Sorbifer Durules, by its pharmacological group, refers to antianemic iron-containing drugs. The medicine is often used to treat anemia that occurs against the background of insufficient intake of iron in the body or a violation of the process of its absorption.
Composition, pharmacological forms
According to the instructions "Sorbifer Durules" is available in the form of tablets intended for oral use. The tablets have a round, convex shape on both sides, yellow. The preparation contains several active components at once: 300 mg of iron sulfate, 60 mg of ascorbic acid.
As auxiliary components in the composition of “Sorbifer Durules” the following are used: polyethene in powder form, paraffin wax, hypromellose, magnesium stearate, carbomer, titanium dioxide. The medicine tablets are packaged in bottles made of dark glass of 30, 50 pieces. Each pack of cardboard contains 1 such bottle.
Pharmacodynamics, pharmacokinetics
As the instructions to the Sorbifer Durules indicate, the main active substances of the medication are able to exert antianemic effects, increase the level of hemoglobin, which is a complex iron-containing protein and performs the physiological function of transferring carbon dioxide and oxygen throughout the body. Iron sulfate takes part in metabolic processes, in the synthesis of heme, which is a structural element of hemoglobin.
In the presence of ascorbic acid, the absorption of iron sulfate in the intestinal lumen and its penetration into the systemic circulation improves. She also participates in the synthesis of red bone marrow cells, which is responsible for the formation and maturation of red blood cells. The components of Sorbifer Durules, after its oral administration, are absorbed quite quickly, spreading through the tissues and being involved in metabolic processes.
Indications for use
The main indications for the use of Sorbifer Durules are:
- Iron deficiency in the human body.
- Iron deficiency anemia (decrease in hemoglobin level, red blood cell count due to iron deficiency).
In addition, the drug can be used to prevent iron deficiency in pregnant women and those in the lactation period, since these conditions are almost always accompanied by a severe iron deficiency.
Also, the drug is popular among blood donors.
Contraindications to the use of the drug
In accordance with the instructions of Sorbifer Durules, there are several physiological and pathological conditions that can become a contraindication to the use of the medication. Among them:
- Changes of an obstructive nature in the hollow structures of the gastrointestinal tract, which can provoke a disturbance in the mixing of the food mass, for example, stenosis of the esophagus canal.
- Pathological conditions that are accompanied by a significant increase in the level of iron in the patient, for example, hemochromatosis, hemosiderosis.
- Violations of the process of utilization of iron ions in a patient suffering from lead, sideroblastic, hemolytic anemia.
- Individual hypersensitivity to any component that is part of the drug.
- Age less than 12 years. Such a ban is due to the lack of a sufficient amount of data indicating the safety of this medication in relation to this category of patients.
It is important to exercise caution when prescribing the drug to patients with concomitant ulcer pathology, which is characterized by the formation of a defect in the walls of the duodenum, stomach, and inflammatory pathologies of the intestine (enteritis, colitis, diverticulitis, Crohn's disease).
Before using the medication, you should consult a specialist and exclude the presence of possible contraindications.
Use of this medication
Let's figure out how to do it right.
Sorbifer Durules tablets are intended for oral use. Do not grind or chew them; it is recommended to drink them with a large amount of liquid.
Adolescents and adult patients are shown to take tablets up to 2 times a day for 1 piece. If the patient has a severe form of iron deficiency or iron deficiency anemia, an increase in dosage is allowed up to 4 tablets, which are taken twice a day.
For prophylactic purposes, pregnant women are shown to take the medicine once a day, 1 tablet of “Sorbifer Durules”, for therapeutic purposes - twice a day, 1 tablet.
On average, the course of use of the drug takes up to 60 days. If the patient regains normal hemoglobin levels, medication may be canceled.
Before or after a meal, take Sorbifer Durules? The drug should be drunk separately from food - 40 minutes before it, 2 hours after it.
Side effects of Sorbifer Durules
When using the drug, patients can develop various negative manifestations on the part of some organs and their systems. Among them:
- Esophageal stenosis, ulcerative lesions of the gastric and intestinal walls, stool disturbance, abdominal pain, periodic urge to vomit, nausea from the gastrointestinal tract.
- General weakness, periodic pain in the head, vertigo from the central nervous system.
- Allergic reactions in the form of urticaria, rash, swelling, specific itching.
In rare cases, hyperemia of the skin may develop. All adverse effects are dose dependent. Therefore, if they occur, it is necessary to stop using the product and consult a doctor in order to adjust the treatment regimen. This is confirmed by the instruction to “Sorbifer Durules”.
Special instructions for the use of the drug
The instructions for using the medication contain a number of special instructions that must be studied and taken into account before starting therapy:
- When using the drug, it is possible that the color of the feces is darkened, which is not a deviation and does not serve as a reason for refusing therapy.
- It is allowed to use the product at any stage of pregnancy, in the lactation period.
- The drug is able to affect the absorption of other medical devices, for example, tetracyclines, penicillamine, levofloxacin, levodopa, methyldopa. In this regard, it is recommended to observe the time interval between the use of these drugs.
- When using medications belonging to the group of antacids, absorption in the systemic circulation of iron is reduced. These funds should be taken with an interval of at least an hour.
- The drug does not affect the activity of the central nervous system and its functionality.
The drug in pharmacies is in free sale, however, its use should be made only if there is an appropriate appointment from a specialist.
Drug overdose
If there is a significant excess of the recommended dosage, the patient may develop symptoms of an overdose of the drug - severe pain in the abdomen, decreased blood pressure, liver damage and NS. Therapy in this condition is symptomatic and should be carried out in stationary conditions.
Analogs of Sorbifer Durules
If necessary, the medication can be replaced by an analog. The most popular drugs are: Fenyuls 100, Ferropleks, Maltofer, Gemofer, Ferrogradumet, Tardiferon.
It is important to remember that each of the specified analogues of Sorbifer Durules has its own list of contraindications, therefore, any replacement of the drug must be approved by the doctor.
The cost of this drug
The average cost of the drug in pharmacies depends on how many tablets are in the package, the region of distribution of the drug, and the price policy of the seller. On average, a package of 30 tablets will cost 380 rubles, containing 50 tablets - 470 rubles.
Reviews on the drug
Most often there are reviews about the use of the drug left by women who took it during pregnancy. They report that hemoglobin due to the use of the medicine returns to normal quite quickly, and negative manifestations (subject to the dosages indicated by the doctor) develop extremely rarely.
The availability of the drug and its affordable cost are separately noted. However, despite all the advantages of the medicine, one should not forget that its use should be agreed with the doctor.