Deviations in the work of the cardiovascular system may indicate the development of a serious ailment. When the first unpleasant symptoms appear, you should seek help from a specialist. The doctor will prescribe a drug that can improve the patient's condition and stop the negative dynamics of the disease. The medicine "Etatsizin" (tablets) is popular. Before using the medicine, you should carefully study the instructions.
Release form and composition
The medicine is presented in the form of yellow round coated tablets. The active ingredient is diethylaminopropionylethoxycarbonylaminophenothiazine hydrochloride. As auxiliary components, calcium stearate, sucrose, methyl cellulose, as well as potato starch are used. The shell consists of substances such as carnauba wax, dye quinoline yellow, magnesium basic hydroxycarbonate, titanium dioxide, and also silicon dioxide. Etatsizin tablets go on sale in cardboard packaging. The medicine is dispensed in pharmacies only by prescription. This reduces the risk of using the medicine without prescribing a specialist.
Tablets belong to the class of
antiarrhythmic drugs. The main active component slows down the excitation process along the myocardial conduction system. At the same time, the fibrillation threshold rises. The drug "Etatsizin" has a significant advantage. Doctors' reviews show that pills have virtually no effect on reducing heart rate.
Pharmacokinetics
The bioavailability of the drug is 40%. The Etatsizin tablets are quickly enough absorbed from the gastrointestinal tract. Reviews of doctors show that the maximum concentration of the active substance in the blood is achieved after 2-3 hours. The medicine may bind to blood proteins. The main components easily penetrate the placenta and can be excreted in breast milk. Therefore, the use of the medication is not recommended during pregnancy and lactation.
The drug Etatsizin is actively metabolized through the liver. Analogues of the drug act in the same way. Some metabolites that form during treatment may have antiarrhythmic effects. The main components are excreted in the urine. The whole process takes no more than 4 hours.
Indications
It is used only as prescribed by the doctor, the medicine Etatsizin. Analogs should also be used only after consultation with a cardiologist. Medicines from this group are prescribed for people with diseases of the cardiovascular system. Most often, the medication is used for deviations such as ventricular and supraventricular tachycardia, supraventricular and ventricular extrasystole, as well as paroxysms of atrial fibrillation and atrial flutter.
People with
liver failure may also be prescribed this drug. In this case, treatment should be strictly under the supervision of a doctor in a hospital. But the use of "Etatsizin" in complex impaired renal function is undesirable. In any case, the decision on the appointment of tablets is made by a specialist after a complete examination of the patient's body condition.
Contraindications
Instructions for use should be carefully studied on the medicine "Etatsizin". Analogs also require increased attention from the patient. The fact is that drugs from this group have many contraindications. They should be known in order to avoid the development of side effects. Tablets are not prescribed for such abnormalities of the cardiovascular system as cardiogenic shock, conduction disturbances, post-infarction cardiosclerosis, severe left ventricular myocardial hypertrophy, as well as chronic heart failure.
A serious contraindication is expressed deviations in the functioning of the kidneys and liver. In some cases, the doctor may make an exception. Pills are prescribed if the benefit of the treatment exceeds the potential harm to other body systems. The decision is made after a complete examination of the patient.
The drug is not prescribed for women who are breastfeeding or bearing a fetus. There are also age restrictions. Etatsizin tablets are not prescribed for minors. With caution, the drug should be used for people with a tendency to allergic reactions. In some cases, hypersensitivity develops.
special instructions
The arrhythmogenic medication Etatsizin may act. Analogs have the same effect. Therefore, patients should strictly study the contraindications for use, as well as pre-clarify the presence of hypokalemia. It is not recommended to use a medication in combination with other antiarrhythmic drugs. For patients with complex diseases of the cardiovascular system, it is advisable to start the course of treatment in a hospital, under the supervision of a doctor. If the doctor notices the positive dynamics of the disease, further therapy can be carried out at home.
In a number of conditions, for example, with an increase in ectopic ventricular complexes, it is necessary to immediately stop taking Etatsizin tablets. Analogs should also not be used in this case. A serious violation is also considered the development of bradycardia or the appearance of blockades.
During treatment, the patient should be under the supervision of specialists inpatient or outpatient. It is strictly forbidden to take alcoholic beverages at this time. In a negative way, the dynamics of the disease can also be affected by smoking or the use of products that increase blood pressure (dark chocolate, coffee).
Taking the drug "Etatsizin", do not get behind the wheel of a car or control other technical means. There is a risk of dizziness and loss of consciousness.
Dosage
The medicine is taken orally, regardless of the meal. However, experts note that the bioavailability of the drug increases when used on an empty stomach. It is necessary to take one tablet 2-3 times a day. If a specialist observes the weak dynamics of the disease, the dosage is slightly increased. The maximum daily allowance is 300 mg (six tablets). The daily dosage can be divided into three doses.
As soon as a stable antiarrhythmic effect is achieved, the dosage is reduced to a minimum. The course of treatment can last no more than a month. If necessary, therapy can be repeated after several weeks.
Overdose
Acceptance in a large number of Etatsizin tablets can lead to unpleasant symptoms. Analogous reviews in this regard also have negative ones. Improper use of antiarrhythmic drugs can lead to the opposite effect. Problems of the cardiovascular system are only exacerbated. In addition, unpleasant symptoms may occur such as disorders of the gastrointestinal tract, dizziness, sleep disturbances, decreased blood pressure.
To eliminate any manifestations of an overdose, symptomatic therapy is carried out in a hospital. Acceptance of the medicine "Etatsizin" is temporarily stopped.
Drug interaction
The medication should not be taken in conjunction with other antiarrhythmic drugs. Do not use tablets in conjunction with drugs such as Propafenone, Allapinin, Disopyramide, Procainamide. It is not recommended to take the medication also in conjunction with MAO inhibitors. If you use tablets "Etatsizin" together with beta-blockers, the antiarrhythmic effect is enhanced. This feature is often used by cardiologists in their practice. Especially good results are given by such a technique in relation to arrhythmia caused by excessive physical exertion.
It is not recommended to take alcohol with the drug. Such a contraindication is described in the preparation "Etatsizin" instruction. Reviews of doctors make it possible to understand that alcohol only exacerbates the patient's condition. It is strictly impossible to take alcohol tinctures with antiarrhythmic drugs.
Analogs
Finding the right medicine at the pharmacy is not always possible. How to replace the drug "Etatsizin"? A photo of one of the analogues is presented below. Information about them can provide a cardiologist. Good results in the treatment of arrhythmias are given by Amiodarone. These are white coated tablets. The main active ingredient is amiodarone hydrochloride. Additionally, components such as povidone, corn starch, lactose monohydrate, magnesium stearate, colloidal silicon dioxide, and sodium carboxymethyl starch are also used. The drug goes on sale in cardboard packaging.
The medicine can be prescribed for arrhythmias of various degrees. Contraindications exist the same as with Etatsizin tablets. Instructions for use, reviews - all this needs to be studied before the start of therapy. The drug "Amiodarone" is not prescribed for children, as well as for women during pregnancy.
Such drugs as Cordaron, Sedacoron, Amiocardin also cope with arrhythmia.
How much is the drug?
The drug belongs to mid-range drugs. For one package (10 tablets) you will have to pay about 1,500 rubles. It is worth remembering that in pharmacies, medication is dispensed only by prescription. You can save if you buy the drug in online pharmacies. There you can buy tablets for 1200 rubles.
What do patients say about Etatsizin tablets?
Patients note that tablets give good results only if taken correctly. It is necessary to strictly observe the dosage prescribed by the doctor and observe the reactions of the body. If any unpleasant symptoms appear, you should immediately contact a cardiologist.
Negative reviews are largely due to the fact that patients inattentively study the instructions. There are a huge number of contraindications that must be taken into account. Before starting therapy, it is recommended to undergo a full examination of the body. In the most difficult cases, treatment should take place in the intensive care unit under the supervision of specialists.