The preparation "Metoprolol" refers to instructions for use in the group of cardioselective beta-blockers with antiarrhythmic, hypotensive and antianginal effects. Taking this medication allows you to slow down AV conduction in a relatively short time, reduce the automatism of the sinus node, excitability and contractility of the myocardium, as well as reduce heart rate, cardiac output and myocardial oxygen demand. In addition, the cardioselective drug Metoprolol, the price of which is about fifteen to twenty rubles, effectively suppresses the stimulating effect of catecholamines on the heart during psychoemotional and physical exertion. As for the main pharmacokinetic characteristics of this drug, its highest plasma concentration begins to be noted after about one to two hours, and the so-called half-life is on average from three to seven hours.
The
antihypertensive drug "Metoprolol" is issued (instructions for use are always included) in the form of round tablets of a creamy white tint and in the form of a solution intended for subsequent intravenous administration. The composition of this cardioselective drug as an active ingredient includes metoprolol tartrate. The tablets additionally contain lactose monohydrate, microcrystalline cellulose, povidone, calcium stearate, talc and crospovidone.
To use the antianginal and antiarrhythmic drug Metoprolol, the manufacturer's instructions for use recommend for the treatment of patients who suffer from angina pectoris (including post-infarction), hypertension and arrhythmia (including supraventricular type tachyarrhythmia). In addition, quite often, doctors prescribe this antihypertensive drug in order to prevent migraine attacks. As part of the complex treatment of thyrotoxicosis, it is also recommended to start taking the cardioselective drug Metoprolol. Indications for use include supportive therapy after myocardial infarction. In this case, the treatment regimen in each case is set solely by the doctor based on the analysis.
As for the list of main contraindications for taking this cardioselective drug, then in the first place it should be highlighted hypersensitivity to metoprolol tartrate, as well as an allergic reaction to any of the auxiliary components. People with heart failure, atrioventricular block, severe
sinus bradycardia, or
sinoatrial blockade should also not take the
anti-arrhythmic drug Metoprolol. Instructions for use also do not recommend prescribing this
antihypertensive drug for weak sinus node, disturbances in the peripheral circulation system or arterial hypotension. With great care, it is necessary to use this medicine in case of hyperthyroidism, diabetes mellitus, bronchial asthma, pheochromocytoma, hypoglycemia, myasthenia gravis, emphysema, psoriasis, metabolic acidosis, non-allergic bronchitis or depression.