In the article, we consider the instructions for use and reviews for the Lespefril preparation.
This drug is a natural herbal preparation, the action of which is aimed at eliminating the symptoms of renal dysfunction. Lespefril improves urination and reduces the concentration of nitrogenous products in the blood (urea and creatinine). As a result, the filtration of liquids in the kidneys is normalized, urea and creatinine are excreted from the body faster, the blood is cleaned of toxic nitrogenous products of protein metabolism. The drug has the ability to enhance diuresis, so it is used for renal failure.
Drug release form
The medicine “Lespefril” is produced in the form of a solution that is intended for oral administration. It is sold in bottles of 100 milliliters.
The composition of this drug
According to the instructions to Lespefril, the following pharmaceutical components are included in the composition of a medicinal product:
- Alcohol tincture of two-color lespedeza - 15 ml.
- Anise essence - 0.25 ml.
- Ethyl alcohol in a concentration of 70% - 84.75 ml.
The active component of the drug "Lespefril" is the tincture of the medicinal plant Lespedeza bicolor.
Analogues of this drug
The analogs of the Lespefril medical device according to the mechanism of action are drugs: Vitaprost, Afala, Prostatilen, Flaronin, Ichthyol, Uroprost, Prostanorm, Bioprost, Superlimfa, Kanefron ”,“ Renell ”,“ Speman ”,“ Tentex ”,“ Flaronin ”and“ Cyston ”. Only a doctor should prescribe a replacement, self-medication is unacceptable.
Pharmacological effects of the drug
As the instructions indicate, Lespefril helps to increase renal filtration, decreasing azotemia and increasing the excretion of nitrogenous toxins in the urine. Thanks to treatment with this drug, diuresis rises and sodium ions are excreted. To a much lesser extent, the removal of potassium ions is carried out.
Therapeutic effect
In accordance with the instructions for the medicine "Lespefril", the therapeutic effect is explained by its chemical compounds. For example, catechins in their type of exposure are similar to vitamin P. That is, they act as vascular protectors that strengthen the walls of the capillaries, preventing the exit of fluid into the tissue and the appearance of edema.
In addition, the drug "Lespefril" can have a rather powerful diuretic effect, which is called a diuretic. The intensification of urinary processes occurs due to the activation of filtration in the renal tubules.
This medication is distinguished by a rather rare and unique property, namely, it acts as a diuretic that preserves potassium. This suggests that under its influence only sodium is washed out of the blood. By the way, a widely known diuretic, also preserving potassium, is a drug called Veroshpiron.
Indications
Lespefril should be taken as directed by a doctor. The main indication for taking this medication is the presence of chronic kidney failure in a person. In this case, the medication in question is used as part of symptomatic therapy.
Dosage regimen
As a rule, this medicine is taken orally at 15 milliliters four times. Dilute this medication with water immediately before use. The course of therapy is usually three or four weeks. A repeated therapeutic course is possible three weeks later and after receiving a doctor’s consultation.
Side effects
Some side effects from the use of Lespefril are possible. For example, allergic reactions are a fairly common occurrence. In more rare cases, we are talking about hyponatremia. In the event that any of the side effects listed in the instructions for the patient are aggravated, or the person notices any other adverse reactions that are not indicated in the instructions, you should inform your doctor.
Contraindications
As the instructions to Lespefril indicate, in the process of using the medication in question, it is necessary, first of all, to pay attention to a number of contraindications. So they are as follows:
- This medicine should not be used during pregnancy, and, in addition, during breastfeeding.
- It is not suitable for treatment if the patient has liver disease.
- It is forbidden to use this medication for alcoholism, and, in addition, against the background of the patient having epilepsy.
- The drug is not suitable for use in cranial and brain injuries.
- It should not be used for diseases of the brain.
- The medicine in question is prohibited under the age of eighteen.
- It should not be used with hypersensitivity to the components.
special instructions
What else does the instruction to Lespefril tell us?
In the case of hyponatremia, this medication should be compensated by the introduction of drugs that contain sodium ions. It should also be borne in mind that this medical product contains at least forty percent ethanol. In the maximum single dosage of the drug, the amount of ethanol can be at least 4.7 grams. As for the maximum daily doses, at least 18.8 grams.
In the process of treatment, it is imperative to be careful while driving, and, in addition, when doing other dangerous activity variations that require an increased concentration of attention along with the speed of psychomotor reactions.
Drug overdose
In case of an overdose, it is quite possible a significant increase in side effects. Therapy in this case is symptomatic.
Drug interaction
Due to the presence of ethanol in the preparation, the use of Disulfiram, sedative medications, monoamine oxidase inhibitors, metformin, insulin and sulfonamide is contraindicated in patients during its use. As part of the co-administration of several drugs at once, it is necessary to take into account the presence of ethanol in the drug, because it can change or enhance the effect of other drugs.
Storage conditions
Store the presented medicinal product exclusively in a dark place. Contain a bottle at a temperature of from fifteen to twenty degrees. Keep it also out of the reach of small children. The total shelf life is three years. This medicine should not be used at the end of this period. The medicine is dispensed without a prescription.
Reviews
In the reviews, people say that this medication is actually very effective in the presence of chronic kidney failure in a person. It is also noted that Lespefril is suitable primarily for symptomatic therapy.
In some reviews, people complain that Lespefril can provoke allergic reactions. In such a situation, experts advise the medication to be replaced with a suitable analogue, of which it has quite a lot.
It is also worth noting that according to reviews, some patients are not happy that this medication is not compatible with insulin and a number of other pharmaceutical substances.
We reviewed the instructions and reviews about the medicine for the Lespefril medication.