For many, the manifestations of allergic reactions are familiar. Someone reacts to the flowering of some plants, to the deterioration of air, water. Some mothers are aware of the baby’s “red cheek syndrome” after eating sweets or food with dyes. In cases of laryngospasm and obstructive allergic bronchitis, antihistamines are prescribed (in combination with some others). Effective in allergic reactions of varying severity is the drug "Eden".
Forms of release of the drug "Eden"
The drug "Eden" is available in several forms. Blue tablets are coated and have a biconvex shape. One tablet contains 5 mg of active ingredient. Usually a package consists of 10 tablets. Also, the drug is available in the form of a syrup, which is used for children. 1 ml of a viscous orange liquid contains 0.5 mg of the active substance.
What are the tablets of this drug made of?
Desloratadine is the active ingredient in the Eden preparation. Tablets and syrup are identical in their effect on the body, viscous liquid is used more for children, and tablets for adults. In addition to the main substance, the preparation also contains auxiliary substances. "Eden" tablets and syrup have in their composition: calcium hydrogen phosphate, lactose, maize starch, used in many preparations of magnesium stearate and in a small amount some others.
Action "Eden"
This medication is effective in countering all kinds of allergic reactions. What it is and what is the effect of the drug, the instruction describes the medicine "Eden". The description of the drug helps to understand exactly how the active substance defeats the manifestation of allergic reactions of the body.
Thirty minutes after taking the medicine, desloratadine can be determined in blood plasma, while its maximum concentration will be reached in about three hours. The half-life will take twenty-seven hours and corresponds to the degree of cumulation. This substance does not cross the BBB (physiological barrier between the bloodstream and the central nervous system). In this case, an intensive metabolism takes place in the liver due to hydroxylation with the formation of 3-hydroxydesloratadine, which binds to glucuronic acid compounds. Only a small portion of the medication that comes out comes with urine.
Fatty and high-calorie foods, alcohol do not significantly affect the distribution of the drug in the body. Explains how to use "Eden" (tablets) correctly, instructions. The price of this drug is quite affordable, and the result, according to reviews, is excellent. The tablets have an antihistamine effect and have an anti-inflammatory effect.
To whom are the Eden tablets indicated?
The drug is a fast-acting agent, since the body does not need to additionally convert loratadine to desloratadine. For systemic use, the Eden tool is used. The instruction for use states that it is effective in allergic reactions, such as polinozny and rhinitic manifestations:
- sneezing
- vasomotor and allergic rhinitis;
- swelling of the mucous membrane and nasal sinus congestion;
- itching in the eyes;
- lacrimation and conjunctival hyperemia (redness of the eyes);
- itching in the palatine region of the sky;
- cough.
In addition, it is indicated and is often used for hives, relieving itching and reducing the size and number of rash elements.
What are the contraindications to the use of the drug?
Eden tablets, instructions for use, this also confirms, are not shown for children and are used from 18 years. For children, you need to use syrup.
The main contraindications are:
- Hypersensitivity to any substance that is part of the drug.
- Intolerance to hereditary fructose.
- Deficiency of the enzyme "Lapp-lactose."
- The presence of glucose / galactose malabsorption syndrome
- The state of gestation (pregnancy) and the lactation period.
As for the interaction with other drugs, it can be noted that there are no clinically significant changes in the plasma concentration of the active substance when using the drug together with Ketoconazole, Erythromycin, Azithromycin, Fluoxetine and some others.
There was also no marked increase in the effect of inhibition of ethanolan psychomotor function if oral tablets "Edem" (edem) are used.
Since there is no accurate data on the enzymes responsible for the metabolism of desloratadine, the possibility of interaction with other drugs of drugs cannot be completely ruled out.
Dosage for children and adults
Children under 18 years of age use the drug in the form of a syrup, depending on the weight and age of the child. In this case, the dosage is prescribed by the doctor.
Adults take one tablet, without chewing, once a day. The tablet must be washed down with plenty of water. The timing of treatment is set by the doctor. It is desirable to take the drug at the same time, regardless of the meal.
Are there any side effects after taking Eden?
As a rule, this drug does not have side effects on the body, since the active substance itself is well tolerated by most patients. Among the possible side effects of the drug, the following are noted:
- Not frequent: fatigue in an increased form, a feeling of dryness in the oral cavity, the detection of headaches after taking the drug.
- Rare: tachycardia, hyperactivity of psychomotor origin, a seizure reaction, dizziness, increased liver enzyme activity, increased bilirubin index, diarrhea, pain in the abdomen, nausea, vomiting, dyspepsia.
- Very rare: detection of a hypersensitive reaction, including anaphylactic, angioedema in the form of itching, swelling, urticaria.
Features of the use of the drug
The instructions for use, the description, indications, as well as contraindications drawn up for the Eden medical preparation, indicate caution in the use of this drug. Indeed, with certain diagnoses, it can dramatically worsen the patient’s health. In the diagnosis of severe renal failure, it is recommended to monitor the indicator of function (indicators of "clearance clearance").
In the prescribed therapeutic dose, the drug does not affect the ability to drive vehicles and work with other mechanisms. If this has been noticed, then the use of the drug should be canceled or stop working with the mechanisms during treatment.
In case of an overdose or accidental ingestion, more than prescribed, it is recommended to wash the stomach, take activated charcoal, and if the condition worsens, therapeutic help is required. The desloratadine component is not excreted by hemodialysis, and the effectiveness of peritoneal removal has not been elucidated.
Eden (tablets) - reviews of doctors and patients, prices
This drug is popular with both specialists and patients. This demand has appeared due to the effectiveness, which is also described by the instruction enclosed in the packaging of the Eden preparation (tablets). The price of this drug is affordable for many allergy sufferers (in the range of 100-200 rubles). Such prices further increase the demand for medicine.
Doctors give preference to this drug, compared, for example, with the drug "Loratadine", since the active substance in it has already been converted to work in the body. When the substance loratadine enters the digestive tract, under the action of enzymes, undergoing chemical reactions, it eventually turns into desloratadine. But this takes precious time, especially if an allergic reaction develops quickly and swelling of the mucous membrane or bronchospasm increases. "Eden" quickly leads a person out of this state, which makes his health easier.
Patients also note the rapid effectiveness of the drug. Many experienced allergy sufferers use only this medicine during periods of exacerbation of the disease. They note that after taking it at dinner by the evening, the manifestation of allergies is reduced. If there is no constant irritant for the body, then after passing the course of treatment the disease does not make itself felt for a long time.