The drug "Wessel Duet F" is a drug that is used to treat angiopathies with an increased risk of thrombosis, circulatory disorders of the brain, circulatory encephalopathies due to hypertension, diabetes mellitus, atherosclerosis. The medicine is used to treat occlusive lesions of peripheral arteries, phlebropathy, nephropathy, retinopathy, neuropathy, diabetic foot syndrome , cardiopathy, thrombotic conditions, antiphospholipid syndrome. The main form of release is capsules.
The drug "Wessel Duet F". Instructions: composition, pharmacokinetics, pharmacodynamics
The drug contains sulodexide, which is an active substance. Auxiliary components: sodium lauryl sarcosinade, triglycerides, silicon dioxide colloid , sodium ethyl paraoxybenzoate, glycerol, titanium dioxide, red oxide, lipoprotein lipase unit.
Almost the entire drug is adsorbed in the small intestine. It is metabolized in the kidneys, liver. The drug is excreted by the kidneys. The half-life is one day.
The medication has pronounced anticoagulant, antithrombotic, angioprotective, profibrinolytic effects. The mechanism of action of the active substance is due to its similarity with antithrombin, a heparin cofactor. Antithrombotic effects are achieved by enhancing the formation of prostacyclin secretion. The fibrinolytic effect is provided by an increase in the content of tissue plasminogen activators and a decrease in the blood of their inhibitors. Angioprotective effects are achieved by restoring the structure and functioning of vascular endothelial cells. The drug restores normal rheological parameters of blood by significantly reducing the concentration of triglycerides.
Pharmaceutical preparation "Wessel Douay F". Instruction: method of application, dosage
The drug is intended for internal use. Dosage - one capsule twice a day between meals. The full duration of treatment reaches forty days. It should be repeated twice a year.
The medicine "Wessel Duet F". Instructions: side effects, contraindications
Possible side effects: nausea, burning, vomiting, allergic reactions (skin rash), pain in the epigastrium.
The drug is not allowed to be used in the first trimester of pregnancy, in the presence of hemorrhagic diathesis, diseases accompanied by a decrease in blood coagulation, and increased sensitivity to components.
Pharmaceutical preparation "Wessel Douay F". Instructions: drug interactions, special instructions, overdose
A significant effect of the capsules of this medicine on the effect of other drugs has not been established.
The drug "Wessel Dou F" during pregnancy can be used in the last two trimesters. During these periods, it can be used as a prophylaxis, treatment of vascular complications (manifestations of gestosis). The drug should be taken simultaneously with the control of the coagulogram. The use of the drug does not cause disturbances affecting the ability to drive various vehicles, dangerous mechanisms.
If the dosage or regimen is not observed, overdose symptoms may occur: bleeding or bleeding. For the treatment of these signs, symptomatic agents are used, and the Wessel Doué F drug is canceled. Analogs of this drug can in this case be a good replacement.