
kidney disease;
hyperbilirubinemia;
tendency to thrombosis;
acute thrombophlebitis or thromboembolism;
bleeding from the urinary tract;
pregnant cholestic jaundice or pruritus;
obesity;
herpes;
hypersensitivity to the components of the drug.