Today we will tell you about what is the drug "Dalacin" (acne gel). Reviews about this tool, its pharmacological properties, method of use and side effects will be described in detail in this article.
The form of the drug, its packaging and composition
In what form can I get the Dalacin acne remedy? Reviews, instructions for this drug say that in a pharmacy it is sold as a 1% gel for external use. This medication goes on sale in 30-gram tubes, which are placed in cardboard boxes. The gel itself is a viscous, colorless and transparent mass.
What is the composition of the drug "Dalacin" (acne gel)? Reviews of experts report that the effectiveness of this drug is due to the presence of an active substance such as clindamycin (in the form of phosphate). It should also be said that the composition of this medication also includes additional components in the form of allantoin, methyl paraben, propylene glycol, polyethylene glycol, 934P carbomer, 40% sodium hydroxide solution and purified water.
Pharmacological action of a medical product
What is the drug "Dalacin" (gel)? Reviews, photos of this tool will be presented a little further. This medication is an antibiotic for topical use, which belongs to the group of lincosamides.
According to studies, after application to the skin, the drug is rapidly hydrolyzed by phosphatases in the ducts of the sebaceous glands, resulting in the formation of clindamycin, which has antibacterial activity.
This medication is indicated for strains of Propionibacterium acnes. This fact explains the effectiveness of the drug during the treatment of acne vulgaris.
After using the drug, or rather, applying clindamycin to the skin, the amount of free fatty acids on their surface decreases from approximately 14% to 2%.
Pharmacokinetics of an antibiotic
Is the external drug Dalacin absorbed? Expert reviews contain information that after applying 1% of the gel, its active substance in urine and blood serum is detected in very low concentrations.
An increased activity of clindamycin in comedones was revealed in those people who have acne vulgaris. The average concentration of an antibiotic in the comedone content for a month is 597 mg / g.
During clinical trials, patients over the age of 65 were not included in sufficient numbers. This fact prevented an objective assessment of whether there are any differences in the pharmacokinetics of the elderly compared with the young.
Indications for use of the gel
What is Dalacin (gel) intended for? Customer reviews say that this tool quite effectively eliminates acne and acne. It is for their treatment that the medication we are considering is intended.
Contraindications to the use of an external gel
In what cases is it not recommended to use the Dalacin acne remedy? Reviews of specialists contain information that this drug is strictly prohibited for use with the following factors:
- under the age of 12 years (information on the effectiveness and safety of the drug is not available);
- antibiotic-associated colitis (including a history);
- hypersensitivity of the patient to the active substance.
The drug "Dalacin" for acne: reviews, instructions for use
According to patient reviews, this medication quite effectively fights against acne on the skin. But before using this drug, you should definitely consult with a specialist. After all, if used improperly, it can cause side effects.
So how should I use the drug "Dalacin" and "Dalacin T" (gel)? Reviews of patients say that there is nothing complicated in using this medication. The gel must be applied only externally. Its thin layer is applied to the affected area (clean and dry skin) twice a day.
To get a visible effect from the use of this drug, gel treatment is recommended to continue for 6-8 weeks. In case of acute need, therapy can be carried out for up to 6 months.
In the event that after the use of the medication for a long time the effectiveness of treatment began to gradually decrease, it is recommended to take a break for a period of 4 weeks.
Overdose
Have there been cases of overdose of the drug "Dalacin"? Reviews of doctors say that with improper and uncontrolled use, this medication can really adversely affect human health.
Symptoms of an overdose may include the following deviations: diarrhea, hemorrhagic diarrhea and pseudomembranous colitis.
How to get rid of the pathological condition that arose during the improper use of the medication from acne and acne? First of all, symptomatic treatment is carried out, and then maintenance therapy.
Side effects of using an external gel
Can Dalacin (acne gel) cause side effects? Reviews of experts say that such a medication sometimes causes undesirable side effects. These include the following:
- Organs: burning sensation in eyes.
- Skin: contact dermatitis, increased production of sebaceous glands, dry skin, urticaria, skin irritation.
- Alimentary tract: pseudomembranous colitis, abdominal pain, colitis, dyspeptic disorders, namely vomiting, diarrhea and nausea.
- Other abnormalities: folliculitis, which can be caused by gram-negative flora.
Interaction with other drugs
Is it possible to use Dalacin (acne gel) with other drugs at the same time? Reviews of specialists contain information that there is a cross-resistance of some microorganisms to clindamycin and lincomycin
I also want to say that between erythromycin and clindamycin antagonism is noted.
Specialists have found that clindamycin is able to disrupt neuromuscular transmission, thereby enhancing the action of other peripheral muscle relaxants. In this regard, the medication must be prescribed with extreme caution to those patients who take the funds of this group.
The period of lactation and gestation
Is it possible to use Dalacin gel during pregnancy? Experts say that in animal studies no negative effects on the fetus were found. The only exceptions are those cases when the drug was used in high doses, toxic to the mother.
As for clinical studies, with the systemic administration of the drug to women in the 2nd and 3rd trimesters of pregnancy, there was no increase in the frequency of congenital anomalies of the fetus. It should be noted that the experience of taking the drug in women in the 1st trimester of pregnancy is absent.
Thus, a medication can be prescribed during gestation only if the potential benefit to the mother significantly exceeds the possible risk to the baby.
To date, it has not been established whether the drug is excreted together with breast milk after its external use. However, one cannot but note the fact that clindamycin is present in breast milk after parenteral administration or oral administration.
Special instructions for using the gel
What you need to know in order to achieve the maximum effect of treatment with the drug "Dalacin" (for acne). Reviews about this tool contain a lot of precautions. Let's consider them in more detail.
During the application of the gel, it is necessary to avoid getting the medication on the mucous membrane of the mouth and the lining of the eyes.
After using the drug, it is recommended to wash your hands thoroughly. If the gel accidentally gets on sensitive surfaces (abrasions on the skin, eyes, mucous membranes), then they should be washed immediately with cool water.
The use of the drug parenterally or orally can lead to the development of pseudomembranous colitis and severe diarrhea. As for outdoor use, such cases are very rare. However, particular care must be taken. Thus, with the development of prolonged or severe diarrhea, the medication should be immediately canceled, and if necessary, appropriate medical measures should be taken.
As a rule, undesirable effects after using the gel appear within a few weeks after completion of therapy. Prescribing drugs that reduce gastrointestinal motility can prolong, as well as worsen, the course of the deviation.
The drug "Dalacin" (gel): reviews before and after use
Now you know what the medicine in question is intended for and how to use it correctly.
In order to have a clearer understanding of how this tool works and how effective it is, we decided to consider a few patient reviews.
Some of the fair sex, trying to get rid of acne, noted the fact that before using the gel, acne was small, and after that it became large and open. Experts explain that such a reaction is allergic. Therefore, before using the drug, you should definitely do a test.
There are consumer reviews and that this medication does not affect skin rashes. In other words, the gel does not cure, but does not worsen the patient’s position. In this case, doctors recommend contacting a specialist and identifying the true cause of a disease such as acne.
It is impossible not to say that there are quite a large number of patients who have been treated with Dalacin rather quickly to get rid of acne and acne.
Price and analogues
Due to the high cost, acne gel Dalacin is often replaced with cheaper analogues. Indeed, not every patient is ready to give more than 700 Russian rubles for a drug in 30 g. In this case, you can purchase such products as Zerkalin, Klindes, Dalacin Ts Phosphate, Clindamycin, Klimitsin, Klindatop, Klindatsin, Klindafer, Klindovit, etc.