Why do patients prescribe such a medication as Indopan? Instructions, indications, composition of this medicine are presented below. You will also learn about what properties are inherent in it and whether it has contraindications.
Form, composition
What does Indopan contain? Instructions for use inform that indomethacin is part of this medication. Currently, the drug in question is not available in pharmacy chains. However, there are many other drugs that contain the same active element. As a rule, they are available in the form of dragees, capsules, injection, tablets, rectal suppositories, etc.
Drug action
How does a remedy like Indopan work? The instructions for use claim that it is a non-steroidal anti-inflammatory drug. It is a derivative of indoleacetic acid and has an antipyretic and analgesic effect. This effect of the drug is due to the indiscriminate suppression of COX2 and COX1, which regulate the synthesis of Pg. In addition, this medicine exhibits antiplatelet properties.
Indications for admission
In what cases is the patient prescribed Indopan medication? The instruction (the indications of this medicine will be presented right now) states that the drug in question is used for:
- Pain syndromes: toothache and headache (including menstrual syndrome), lumbago, myalgia, sciatica, bursitis, neuralgia, tendonitis, pain after injuries and surgical interventions that are accompanied by inflammation.
- Degenerative and inflammatory diseases of the musculoskeletal system: juvenile chronic, psoriatic and rheumatoid arthritis, ankylosing spondylitis, arthritis in Reiter and Paget's disease, neuralgic amyotrophy, gouty arthritis, rheumatism.
- Inflammatory diseases of the pelvic organs, including non-closure of the botallal duct and adnexitis, algodismenorea, pericarditis, Barter syndrome, childbirth.
- Feverish syndrome with paracetamol and ASA inefficiencies.
- Infectious and inflammatory diseases of the ear, throat and nasopharynx with severe pain (for example, tonsillitis, pharyngitis, otitis media).
Contraindications
Which patients should not use Indopan? The instruction claims that this tool is contraindicated in:
- “Aspirin” triad, hypersensitivity, gastrointestinal ulcer, ulcerative colitis, color vision impairment, bleeding, congenital heart defects
- diseases of the optic nerve, liver cirrhosis with portal hypertension, bronchial asthma, arterial hypertension, heart failure, edema, coagulation disorder, liver failure;
- hearing loss, chronic renal failure, hematopoiesis, breastfeeding, pathologies of the vestibular apparatus, pregnancy, glucose-6-phosphate dehydrogenase deficiency.
It should also be noted that for rectal administration, preparations with indomethacin should not be used for bleeding, proctitis, hemorrhoids and in children under 14 years of age.
With caution, this medicine is prescribed for hyperbilirubinemia, parkinsonism, thrombocytopenia, epilepsy, depression, in childhood and old age.
The drug "Indopan": instructions for use
You can use this medication in different ways, depending on the form of release.
Inside, this product should be taken during or after a meal, washed down with cow's milk. For adult patients, the medicine is prescribed in an initial dosage of 25 mg three times a day. With a weak severity of the therapeutic effect, the indicated amount of the drug is increased to 50 mg with the same multiplicity.
For the treatment of acute conditions, as well as for the relief of chronic processes, the medication is administered intramuscularly at 60 mg twice a day. The duration of this course is two weeks.
As for rectal suppositories, they are used after the release of the intestine, into the rectum 50 mg three times a day, or 100 mg before bedtime. The maximum daily dosage of such a drug is 200 mg.
Adolescents over 14 years of age are prescribed this drug at 1.5-2.5 mg / kg per day.
Adverse reactions
The drug "Indopan", the instructions for use of which were indicated above, can cause unwanted effects such as:
- NSAIDs-gastropathy, headache, abdominal pain, insomnia, nausea, agitation, vomiting, irritability, heartburn, excessive fatigue, decreased appetite, dizziness, diarrhea, depression, impaired liver function, ulceration of the gastrointestinal mucosa;
- drowsiness, taste disturbance, peripheral neuropathy, impaired renal function, hearing loss, proteinuria, tinnitus, hematuria, diplopia, development of CHF, blurred visual perception, interstitial nephritis, corneal opacity, nephrotic syndrome, conjunctivitis;
- tachyarrhythmia, necrosis of the papillae, edematous syndrome, bleeding in the gastrointestinal tract, increased blood pressure, anemia, itching of the skin, leukopenia, agranulocytosis, thrombocytopenia, itching of the skin, eosinophilia, aggravation of hemorrhoids, agranulocytosis, leukopenia, thrombocytopenic purpurea;
- severity in the anorectal region, urticaria, hyperglycemia, angioedema, glucosuria, bronchospasm, thrombocytopenia, aseptic meningitis and others.