Diseases of the nasopharynx are found in everyone, there is no person who has never experienced problems with nasal congestion and swelling, or a runny nose. Thanks to the development of pharmaceuticals, new products are launched on the market that can comprehensively affect the pathogen that causes the disease. One of these refers to the latest generation of antibiotics - Polydex with phenylephrine. What is it like and how to use it? You can find out about this by reading this article.
Release form
In the pharmacy network, Polydex nasal spray with phenylephrine is sold only in this form, drops or solutions are not provided. For ease of use, the light-tight bottle is equipped with a convenient dispenser-sprayer. The solution itself is transparent.
The composition of the drug
When prescribing any drug, its composition is taken into account, it determines the effectiveness and duration of treatment. Naturally, when it comes to antibiotics, I want to feel better after a short period of use and so that there is more benefit than harm. Studying the instructions for "Polydex" with phenylephrine, you pay attention to the fact that the drug has several active components. This suggests that it is more versatile in terms of combating viruses and pathogenic microbes.
According to the instructions for "Polydex" with phenylephrine, the composition includes substances such as:
- Polymyxin and neomycin sulfate (10,000 units and 10 mg);
- Metasulfobenzoate (250 mcg);
- Phenylephrine hydrochloride (2.5 mg);
- Dexamethasone (0.25 mg).
How the main components work
As indicated in the instructions for use of the spray "Polydex" with phenylephrine, it has a complex effect. One of the active components, which is indicated in the name of the drug, phenylephrine, allows you to remove the swelling of the nose. It also helps to reduce the release of pus from the mucosa of the sinuses. Neomycin acts as an antibiotic that actively fights gram-positive bacteria, and polymyxin - with gram-negative.
The hormonal component of the drug "Polydex" with phenylephrine is dexamethasone, which belongs to the group of glucocorticosteroids. Thanks to this substance, quick regeneration of the damaged mucous membrane, blood vessels, elimination of the allergic reaction and the inflammatory process occurs.
Pharmacodynamics and pharmacokinetics
The main cause of diseases of the paranasal sinuses and nasal cavity is gram-positive and gram-negative bacteria. Thanks to the action of two antibiotics, polymyxin B and neomycin sulfates, it is possible to achieve a stable positive therapeutic effect in the fight against staphylococcus, Escherichia coli, Klebsiella pneumonia, Pfeiffer's bacillus. However, it is worth considering that if the cause of the disease of the nasal cavity is anaerobic and aerobic bacteria, diphtheria, the causative agent of tuberculosis, fungi, and clostridia, then the drug will be ineffective.
The hormonal component dexamethasone, sodium metasulfobenzoate and phenylephrine in combination work with the inflammatory process, and also act as anti-allergenic components. Both ingredients fight the outbreak of harmful microbes, infections.
Indications for use
Due to the fact that the composition of Polydex spray with phenylephrine includes a hormonal component, it is not recommended to use it on your own, without a doctor's prescription. Even if there are all the signs on the face that can be used to judge the possibility of its use, it is important to understand that the causative agent of the infection can be a virus that cannot be defeated by this tool.
You can study the instructions for use of "Polydex" with phenylephrine and understand how much it corresponds to the available indications in a particular case. These include chronic and acute rhinitis, sinusitis, rhinopharyngitis.
In addition to the therapeutic effect, the drug is prescribed for prevention after surgery in the sinuses and nasal cavity. The rationale for the appointment in this case is an obstacle to the development of inflammation and infection.
To whom the drug is contraindicated
The study of the wide scope of Polydex with phenylephrine made it possible to understand which organs and systems of the body are affected by components. Therefore, contraindications are not limited to one or two points. If a person knows that among the obstacles to use there is a disease that he has been diagnosed with, then, of course, you should refrain from taking the drug.
Following the manufacturer's recommendations, contraindications for prescribing Polydex with phenylephrine include:
- Closed glaucoma (suspicion of its formation).
- Taking antidepressants in connection with the risk of developing a hypertensive crisis.
- The first symptoms of a runny nose.
- Albuminuria, which often occurs with kidney disease.
- Angina pectoris, elevated levels of hormones secreted by the thyroid gland, high blood pressure.
The use of this drug is also contraindicated for persons with hypersensitivity to its active components.
Dosage and administration
As a rule, the doctor writes a schedule for the use of Polydex spray with phenylephrine. The instructions also describe the treatment:
- Children from the age of 2.5, as well as adolescents under 18 years old - no more than three times a day.
- Adults - from 3 to 5 times during the day.
The total duration of treatment is determined by the severity of the disease, is regulated by the attending physician, on average 5-10 days. One of the features of the application is the need to warm the solution to room temperature before use. To do this, you can hold the bottle for some time in the palms of your hands.
special instructions
Before the attending physician prescribes "Polydex" with phenylephrine, it must be informed about the existing chronic diseases. This applies to patients suffering from renal failure. A special category includes those who have heart disease, with caution prescribe the drug for hyperthyroidism, arterial hypertension, coronary heart disease.
Since the drug is designed in the form of a spray, it is important to prevent it from getting into the eyes. If this happens, rinse them immediately with warm water. If severe irritation occurs, consult a doctor.
The drug is used strictly according to the instructions for medicinal purposes, they can not rinse the sinuses. The components of the drug do not adversely affect driving.
Conditions for the use of "Polydex" a special category of patients
It should be borne in mind that since there is a hormonal component in the composition, it is not recommended to use the drug for pregnant women during breastfeeding without a reasonable doctor’s recommendation. This is due to the high toxicity of the components of the drug. It can have a negative effect on the fetus and lead to congenital malformations of the hearing organs. In cases where a woman is breastfeeding, the active substances can enter the body of the baby with milk. The child may become lethargic, drowsy, in some cases, tachycardia is noted. The only condition for the use of the drug in this period is the transfer of the child to artificial feeding.
If we talk about children, then the minimum allowable age is 2.5 years. After examining a doctor, the drug is prescribed for the treatment of adenoiditis, inflammatory and purulent diseases of the nasopharynx. In order to determine the dosage and duration of treatment, a complex of studies and the absence of positive dynamics in previous treatment regimens are necessary.
Interaction with other drugs
It is important to know that phenylephrine can have a negative effect (that is, reduce the effect) from taking antihypertensive drugs and diuretics. While taking medications, which include guanethidine, the patient may have dilated pupils. Admission of "Polydex" and cyclopropane in the complex leads to ventricular fibrillation, so it is worth notifying the doctor about taking this drug.
In case antibiotics such as Amikacin, Gentamicin, Monomycin, Streptomycin, Netilmicin have already been prescribed, it is necessary to refrain from the drug until the end of the course of their administration. Simultaneous use can cause problems with the vestibular apparatus, hearing impairment. Since dexamethasone is in the composition, it is not recommended to use “Erythromycin”, “Bepridil”, “Terfenadine”, “Astemizole” and other similar drugs as a treatment, since it negatively affects the work of the heart muscle.
If a patient takes medications with acetylsalicylic acid, antiarrhythmic drugs (Disopiramide, Quinidine, Sotalol) for a long time, then Polydex should be used with caution. During polio vaccination in children, as well as BCG vaccination, it is necessary to refrain from using the spray or make injections only after recovery. This is associated with a high risk of disability and death.
Side effects
Most often, when taking medications, an allergic reaction occurs. This tool was no exception. There may be a burning sensation and itching, urticaria during therapy. As for the nasal cavity itself, in some cases there was a burning sensation and dryness in the nose after injection of the drug. If these feelings cause severe discomfort and become regular, you must consult a doctor to adjust the dosage or treatment regimen.
Analogs
At the moment, there is no such drug that would have an identical composition and could become an analogue of Polydex with phenylephrine. Despite this, there are many other drugs that will be cheaper and able to cope with the same symptoms. However, it should be borne in mind that the specifics of this particular dosage form, due to the complexity of the current disease, it is not suitable for continuous use.
One of the similar products on the pharmaceutical market is Isofra. It has a positive effect in the treatment of rhinitis, rhinopharyngitis, sinusitis, as well as after surgical intervention to prevent the occurrence of the inflammatory process. It can be prescribed to children from the first year of life.
Sofradex is a combined preparation that contains dexamethasone, which is also among the active ingredients of Polydex. If you look at the indications for which it is prescribed, then most often it is a problem with adenoids. In other cases, it is more used to treat diseases of the ears and eyes. It is recommended to use this analogue only after consulting with your doctor.
Avamis has an active ingredient different from Polydex - fluticasone furoate. Age restrictions for use in childhood are the same. Suitable for the treatment of rhinitis, relieves swelling with adenoiditis. Also, for the treatment of these symptoms, "Flikonase", with a similar active ingredient, is suitable. These two drugs, most likely, are even more suitable as an analogue to each other than to the Polydex drug.
Reviews
Those who have repeatedly experienced diseases of the nasal sinuses are aware of the positive effect of Polydex with phenylephrine. Reviews of its properties justify its use at a time when it comes to simple nasal congestion or a cold. Since the components of the drug are quite serious, you should get the approval of a doctor before proceeding with treatment.
Doctors, in turn, resort to this medication only after establishing a final diagnosis, since it has clear indications for use as the main treatment. Moreover, there is a separate category of patients to whom it is categorically contraindicated. We are talking about athletes who, using Polydex, can get positive results from a doping test.
If we talk about the speed of action, then the reviews of patients faced with the need to apply it, speak of a quick result. Swelling of the nose is removed after the first days of treatment, and after a week the disease completely recedes.