"EsCordicor" is a medicine with antianginal and hypotensive effects. It is considered a calcium channel blocker. Produce medication in tablets. They have a flat shape with beveled edges, yellow. The drug is packaged in blisters of 10 pieces. A total of 30 or 50 tablets.
EsCordicore has in its composition:
- amlodipine besilate;
- lactose;
- cellulose;
- silica;
- primellose;
- magnesium salt of stearic acid;
- iron oxide.
What reviews and analogues does EsCordicore have?
Useful properties of the medication
EsCordicor has an antianginal and hypotensive effect. The drug has a long antihypertensive effect, which is provoked by a vasodilating effect on smooth muscles of the walls of blood vessels. The use of a single concentration of EsCordicor in patients with arterial hypertension leads to a decrease in blood pressure within 24 hours.
The onset of action is observed approximately 2-4 hours after the use of the drug, the duration of the effect is 1 day. After oral administration of a single dose, amlodipine is absorbed from the stomach and intestines.
Indications and contraindications
EsCordicore, the analogues and instructions of which we are considering in the article, is prescribed to eliminate high blood pressure. Prohibitions on the use of the drug:
- Diabetes.
- Severe hypotension.
- Angina pectoris.
- Pregnancy.
- Extreme degree of left ventricular failure.
- A life-threatening condition characterized by a decrease in blood pressure and a deterioration in the microcirculation of vital organs.
- Minor age.
- Breast-feeding.
- Increased Sensitivity.
- Cardiopalmus.
- Impaired liver function.
Instructions for use
The drug "EsCordicor" is taken orally. The initial concentration of the drug is 2.5 milligrams once a day. If necessary, to achieve proper control of blood pressure, it is possible to increase the dose to the maximum, which is 5 mg once a day.
Adverse reactions
The drug "EsCordicor" provokes certain negative manifestations, for example:
- migraine;
- dizziness;
- drowsiness;
- malaise;
- tremor;
- sleep loss
- asthenic condition;
- cramping
- paresthesia;
- depressive disorders;
- loss of consciousness;
- lethargy;
- memory loss;
- ataxia;
- hyperemia;
- palpitations
- vasculitis.
The drug, according to doctors and patients, can additionally cause a number of negative effects:
- dystrophic change in the articular cartilage of a non-inflammatory nature;
- arthralgia;
- muscle pain;
- a condition in which frequent urination occurs during the day;
- deterioration in potency;
- violation of the urination process;
- gagging;
- dry mouth
- bloating;
- violation of taste;
- inflammatory and dystrophic changes in the gastric mucosa;
- rashes;
- hair loss
- thirst;
- conjunctivitis;
- increased sweating;
- backache.
Generics
The following substitute drugs are the analogues of EsCordicore:
- Amlodipine.
- Amlorus.
- "Normodipine".
- "Phenigidin".
- Amlodifarm.
- Nimotop.
- Amlodac.
- "Lerkamen".
- Tenox.
- Nifedipine
- Amlokard.
- Azomex
- Norvask.
- "Felodip."
- Plendil.
- Adalat.
- Corinfar.
- Zanidip.
If a change of medication is required, it is important to contact a medical institution for advice. Next, the most effective antihypertensive drugs will be considered.
Norvask
Modern antihypertensive agent based on amlodipine. The drug is prescribed for high blood pressure, as well as angina pectoris. A single daily concentration of "Norvask" with hypertension stabilizes blood pressure during the day, both in a standing position and lying down. The price of the drug ranges from 400 to 1100 rubles.
Regular exposure to the drug does not lead to a sharp decrease in blood pressure. In a patient with angina pectoris, a one-time daily concentration of the drug increases the time period of possible physical exertion.
According to the instructions of this EsCordicore analogue, it is known that the active substance prevents the occurrence of angina pectoris, and also reduces the frequency of seizures.
Nifedipine
Tablets belong to the therapeutic group of calcium channel blockers. They are used in the complex treatment of various cardiovascular diseases, which are accompanied by high blood pressure.
According to the instructions for use of the EsCordicore analogue called Nifedipine, it is known that it is evenly distributed throughout the body’s tissues and also excreted in milk during breastfeeding.
After using the drug, the active component is quickly and completely absorbed into the general bloodstream from the lumen of the small intestine. After using food, the bioavailability of the drug increases.
The active component of Nifidipine is concentrated in the liver with the formation of inactive decay products that are excreted in urine. The half-life is 24 hours. The drug does not accumulate in the body. This analogue is cheaper than EsCordicore, its cost ranges from 30 to 60 rubles.
"Lerkamen"
The drug is used to lower blood pressure in hypertension or other heart disease, which are accompanied by arterial hypertension.
"Lerkamen" leads to an expansion of the lumen of the arterial bed and a decrease in the level of total blood pressure. the medication does not have any effect on the functioning of the heart and the frequency of its contractions.
After taking the medicine, the active substance is rapidly and completely absorbed into the bloodstream. It is evenly distributed in the tissues of the body. Lercanidipine hydrochloride is metabolized in the liver with the formation of inactive decay products, which are eliminated by the kidneys and intestines in equal proportions.
Before you start using the drug "Lerkamen" you need to carefully read the instructions. There are several features that you should pay attention to:
- A medication can interact with a huge amount of drugs from other pharmacological groups, therefore, when using them, it is necessary to warn the doctor about this.
- With extreme caution, Lerkamen can be used for diseases of the liver and kidneys.
- The simultaneous use of alcohol and the drug is prohibited, as this can lead to severe drowsiness.
Pills in a pharmacy are available on prescription by a healthcare professional. The cost of the drug varies from 300 to 1400 rubles.
"Phenigidin"
With the simultaneous use of a medication with tricyclic antidepressants, as well as diuretics and Ranitidine, the likelihood of negative reactions from the side of the heart and blood vessels increases. With the simultaneous use of drugs with nitrates, the likelihood of tachycardia in the patient and a decrease in blood pressure increases.
If it is necessary to combine Phenigidin with beta-blockers, special care must be taken, since such an interaction increases the risk of arterial hypotension and acute vascular insufficiency.
Patients under the age of eighteen are prohibited from using Phenigidinum. During drug therapy, it is not recommended to take alcoholic beverages, since the simultaneous use of the drug with ethyl alcohol increases the likelihood of severe adverse reactions from the heart, blood vessels, and nervous system.
During treatment with Fenigidinom, it is necessary to refuse to drive vehicles due to possible severe dizziness, as well as drowsiness.
"Normodipine"
Amlodipine-based antihypertensive drug. "Normodipine" is prescribed for hypertension, as well as angina pectoris.
Coronary heart disease is eliminated in two ways:
- The active substance dilates arterioles. With the help of which the peripheral vascular resistance decreases with a constant heart rate. Subsequently, energy consumption decreases and the need for oxygen in the heart muscles decreases.
- The EsCordicor analogue contains an active component, amlodipine, which dilates the coronary and peripheral arteries in ischemic and normal areas of the myocardium. Due to this, the myocardium is supplied with oxygen in people with angina pectoris.
Treatment of people of retirement age with the drug should be carried out under the supervision of a doctor. During the entire treatment, patients should maintain oral hygiene and regularly undergo examination in the dental office. Such measures are necessary to prevent bleeding, as well as soreness and destruction of the gums. The price of the drug ranges from 300 to 800 rubles.
Amlodipine
The drug has a blocking effect on calcium channels. With the development of angina pectoris, Amlodipine reduces the severity of ischemia, improves the supply of oxygen to the heart muscles. "Amlodipine 5 mg" is an analogue of "EsCordicore" and one of the effective medications that perfectly lowers high blood pressure.
The antihypertensive effect of the drug is caused by a direct vasodilating effect on vascular smooth muscles. In people who suffer from hypertension, when taking a single dosage of the drug during the day, there is a strong decrease in blood pressure.
The occurrence of orthostatic hypotension when using the drug is a rare occurrence. The cost of the drug varies from 30 to 190 rubles.
Conclusion
According to reviews, all of the above drugs effectively lower blood pressure in people with first-degree hypertension. In most patients, with a constant intake of even a low concentration of these drugs, it is possible to reduce and normalize the pressure. According to experts, antihypertensive drugs improve well-being, eliminate dizziness, and also help eliminate weather dependence.