The drug "Alpha Normix" is an antimicrobial drug with a wide range of effects. Its main active ingredient is rifaximin, which is included in the group of ansamycins. This drug was obtained using a modification of SV rifamycin.
Features of the bactericidal effect of rifaximin are its ability to irreversibly bind to beta subunits in bacterial enzymes and inhibit the synthesis of RNA and proteins. Because of this, the pathogen, which is sensitive to rifaximin, dies. The instruction to Alpha Normix is presented below.
Pharmacological effect
The drug is based on rifaximin, which is an antibiotic. The main sphere of its influence extends to the elimination of signs of diarrhea and the prevention of the penetration of pathogenic microbes into the body after the operation.
"Alpha Normix" cannot get into the blood, therefore, an overdose is also impossible. It is able to penetrate here only with injuries of the digestive tract and bleeding.
This drug acts primarily in the intestinal lumen. The main method of its influence on pathogens is the inhibition of their reproduction. The drug is included in the chemical process of generating the nutrients required for the microbes and slows it down, thus becoming the cause of their death. "Alpha Normix" eliminates the causative agents of cholera, typhoid fever, salmonellosis, dysentery, eliminates signs of acute food poisoning and diarrhea.
The body accumulates gradually, the concentration is carried out in the intestine, the output occurs during defecation. In accordance with the instructions, this antibiotic is not recommended to be taken simultaneously with alcohol, as the course of inhibition of the nervous system will increase. Apathy, lethargy, and drowsiness may also occur. During treatment with the help of Alpha Normix, you cannot work with any dangerous mechanisms or in the area where a high concentration of attention is required.
The drug helps to get rid of diarrhea that occurs during travel. Since this remedy is an antibiotic, after the therapeutic course, dysbiosis or dysbiosis may occur. This is due to the fact that both pathogenic and partially beneficial bacteria are destroyed in the intestines and stomach, which, in turn, are responsible for the normal digestive process and maintaining optimal microflora in the lower digestive tract.
Alfa Normix cannot be taken along with sorbent agents, as this can cause a weakening of the therapeutic effect. It is better to take it after treatment with antibiotics as one of the rehabilitation courses.
Alpha Normix is also suitable for preliminary preparation for operations in the rectal area and in the peritoneal cavity. Caution is required for people with serious liver and kidney disease.
With a weak resistance of the body to infections of the digestive system, you can use the courses as a preventive measure for half a tablet two to three times a day.
Release Forms
According to the instructions for use, Alpha Normix has such release forms as:
- granules intended for dissolution;
- tablets of two hundred and four hundred milligrams.
Pellets are a universal variety that is suitable for both children and adult patients. Pills should be drunk only after reaching the age of twelve. The drug "Alpha Normix" is forbidden to use in patients with insufficient enzyme activity in relation to glucose, maltose and fructose.
The drug is effective in a disease such as diverticulitis, in which pockets in the intestine are formed, and in turn, pieces of undigested products and feces are packed in them, as a result of which the process of inflammation begins.
The use of Alpha Normix is also prohibited during exacerbations of dysbiosis, as this will worsen the condition of the patient’s body.
Indications for use
The medication can be used for the following purposes:
- to reduce the amount of decomposition products of nitrogen (ammonia) in the intestine;
- to maintain the body's ability to resist chronic diarrhea;
- to eliminate the inflammatory process with diverticulitis;
- with insufficient functioning of the liver;
- to eliminate acute infections of the digestive system;
- with pathologies of the brain of the head (encephalopathy);
- to get rid of diarrhea while traveling;
- during surgical interventions on the organs of the peritoneal cavity.
Dosage of the drug and method of its use
Alfa Normix, in accordance with the instructions, is taken in the following dosage: one tablespoon or tablet of the drug every six hours. It is necessary to precisely follow the schedule of use, since the drug must be supplied to the patient's body constantly in the same doses.
It is advisable to drink the drug for five days. However, with a faster onset of improvement, its use can be discontinued. Before using the medicine, you must always consult a specialist.
This drug in the form of tablets is biconvex, the shell is glazed. It is necessary to swallow them, without absorbing or chewing, with clean water. For these purposes, you can not use alcoholic beverages, tea and coffee.
The suspension must be diluted with warm, clean water. First you need to pour a little water into the bottle and shake it so that the granules completely dissolve. After this, water is added again, and the solution is finally mixed. The bottle is enough for five doses. It can be stored for a week at a temperature of twenty degrees. Then you need to make a new solution, and the old one is not allowed. Alpha Normix should be drunk before or after a meal.
Pregnancy and lactation
In accordance with the instructions for using the drug, you can not take it while carrying a child and breastfeeding, since the drug negatively affects the formation of the bone skeleton of a future baby. This medicine should be taken only after a mandatory consultation with a specialist.
Use for treating children
Since the drug has an extensive list of side effects, it cannot be used to treat children. According to the instructions, with caution, you need to drink it in the following dosage:
- prohibited until the age of two;
- babies from two to twelve years old can drink in the form of a solution once every nine hours for a dessert spoon;
- from twelve years and at an older age, you can drink a solution (one tablespoon) and tablets (one piece) once every eight hours.
If any side symptoms occur, then the medicine is prohibited. Before using the drug in the pediatric area, you must definitely get a specialist consultation.
This is confirmed by the instruction. Analogs of Alpha Normix will be considered below.
Contraindications
The drug has a rather impressive list of contraindications:
- patient age up to two years;
- intestinal obstruction;
- sensitivity to the composition of the drug;
- digestive tract ulcers and internal bleeding;
- chronic renal disease;
- intolerance of complex sugars (glucose, maltose and fructose) by the patient.
Side effects
Side effects when using this drug are as follows:
- shortness of breath and dry mouth;
- dizziness and headache;
- digestive tract disorders and diarrhea;
- pain during urination and itching in the intimate organs;
- skin rashes;
- increase in blood bilirubin;
- loss of appetite, candidiasis and lethargy;
- oppressed state of mind.
The drug reduces the effect of contraceptives.
Alpha Normix: analogues
The closest analogues of this drug are:
- Stopdiar;
- "Furazolidone";
- Phthalazole.
Reviews
The drug has proven itself in the treatment of inflammatory chronic intestinal damage, travelers' diarrhea, complex treatment of liver encephalopathy, prevention of various complications of diverticulitis, etc.
According to reviews, Alpha Normix is well tolerated and very rarely causes adverse effects when used. Both specialists and patients note a high speed of action of this antibiotic.
The disadvantages of the drug are its high cost, as well as the inability to treat children with it until they reach twelve years of age and pregnant women.
In some cases, there is no therapeutic effect, which is most often caused by unjustified use.