Currently, due to the increase in the level of stressful factors, many are wondering how to use the medication to reduce anxiety, strengthen sleep disturbance and stabilize one's condition.
Among over-the-counter pharmacy products, there are often drugs that are recommended as antidepressants, but they are mainly homeopathic medicines that do not provide complete assistance in some cases.
Depression Pictures
Before you get involved in MAO inhibitors, the drugs should be thoroughly studied or consult a doctor. Drugs of the antidepressant group can affect many body functions: the above-mentioned MAO inhibitors (monoamine oxidases) have a wide range of side effects, which will be discussed later. But even earlier, one should realize whether the body requires such an intervention, or is it just a whim caused by the desire to alleviate certain moments of his life. Most people on Earth have experienced depressive conditions, and their presence is due to their need for stress.
A lot of authoritative works of our contemporaries and predecessors have been written about the benefits of moderate stress. In most cases, the negative perception of stress is caused by the advertising of antidepressants, which offers consumers to get rid of it as an unnecessary thing that spoils our lives, as well as “toxins”, so to speak ...
Stress Drives Progress
However, stressful conditions serve as a kind of motor that helps a person survive and feel the “black bars” of his life so that he can see “white” ones. If there were no darkness, we would not know what light is (F. Aquinas). If there were no stress, no one would feel calm. But, besides the Theosophical, stress has a completely scientifically based physiological background. Stress enhances immunity, stimulates the regenerative abilities of the body, improves memory and increases stamina. These facts are scientifically confirmed. Therefore, before using sedatives, antidepressants, drugs - MAO inhibitors, it should be determined how necessary they are in a given situation.
Herbal preparations (antidepressants and MAOI)
St. John's wort is a favorite among over-the-counter and weak MAOI drugs. This plant has been studied for centuries, unlike new drugs, more studied. It is the main component of such popular drugs as Negrustin, Deprim.
A cheaper analogue is the alcohol
tincture of St. John's wort, which is the least convenient in everyday use, but excludes the presence of additives, which in some cases may manifest the effects of individual intolerance.
Valerian. It is also the basis for the preparation of many dosage forms. Does not belong to the group of "MAO inhibitors". The list of drugs from the group of selective and non-selective monoamine oxidase inhibitors, contrary to popular belief, does not provide for valerian as an adjuvant because of incompatibility. Like St. John's wort, valerian is a drug with a balanced natural biochemical composition and is dispensed in pharmacies without a prescription.
Motherwort. Certain types of this plant are used not only in neurology, but also in general therapy and cardiology. Motherwort tinctures have a calming and tonic effect with regular use. Medicinal preparations based on motherwort serve as the basis for herbal teas, and its extract in combination with eucalyptus is an effective means for inhalation.
Synthetic drugs
Drugs of a non-plant origin have a shorter history, and the experience of treatment with “pioneers from the 50s” was very doubtful. However, due to the spasmodic development of the pharmaceutical industry, the drug market currently offers a fairly wide range of drugs that are more pronounced in comparison with plant-based drugs.
MAO inhibitors became a big leap in the treatment of mental disorders and borderline depressive states. The list of drugs in this group has 145 trade names.
How IMAO work
The principle of action of drugs of this group is based on slowing down the destruction of one or more groups of monoamines and increasing the concentration of certain mediators between the two synapses. Such mediators include norepinephrine, serotonin, dopamine and others. In the future, by increasing the concentration of a certain mediator, the desired therapeutic effect is achieved. The question of what applies to selective MAO inhibitors, and what to non-selective, is decided by a simple wording. If the drug stimulates an increase in the concentration of one mediator, then it is considered selective. If several - then indiscriminate accordingly.
What are MAO inhibitors: a list of requirements and precautions for the use of drugs in this group because of the possibility of side effects
1. Mandatory medical intervention. Preparations of this group, with the exception of herbal medicines, for the most part belong to the group of drugs dispensed only by prescription. And not in vain (see the next paragraph).
2. The exact dosage. The intake of drugs of this group should be carried out regularly and in certain doses, taking into account the physiological characteristics of the body. You can not take these drugs, based on the principle of "more nervous - I drink more pills." The effect of an overdose may be diametrically opposed to the expected. Recently, unconscious poisoning with MAO inhibitors has often been observed.
Drugs are taken in large doses in a domestic environment in order to "calm down." And, sadly, there are cases when people calm down forever.
3. Differentiation with a kind of human activity. In all instructions for the preparations of this group, the column “with caution” is indicated and the group of persons is called for which the administration of drugs in connection with the performance of a certain work is incompatible or incompatible. Antidepressants of this group can affect the speed of the reaction, which can disastrously affect the work of drivers, pilots, and employees of law enforcement agencies. The presence in the blood and urine of residual enzymes of drugs of this group can show positive results in athletes (like doping).
4. The principle of calculating the side effect common to the IMAO group. Drugs in this group can cause mental and somatic disorders. From the psyche - lethargy, feeling tired, withdrawal syndrome. In complex cases - mental disorders: exacerbation of schizophrenia, suicidal tendencies. From the somatic side: blood pressure disturbance, negative effect on parenchymal organs (liver, kidneys).
MAO inhibitors. List of drugs often used in the practice of neurologists and psychiatrists
Table-list of drugs with notes| A drug | View | Indications | Note |
| Aurorix | IMAO reversible action | Depression of various etiologies, sociophobia | Undemanding to diet. Trade name of the active substance macrobenide |
| Pyrazidol | Electoral IMAO | Depression of various origins, withdrawal symptoms, b. Alzheimer's | Domestic drug at a reasonable price |
| Behol | Selective IMAO reversible action | Shallow Depression, Hypochondria | Domestic drug |
| Incazan | Selective IMAO reversible action | Depression of various origins. Schizophrenia, manic-depressive psychoses | Also known as metralindole. |
| Selegelin | Electoral IMAO | Parkinson's disease, polyetiological parkinson syndromes (excl. Drug) | Synergism with Levodopa |
These drugs are the most commonly used in practice due to their high efficiency and predictable prognosis of the therapeutic effect. These are the most profitable drugs in the price / effectiveness ratio among the group of "MAO inhibitors". The list of drugs with a similar and similar action and other commercial names is more extensive, because 43 pharmaceutical manufacturers are supplied to the domestic market, and many drugs are generics.
conclusions
However, a third element should be included in the price / quality duo, which many consider to be the “third superfluous”. This is individuality. Only a doctor can fully determine which drug of antidepressants is suitable for a particular person. And to decide what place depression takes in a person’s life, whether he will be happy or not, only he can.
The data given are not recommendations for self-medication and are published for informational purposes only.