Gliatilin is a representative of nootropic drugs. Its main property is the improvement of a personās cognitive abilities (attention, memory, productivity and ability to think), as well as the normalization of impaired circulation of the brain.
The medicine is used for cerebrovascular stroke, memory loss, circulatory failure in the brain (discirculatory encephalopathy) and dementia (acquired - senile, Alzheimer's).
In this article, we will consider what kind of drug is Gliatilin, instructions for use and customer reviews.
Composition and release forms
Now the release of "Gliatilin" is arranged in two dosage forms:
- capsules for oral administration;
- for introduction into muscle tissue or veins - a solution in ampoules.
The drug in capsules is available in packs of fourteen pieces, the injection solution is in ampoules of four milliliters, packed in cardboard boxes, one or three ampoules in each.
The injection form of the drug is made in the form of a clear, odorless, colorless liquid. Oval-shaped capsules are clad in a yellow gelatin shell. Inside they are filled with a viscous, colorless solution.
As stated in the instructions for use of "Gliatilin", in tablets and solution for injection, the active substance is alfoscerate. Capsules, they are also tablets, contain its dosage in the amount of 400 mg per pill, and the solution is 250 mg per milliliter.
Excipients in the injection solution are only distilled deionized sterile water, and in capsules are ezitol, sodium ethyl parahydroxybenzoate, purified water, sorbitan, sodium propyl parahydroxybenzoate, iron (III) metahydroxide, gelatin, titanium dioxide, glycerin.
Drug action
The instructions for use of "Gliatilin" say that the drug is a central cholinomimetic, in other words, activates the cholinergic receptors of the brain.
According to pharmacological properties, the drug is a neuroprotector and nootropic.
Upon reaching the brain, the components of "Gliatilin" disintegrate, releasing:
- Choline is a substance involved in the synthesis of acetylcholine, which is the main conductor of nerve excitation. Only thanks to this substance is the impulse from one brain cell transmitted to another. In fact, the presence of a sufficient volume of acetylcholine determines the speed of information exchange in the structures of the brain.
- Glycerophosphate is a substance involved in the synthesis of phospholipids that form the cell membrane. Naturally, with their sufficient volume, the cells create a strong membrane that reliably protects them from the negative effects of environmental conditions.
Features of the drug
Instructions for use and indications for "Gliatilin" indicate that the medicine:
- improves and increases the transmission speed of nerve cell signals between brain structures;
- helps neurons gain strength and resistance to negative environmental factors, such as hypoxia and others;
- improves blood circulation in the vessels of the brain;
- accelerates the metabolism in brain cells;
- regains consciousness after damage as a result of injuries of various brain structures;
- increases bioelectric activity and blood flow in the affected areas;
- contributes to the most rapid disappearance of the symptoms of neurological disorders and the restoration of stable consciousness;
- quickly restores structures damaged as a result of ischemic stroke of cerebral vessels;
- increases cognitive abilities (memory, thinking and attention) in those who suffer from mild or severe dementia, which is caused by impaired cerebral circulation of various genesis (for example, discirculatory encephalopathy, vascular atherosclerosis, Alzheimer's disease, arterial hypertension and others).
In all people without exception (suffering from impaired mental activity and healthy), "Gliatilin" improves emotional stability and mood, activates thought processes, relieves apathy and irritability.
Indications for use
According to the instructions for use, indications for "Gliatilin" are justified by the following conditions and diseases:
- the period after a traumatic brain injury, in which the brain stem is mainly affected and the corresponding symptoms are present (coma, impaired consciousness and others);
- recovery period after ischemic stroke;
- chronic circulatory failure in the cells and vessels of the brain (discirculatory encephalopathy);
- recovery period after hemorrhagic stroke;
- degenerative syndromes, which are manifested in impaired memory, disorientation, confusion, decreased concentration and motivation, decreased initiative;
- imbalance of emotional stability and behavioral disorders, for example, emotional lability, decreased interest in life, irritability, senile pseudomelancholy;
- caused by various causes of dementia (senile, Alzheimer's, mixed);
- Alzheimer's disease, Huntington's chorea;
- various disorders of cognitive function (confusion, impaired mental processes, disorientation, decreased memory and decreased attention, motivation).
"Gliatilin": instructions for use
Define the general provisions for taking the drug, indicated by the instructions.
The medicine in capsules is taken orally as a therapeutic agent for chronic conditions for a long time.
The injection solution is administered intramuscularly or intravenously and is used to treat acute conditions for a relatively short period of time.
In addition, serious diseases require a combination of the use of the drug in both forms. This happens in such a way that the introduction of the solution is prescribed first, and then the treatment is continued by oral administration of the capsules.
The choice of treatment with Gliatilin is carried out by the attending physician and depends on the severity of the disease and the condition of the patient.
Next, consider the dosage regimen described in the instructions for use of "Gliatilin", analogues, composition and dosage of the drug.
Rules for taking pills
Capsules are swallowed whole, without opening and not biting, before eating. Drink plenty of water without gas.
If it is necessary to take capsules several times during the day, the daily dosage is divided into unequal parts so that most of the dose falls in the morning, and the smaller part for the day or evening. This is due to the fact that it is necessary to minimize the stimulating effect of the drug, which can cause insomnia.
Treatment of chronic diseases is carried out in capsules - one (400 mg) two to three times a day for three to six months.
Acute conditions require first an injection course of one (1000 mg) ampoule per day for one to two months, and then they switch to taking capsules orally - two in the morning and one day for six months.
If there is a need, treatment is carried out with repeated courses, having sustained a break between them for at least four to six months. It must be remembered: the longer the previous course of therapy was, the longer should be a break until the next.
As stated in the instructions for use of "Gliatilin", if taking the capsules causes nausea, then treatment is continued, reducing the dose of the drug.
Injections
The drug solution is intended for intravenous or intramuscular administration.
The drug is administered intravenously through a dropper. Previously, the contents of the ampoule must be diluted in fifty milliliters of saline. Ready infusion solution is slowly administered at a rate of 60-80 drops per minute.
For intramuscular injections, the solution is administered with a sterile syringe of the required volume. For example, if you want to enter 1000 mg of the drug, then you need a syringe with a volume of 4-5 ml. If you need to enter half of this dose, you will need a 2 ml syringe.
Instructions for use of "Gliatilin" and analogues say that it is recommended to put injections into the muscle tissue in the upper outer part of the shoulder, the anterolateral surface of the thigh, and thin people in the front wall of the abdomen. Experts do not recommend injecting āGliatilinā into the gluteus maximus muscle, since its deep lying on this part of the body increases the risk of introducing the solution into the fat layer under the skin, from where the drug does not enter the bloodstream at a sufficient speed.
Injection Rules
The ampoule with the injection should be opened immediately before use, and the remaining unused part should be discarded. Store the solution in an open container is prohibited.
The dosage of the drug for injection of both types in different conditions or diseases is the same. It is equal to 1000 mg, that is, one full ampoule of a solution of 4 ml at a time. Intramuscular injections are given once a day, and intravenous injections are given one to three times, depending on the doctor's prescription. The duration of the injection treatment for any disease is the same, it is seven to ten days.
Injections are recommended before meals in the morning. The method of administration of the drug is determined by the doctor depending on the condition of the patient. If the patient is in critical condition, has lost consciousness, or cannot move independently, then Gliatilin is administered intravenously. With the ability of a person to move and adequately respond to surrounding reality, the drug is prescribed intramuscularly.
"Gliatilin" for children
Injections and capsules of "Gliatilin" (400 mg each) are prescribed for children in order to eliminate mental, motor or speech development delays, as well as to minimize the effects of birth injuries and previous perinatal encephalopathy.
Less commonly, the drug is used to treat concussions and bruises of the brain or traumatic brain injuries.
Children under the age of seven are usually prescribed Gliatilin injections, since when using the solution it is possible to measure the right dose of medication.
If capsules are used for treatment, the child, regardless of age, will have to give an adult dose - it is impossible to divide the contents into several parts.
According to the instructions for use of "Gliatilin" for children, injections are also preferable because the course of treatment with them is much shorter (from five to fourteen days) than tablets (from one to three months). In addition, injections are more effective than capsules.
If you have to give the drug in capsules to a child who cannot swallow the pill whole, then the contents of the capsule are pulled with a syringe, poured into the baby's mouth and allowed to drink water without gas.
Contraindications and side effects
Usually, taking "Gliatilin" is well tolerated, rarely side effects occur in the form of nausea, allergic reactions. If nausea occurs, the dose of the drug is reduced and treatment continues until the end of the course. With allergic manifestations, the drug is stopped.
With an overdose of the drug, nausea, vomiting, dyspepsia occurs, which is manifested by flatulence, bloating, belching, heaviness in the stomach, diarrhea or constipation. In this case, you should rinse your stomach, take an adsorbent and take a break in taking the drug for a day. Further treatment can be continued according to the usual scheme.
Pregnant and breastfeeding taking "Gliatilin" is not recommended, as there is insufficient data on the effect of the drug on the fetus.
Analogs
In the pharmaceutical market, most drugs have analogues. āGliatilinā is no exception - a description of the instruction, prices and reviews are given in the article.
Similar drugs are divided into two groups:
- Synonyms are drugs with the same active substance as the prototype (choline alfoscerate).
- Analogs - contain active substances that are different from the prototype, but are similar in therapeutic effect.
The first group includes:
- "Gleazer";
- "Delecitis";
- "Noocholin Rompharm";
- "Choline alfoscerate";
- "Cholitilin";
- "Cereton";
- Cerepro.
The second group includes:
- Ginkoum, Vinpocetine Forte, Vinpotropil;
- Cavinton, Corsavin, Amilonosar;
- āAcefenā, āGinkgo Bilobaā, āBravintonā;
- "Glycine", "Carnitex", "Idebenone";
- "Gopantam", "Memotropil", "Demanol";
- "Minisem", "Calcium hopantenate", "Combitropil";
- Neupilept, Kogitum, Neuromet;
- "Lucetam", "Pantogam", "Cortexin";
- "Cellex", "Celestab", "Phenotropil";
- āFezamā, āTiocetamā, āTelektolā, āSemaxā;
- "Piracetam", "Piracezin", "Pineamine";
- "Pikogam", "Pikanoyl", "Picamilon", "Pantocalcin";
- Pantogam, Omaron, Nootropil, Noopept;
- "Nooklerin", "NooKam", "Noben", "Pyriditol";
- "Escotropil", "Epithalamin", "Encephabol";
- Cerebrolysin, Cerebrolysate, Ceraxon.
Previously described instructions for the use of "Gliatilin." The price and reviews of the drug will be presented below.
Drug price
The cost of the drug "Gliatilin" in pharmacies in various cities of Russia varies in the following ranges:
- Gliatilin injection solution, three 4 ml ampoules, 1000 mg - from 556 to 676 rubles;
- capsules "Gliatilin", 14 pieces of 400 mg - from 720 to 823 rubles.
Before use, it is necessary to consult a specialist.
Reviews
Most reviews of "Gliatilin" are positive, since the drug has a good therapeutic effect.
Testimonials of patients indicate that the drug returned high activity and vigor, improved working capacity, productivity of thinking, attention and memory.
Those who suffered a stroke note that after taking the drug, thinking was restored, memory and attention improved.
As for children, the reviews say that it is important to follow the rules for the use of Gliatilin for children. When this condition is met, after the course of treatment, the children begin to speak better, and motor and physical development accelerated in the kids.
There are also negative reviews about the drug, they are mainly associated with the occurrence of side effects from poor tolerance of the drug.