Surely, every person has encountered such a skin disease as acne. According to experts, this is an inflammatory disease that is caused by changes in the so-called pilosebial structures.
Acne usually consists of a sebaceous gland and a hair follicle and brings a lot of discomfort to the patient. In this regard, a huge number of different drugs have been developed to get rid of acne. One of them is “Duac” (acne gel). Reviews about this medicine are presented below.
Packaging and composition
What does “Duac” (acne gel) contain? Reviews claim that the composition of the medication includes benzoyl peroxide and clindamycin. The following components were also used for the gel production: carbomer, purified water, disodium lauryl sulfosuccinate, poloxamer, disodium edetate, colloidal silicon dioxide, water, glycerin, dimethicone and sodium hydroxide.
On sale, this drug can be found in tubes of 15 g.
Features of the tool
What is remarkable about the “Duak” medication (acne gel)? The active substance of this agent (clindamycin) is an antibiotic (lincosamide), which bacteriostatically acts against anaerobic microorganisms and aerobic bacteria (gram-positive). By binding to the 23 S ribosome subunit (bacterial), this component helps to suppress the early stage of protein synthesis. High concentrations of this ingredient have a bactericidal effect that is directed against sensitive organisms.
Clindamycin treats comedones well in people with acne. After applying the gel, the percentage of fatty acids (free) on the surface of the skin decreases from 14% to 1%.
What role does benzoyl peroxide play in Duac? Acne gel, reviews of which are presented below, thanks to this component, has a keratolytic effect, which is directed against comedones. This substance is oxidizing. It has bactericidal activity.
According to the instructions, benzoyl peroxide is a sebostatic agent. This property allows it to counteract the excessive production of sebum (cutaneous), which is associated with acne.
Adding this component to the gel reduces the potential for the emergence of clindamycin-resistant bacteria.
Kinetics means
Is the Stieffel Duac Acne Gel Absorbed? Gel (customer reviews are mostly positive about this drug) is absorbed through the skin in a minimal amount. The presence of benzoyl peroxide in the composition of the drug does not affect the absorption of clindamycin. Experts argue that the absorption of the first substance through the skin is possible only after its conversion to benzoic acid.
Indications for use of the drug
When is it recommended to use the Duak medication? Acne gel, which everyone can comment on, is used topically to treat an inflammatory condition such as acne.
Contraindications
The drug in question cannot be used with hypersensitivity to its substances and lincomycin. Also, this remedy is contraindicated in the age of 12 years and during breastfeeding.
Instruction manual
This product is intended for external use. For adults and children from 12 years of age, the drug is applied to the affected areas of the integument once a day. Before using the gel, the rashes are thoroughly cleaned and washed with water. The medication should be applied in a small layer until it is completely absorbed.
Continuous treatment with this drug should not exceed 12 consecutive weeks.
Side effects
In the process of using this drug, the patient may experience undesirable effects such as erythema, dryness, peeling of the skin, exacerbation of the disease and itching at the site of application. Sometimes this remedy causes paresthesia and contact dermatitis.
With prolonged use of the drug, resistance may develop, which can cause the development of superinfection.
Special recommendations
Therapy with this agent should be carried out with extreme caution in individuals with ulcerative colitis, atopic dermatitis and regional enteritis.
If side effects occur, the drug should be discontinued.
In some cases, it may take 4-5 weeks of preliminary treatment to achieve a therapeutic effect.
Avoid contact with the medication in the eyes, mouth, eczematous skin and mucous membranes.
The product in question is capable of bleaching colored fabrics and hair.
Stiefel Duac Acne & Acne Gel Reviews
Consumers claim that this drug treats acne well. After its application, all acne disappears. A significant disadvantage of this medication is the presence of a large number of adverse events. When these appear, it is better to refuse the gel.