Restore nasal breathing will help the drug "Polydex". With sinusitis (reviews say that this medicine treats the most prolonged runny nose for 3-5 days), this remedy is especially effective. It has an antibacterial and anti-inflammatory effect. It contains an antibiotic and should not be used without a doctor's prescription.
Composition and form of release
The drug "Polydex" with sinusitis (reviews claims that the drug can cause side effects and therefore should be used strictly according to the instructions) is quick and very effective.
Available in the form of a spray. Contains such active substances as:
- neomycin sulfate;
- polymyxin B sulfate;
- dexamethasone sodium metasulfobenzoate;
- phenylephrine hydrochloride.
The following components were used as additional components in the preparation: methylparaben, citric acid, polysorbate 80, lithium hydroxide and lithium chloride, macrogol 400, purified water.
The drug is packaged in 15 ml polyethylene bottles with a nebulizer. The medicine is packed in a cardboard box, instructions for use are also enclosed there. It is made in France, by the Lab company. Bouchara Retordati. "
pharmachologic effect
Spray "Polydex" with sinusitis (reviews recommend not using this medication without a doctor’s prescription, since it has a strong effect and has contraindications) is especially effective at the initial stage of the disease. It is a combination drug. Its effect on the body is due to its composition. It has anti-inflammatory, anti-allergic and antibacterial properties.
The drug is actively used in ENT practice, and the antibiotic contained in its composition significantly expands the spectrum of the drug's effect on gram-positive and gram-negative microorganisms that can cause a number of diseases of the nose and paranasal sinuses. When exposed to the nasal mucosa, it injures the membrane of microbial cells, which causes their death, since the flow of metabolites into the cell is disrupted.
Dexamethasone in the composition of the drug refers to glucocorticosteroids. It has anti-inflammatory effect. It suppresses allergic reactions and is characterized by desensitizing quality. It inhibits the release of inflammatory mediators, normalizes the membranes of cell tissue and organelles, and reduces the permeability of capillaries.
Neomycin is characterized by an antibacterial property. Belongs to the group of aminoglycosides. It inhibits the development of anaerobic and aerobic bacteria. Inhibits the effect on the nasal cavity of Pseudomonas aeruginosa and other bacterial infections. It is indispensable in the fight against infections that cause many ENT diseases, such as Klebsiella, Escherichia coli, Staphylococcus aureus, Hemophilus influenza.
Polymyxin actively acts on pathogenic bacteria. Refers to antibiotics. In combination with neomycin, it acts most effectively. Destroys many pathogenic bacteria. Does not affect some types of anaerobes and streptococci.
Phenylephrine - has a vasoconstrictor effect. Several times increases the effect of adrenaline.
The general effect of the Polydex drug has a local glucocorticosteroid, anti-inflammatory, antibacterial and antiseptic effect.
Acting with sinusitis, the drug relieves inflammation, swelling of the nasal sinuses, cleanses and improves breathing through the nose. It fights the effects of pathogenic bacteria. Reduces capillary gaps and promotes abundant excretion of exudate from the sinuses. It cures this disease quickly and after several days of therapy relief comes. In the treatment of sinusitis, it is used in complex therapy, which allows to achieve the maximum effect.
The drug can be used both for the treatment of adults and children.
Indications for use
"Polydex" with sinusitis (reviews indicate the high cost of the drug) is one of the best and most effective drugs. It is indicated for the treatment of infectious diseases and pathologies with inflammation of the nasal cavity, pharynx, and also sinuses. This is rhinopharyngitis, which is in a chronic and acute form, rhinitis, both acute and chronic, sinusitis, frontal sinusitis, sinusitis, and also other diseases of an infectious and inflammatory nature.
Therapy with Polydex usually does no harm to patients, but the medicine should be used only for otorhinolaryngological diseases that take place in a complex form. If a surgical operation was performed on the nasal cavity, then Polydex is prescribed for the prevention of infections and inflammations.
Contraindications
The drug "Polydex" with sinusitis (reviews indicate that the drug showed itself well with green discharge from the nose, quickly removed a protracted runny nose) is quick and effective, but despite this, the use of the medication has contraindications. So, you can not use the drug simultaneously with monoamine oxidase inhibitors. It is forbidden to use Polydex to persons with angle-closure glaucoma and with suspicion of it. You can not use the drug for viral diseases, as well as if there is a pathology of the kidneys with albuminuria. Do not prescribe medication during pregnancy and lactation.
Do not drip the drug in children under the age of 2.5 years. Do not use this medication for people with hypersensitivity to the components that make up the drug. “Polydex” is prescribed with caution in patients with coronary heart disease and arterial hypertension.
Athletes should be careful when using the drug, since the drops contain substances that appear during doping control.
Dosage and administration
Nice has a spray "Polydex" reviews. With sinusitis, its performance is noted, a positive result is visible on the 3-5th day of treatment, an adult population is prescribed one injection in each nasal passage. The drug is used from three to five times a day.
Children in the 2.5-15 year age category need to be injected one jet three times a day. With sinusitis, the dosage recommended above does not change. The therapeutic course lasts 5-10 days.
The spray can not be turned over, and the drug must be injected vertically on inspiration. For one injection, just one click on the side walls of the bottle.
Side effects
Only as prescribed by the doctor should use the drug "Polydex". Reviews for sinusitis note that the process of using the drug may cause side effects in the form of allergic reactions.
Instructions for use with the drug does not recommend combining this medicine with alcohol. Polydex means rarely causes adverse reactions and is well tolerated by patients, especially if the recommended dose was not exceeded when using the drug.
The vasoconstrictor property of the drug in some cases provokes temporary discomfort in the sinuses, which is manifested by burning, itching and dry nose. Allergic rashes on the skin are rare enough.
special instructions
The drug "Polydex" with sinusitis in adults (reviews note the complex composition of the drug and warn that it contains antibiotics) is usually used in complex treatment with other medicines.
Before using this medicine, it should be noted that Polydex is contraindicated in people with renal failure.
The drug can not be used for washing the sinuses.
Caution should be exercised when treating this drug with people with coronary heart disease, hyperthyroidism, and hypertension.
Due to the low degree of absorption, an overdose of this drug is unlikely.
Drug interaction
Polydex nasal spray for sinusitis (reviews indicate the availability of this medicine and say that it is sold in every pharmacy) cleans the sinuses well. Acts quickly and delicately.
The presence of phenylephrine in the composition and gives a drug interaction with other medicines. The combined use of guanethidine and this drug increases the hypertensive property of phenylephrine. This is due to a decrease in the sympathetic tone of guanethidine. Also, with this combination, prolonged mydriasis is possible. If such a combination of components cannot be avoided, then careful medical supervision is necessary during treatment.
The drug "Polydex" with sinusitis
The nasal spray "Polydex" with maxillary sinusitis collected the most positive. Firstly, it helps to combat bacterial microflora and pathogens in the nose due to the antibacterial effect of neomycin and polymyxin.
Secondly, the drug helps relieve the inflammatory process, allergic nasal sinus congestion. This action of the drug provides dexamethasone, characterized by anti-inflammatory and anti-allergic properties.
Thirdly, Polydex successfully eliminates the edema that forms in the nose as the disease progresses, when the small vessels dilate. The resulting edema prevents the exit of fluid from the sinuses. Such substances as dexamethasone and phenylephrine will relieve puffiness and have a vasoconstrictive effect.
In order for treatment of sinusitis to be effective, the following rules should be followed:
- Before using the drug, the nose should be thoroughly cleaned, and after the injection of the drug, you can not immediately blow your nose;
- injecting into one nasal passage, the other must be clamped with a finger;
- do not exceed the therapeutic course without a doctor's prescription;
- after each use of the drug, the dispenser should be washed with water.
When treating sinusitis, it is not necessary to rely only on the action of one spray, it is important to choose a competent comprehensive treatment here.
Efficiency
The Polydex spray has been proven more than once for sinusitis. Reviews about the drug note the possibility of allergic reactions.
This drug has a minimal amount of side effects. According to clinical trials, the spray reduces mucous discharge from the nose by 55%. Eliminates pain in the sinuses and relieves nasal congestion by 60%.
This medicine refers to a new generation of drugs. It is used in special cases, when medicines that are simpler in composition do not help, and the disease has turned into a complex form. The drug should only be used as directed by a doctor.
Analogues of the drug "Polydex" with phenylephrine
Reviews (with sinusitis) indicate a convenient form of release. They note that it is very difficult for him to choose a worthy replacement. The closest in composition is the medication "Maxitrol". It contains polymyxin B, neomycin and dexamethasone. Also very effective in the treatment of sinusitis may be funds: Isofra, Nasobek, Avamis, Flixonase and other drugs.
There are no complete analogues in composition with the Polydex drug with phenylephrine, but the choice of drugs with a similar effect is very wide.
Cost
It is confirmed that doctors almost always prescribe the drug "Polydex" with maxillary sinusitis in children. Instructions for use are included and warns of possible contraindications and side effects. The drug is dispensed from pharmacies with a prescription. It costs from 230 to 300 rubles.
Patient Reviews
High efficacy is noted when using the Polydex medication for sinusitis in children; parental reviews. They say that the medicine works quickly, already on the third day there are green discharge from the nose, and breathing becomes free. The drug shows a good result even with a prolonged runny nose.
The adult population is also quite a spray action. Celebrate its quick effect. They say that almost all diseases of the sinuses pass in 3-5 days. The drug has no taste or smell. Squirts into the nose so imperceptibly that some patients doubt whether the medicine got into the nose or not. Many people note antibiotics as a part, therefore they do not recommend using the medicine without a doctor's prescription.
Patients attributed the disadvantages to the high cost of the medicine, an inconvenient dispenser that needs to be kept only upright, and at the slightest tilt it does not spray the medicine, but dispenses the drug with a stream. In some, the drug caused an allergic reaction. Only a small part of the population claims that Polydex spray did not help them at all, so they had to reconsider their treatment.