In the article, we will consider the shelf life of Glycine and the instructions for it.
This is an agent that affects brain metabolism, an amino acid. The basic substance is a central inhibitory neurotransmitter that improves metabolic processes in the brain tissue and has an antidepressant and sedative effect.
What is the shelf life of Glycine? This is a common question.
Shelf life of the drug
The shelf life of this medication is 3 years. After the expiration of this time, the medicine is prohibited to use.
How to store the drug?
Storage conditions "Glycine" are indicated in the instructions.
Manufacturer's recommendations are as follows. Store the medicine at a temperature not exceeding 25 ºC in a dry place, protected from sunlight.
The shelf life of “Glycine” directly depends on compliance with storage conditions.
Composition and form of release
The pharmacological agent “Glycine” is produced in the form of tablets, which contain an interchangeable amino acid, which is directly involved in the metabolism of various structures of the central nervous system. The medicine is used in the treatment of certain pathologies of the brain.
Glycine tablets are white in color and have a round, cylindrical shape. One tablet as an active element contains 100 mg of glycine (amino acids). In addition, some additional components are included, among which 1 mg water-soluble methyl cellulose and magnesium stearate in the same dosage.
Tablets are packaged in blister packs of 50 pieces. A cardboard bundle contains one blister strip packaging and instructions for the use of a medical product.
In addition to tablets, there is also a powder form of this drug. The powder is packaged in disposable bags. Liquid "Glycine" does not exist.
Also on sale you can find the drug "Glycine Forte." It is no less popular among patients.
What is the difference between “Glycine” and “Glycine Forte”, we will describe below.
Pharmacological properties
The amino acid glycine, which is the main active substance of the drug, has a significant effect on the metabolism of neurocytes, which are cells of the nervous system in the brain, and inhibitory protective effect on the structures of the central nervous system.
So, what does the “Glycine” medicine help from?
This drug has several pharmacological effects, which include:
- Mood improvement.
- Reducing the severity of psycho-emotional stress, irritability, a tendency to aggression.
- Improving sleep, its duration and stabilizing the correct physiological phase sequence, facilitating the process of falling asleep.
- Improving mental performance.
- Reducing the intensity of manifestations and severity of disorders of the functionality of the brain after ischemic disorders (lack of blood supply) or hemorrhagic stroke (blood from a bursting vessel entering the brain).
- Reduction of autonomic disorders associated with impaired functional activity of the subcortical structures and cerebral cortex, including menopausal disorders.
- Reducing the severity of the negative effects of toxins taken by drugs and alcohol, which have the ability to inhibit the activity of the structures of the nervous system.
After sublingual resorption (resorption under the tongue) of this medicinal product, its active substance is absorbed into the general bloodstream. It is able to penetrate the blood-brain barrier and accumulate in the structures of the central nervous system, where it has a direct therapeutic effect. Glycine undergoes a metabolic process in the cells in a natural way to the final decay products - water and carbon dioxide, which are excreted from the body by the kidneys and lungs.
Consider below the indications for the use of "Glycine" for children and adults.
In what cases is the drug prescribed?
A medication is prescribed for a number of pathological conditions, accompanied by a violation of the functional activity of the central nervous system. These diseases and disorders include:
- decreased intellectual performance as a result of chronic or periodic overwork;
- stressful situations in which the level of psychoemotional stress is significantly increased (conflict situations, exam period);
- deviant varieties of behaviors in adolescents and children, which are characterized by a deviation from generally accepted norms of interpersonal and social relations;
- emotional lability (sudden changes in mood), excessive emotional excitability, decreased mental disability as a result of functional and organic pathologies of the central nervous system;
- encephalopathy (brain pathology), resulting from past traumatic brain injuries, prolonged intoxication with substances that have a depressing effect on the central nervous system (some drugs, narcotic compounds, alcoholic beverages);
- neurosis-like states and neuroses;
- negative complications of an ischemic or hemorrhagic stroke;
- vegetovascular dystonia of various nature of origin, including such vegetative disorders that accompany the menopause.
In addition, the prophylactic use of this drug is possible until the development of pathological symptoms in cases of increased functional load on the departments of the central nervous system.
Contraindications
The medicine "Glycine" is absolutely safe. The only strict contraindication to the appointment of tablets is the individual intolerance of this amino acid and hypersensitivity to it or additional elements of the drug.
Manufacturer "Glycine"
An important role in the treatment of the patient is played by the manufacturer of this drug. Over time, various pharmaceutical companies began to produce it. The direct analogue may be an improved medicine or not have a significant difference. To date, there are such major manufacturers of "Glycine":
- "Biotics";
- "VIS";
- "Ozone";
- "Evalar";
- Thorne Research;
- Country Life.
Instructions for use
Glycine tablets are intended for sublingual administration. To do this, the necessary dose of the drug must be placed under the tongue and kept there until completely dissolved. A similar use of a medicine does not depend on a meal time. In addition, there is no need to drink the medicine with water.
According to the instructions for using the dose of “Glycine” for adults and children, as well as the duration of therapy depend on many factors:
- With a functional decrease in intellectual performance due to excessive fatigue, as well as with emotional stress and memory loss, in children after 3 years of age with a deviant form of behavior and a delay in mental and mental development, the drug is prescribed 1 tablet 2-3 times a day for 14-30 days .
- With functional and organic types of brain damage, which are accompanied by sleep disorders, increased psychoemotional excitability and instability of mental processes - for patients under the age of 3 years, ½ tablets 2-3 times a day for 1-2 weeks. Children over 3 years old and adults are prescribed 1 tablet with the same frequency of doses per day, the duration of the therapeutic course up to 2 weeks. According to clinical indications, the course of therapy can be extended up to 1 month.
- In case of a stroke of the brain (including an ischemic one) - 10 tablets within 3-6 hours after the stroke, then 10 tablets per day for a course of 5 days. In the future, therapy involves taking this drug 1 tablet 3 times a day for 30 days.
- If the process of falling asleep is disturbed, 1 tablet is prescribed half an hour before bedtime.
- With the complex treatment of alcohol or drug dependence, as well as toxic form encephalopathy, the treatment regimen involves taking the medicine 1 tablet 2-3 times a day for 1 month. A similar therapeutic course can be repeated up to 6 times during the year.
- With the complex therapy of post-infectious (after a neuroinfectious disease) brain dysfunction, the dosage and course of treatment are set individually.
How "Glycine" works, it is important to find out in advance.
Side effects
Glycine tablets are generally well tolerated by patients. Sometimes it is possible to develop an allergic reaction in the form of a skin rash, itching, urticaria. There is no evidence of a severe allergic reaction in the form of angioedema or anaphylactic shock.
Special recommendations
Before you start taking this medication, it is recommended that you carefully study its instructions. It is necessary to pay attention to the fact that the medicine "Glycine" is able to reduce the therapeutic effectiveness of antipsychotics, sleeping pills and anticonvulsant pharmacological agents. Information on the effect of the drug on the speed of mental and motor reactions is not provided.
What is the difference between Glycine and Glycine Forte?
Pharmaceutical company "Evalar" produces a medicine called "Glycine Forte." This tool has similar indications for use, a range of therapeutic effects, the same active active element. However, it differs from the usual drug "Glycine" somewhat expanded composition. So, in addition to the main substance of glycine and additional components, the medicine “Glycine Forte” also contains vitamins (B 1 , B 12 , B 6 ). Dosages are maintained within the same limits.
Glycine Forte is enriched with vitamins, which plays an important role in the treatment of diseases associated with impaired functional activity of the human brain. They enhance metabolic processes, which allows you to quickly deliver beneficial substances to the brain through the bloodstream, increase attention and memory. More often than the usual "Glycine", "Glycine Forte" is prescribed in childhood, since vitamin deficiency of B vitamins is observed more often in children than in adult patients.
Reviews
This medication has long been used in domestic clinical practice, and there are quite a lot of reviews about it, and most of them are positive. Patients note the high effectiveness of this medication, a mild sedative effect after taking it. Many parents give this medicine to their children, especially when they are in school. At the same time, they note that in children memory, perseverance improves significantly, they become more calm, sleep is normalized. This is especially noticeable, according to the parents, in the adaptation period of training.
Many adults also observed the above effects from Glycine powder and tablets. There is practically no information about adverse reactions, except in the few cases when, after taking this medication, patients with a tendency to allergies had a skin rash and slight reddening of the skin. Such reactions quickly disappeared and did not cause people significant concern.
Patients say that when taking the “Glycine” medication, their excessive emotionality decreased, irritability, negative manifestations of depressive states and various psychoses disappeared. It is also known that many people take this pharmacological drug in stressful situations, which positively affects their general physical and psychological condition. Glycine is often taken by young people before exams in order to reduce emotional stress, focus more quickly and concentrate.
The doctors' comments about this medication are also mostly positive. Experts note that such a medication can be taken without age restrictions, since it is a natural amino acid and does not harm the body. However, it is extremely important to observe the dosages of this medicine, since exceeding them can negatively affect health and well-being.
We examined the shelf life of Glycine and the instructions for it.