With eye diseases, the drug "Levomycetin" is often used. For the eyes, this is one of the most effective means of overcoming the action of harmful microorganisms. Drops contain a 0.25% solution of chloramphenicol, which is the main active ingredient of the drug. Levomycetin, as a rule, is produced by manufacturers in bottles containing 5 ml of active substance, a dropper cap is also in the package package.
The drug "Levomycetin" (eye drops) is described by the instructions as an antibiotic that can be used in the treatment of a wide range of diseases. It has an antimicrobial effect.
Chloramphenicol has properties that provide a bacteriostatic effect and high activity of the drug against a number of gram-positive and gram-negative bacteria: Staphylococcus spp., Neisseria gonorrhoeae, Shigella spp. and others. The substance is also active against strains that are traditionally resistant to penicillins. On the other hand, the resistance of harmful microorganisms to chloramphenicol is formed very slowly.
The pharmacokinetic properties of the drug "Levomycetin" (eye drops), the instruction characterizes as follows. When taking the drug, its components are rapidly and almost completely absorbed from the digestive tract. Moreover, its bioavailability reaches 80%. The drug has the ability to quickly spread in the body. The level of binding of chloramphenicol to plasma proteins is 50-60%, and its metabolism occurs in the liver. The half-life of the main active drug is approximately 1.5-3.5 hours, and excretion is carried out mainly with urine.
The drug "Levomycetin" (eye drops), the instruction recommends taking in case of infectious and inflammatory diseases that are caused by microorganisms sensitive to chloramphenicol. This is, first of all, typhoid fever, dysentery, whooping cough, trachoma. An effective drug in the treatment of pneumonia, meningitis and other infectious lesions.
In the treatment of purulent lesions of the skin, furunculosis, trophic ulcers and burns, as a rule, the drug is used as an external agent. For topical use, the drug is indicated in the treatment of ocular inflammatory diseases.
When prescribing the drug, an individual dosage regimen is recommended. For adults, the dose of the drug is 500 milligrams with three to four times a day. For children, differential use is recommended, depending on the weight of the child and his age.
For children under 3 years, the recommended dose is 15 milligrams per 1 kg of weight, for children from three to eight years old - 150-200 mg, and for older children, the dose is 200-400 milligrams. In all cases, the medicine should be taken three or four times within 7-10 days.
For external use, the medicine is applied to gauze swabs or directly to the affected area. Dressings in this case are made with a frequency of 1-3 days.
The instruction of chloramphenicol (eye drops) is recommended for use in the treatment of ophthalmic diseases in a complex of therapeutic treatment.
This drug may cause side effects. The instruction indicates the possibility of aplastic anemia, nausea, vomiting, headaches can often be recorded. In rare cases, confusion, delirium, and various hallucinations that caused Levomycetin eye drops were observed. Reviews of patients who took this drug suggest that during the reception skin rashes and other external irritations may occur.
You should not take the drug to people who are diagnosed with blood and skin diseases, pregnant women and children under three years of age.
Particular care should be taken in the use of this drug for patients who have previously undergone treatment with cytotoxic drugs, as well as radiation therapy sessions.
With simultaneous use with penicillins, chloramphenicol inhibits their bactericidal effect.