Medication "Vazilip" application instructions refers to lipid-lowering drugs (used to lower cholesterol). The main component, simvastatin, is involved in the synthesis of cholesterol by the liver cells. is he
reduces the content of said substance in general,
serum triglycerides and low density lipoproteins. Means “Vazilip” (instructions for use indicate this), among other things, normalizes the function of endotheliocytes, during the atherosclerotic process it slows down migration, cell proliferation, and acts as an antioxidant.
Indications for appointment
The medicine "Vasilip" is used for hyperlipidemia, both primary and hereditary (polygenic and heterozygous hypercholesterolemia, mixed and monozygous hyperlipidemia). The drug is also used in case of coronary disease, when the total level of cholesterol in the blood rises.
Release form and composition
The manufacture of the medication is in the form of tablets intended for oral use. One tablet includes the active ingredient in an amount of 10, 20, 40 mg. Additional components are citric acid, titanium dioxide, hypromellose, magnesium stearate, lactose monohydrate, ascorbic acid, starch, propylene glycol, microcrystalline cellulose, butyl hydroxyanisole.
Method of use
In case of hypercholesterolemia, the “Vazilip” remedy is recommended for use once a day (in the evening) in the amount of 10-80 mg. The initial dose is 10 mg, after a month's intake it is gradually increased. The highest daily dose is 80 mg. You can drink tablets
regardless of food. In case of hereditary hypercholesterolemia (homozygous), the dosage per day is 40-80 mg. In coronary artery disease take medication "Vazilip" instructions for use initially recommends 20 mg per day. The highest daily dose is 40 mg. Patients with renal failure in severe form are recommended to take no more than 10 mg of the drug per day. Increasing the dosage is allowed only if there is a strong need and only on condition that the doctor will constantly monitor the treatment process.
Side effects when using the drug "Vazilip"
Patient reviews report good tolerability of the drug. However, some have reported unpleasant effects while using the drug, such as nausea, pancreatitis, constipation / diarrhea, abdominal pain, depression, headache, sleep disturbances, peripheral neuropathy, high fatigue, muscle weakness and dermatomyositis. In very rare cases, rhabdomyolysis develops. Allergic reactions may occur: vasculitis, skin rash, eczema, redness of the skin, angioedema. Usually, all of these negative phenomena, if they appear, then have a low severity and pass quickly.
Contraindications
In acute liver diseases, high sensitivity to the ingredients included in the composition, the medicine "Vasilip" is not prescribed. Also, it is not used by pregnant and lactating women.