In the instructions for use, Baklosan tablets are designated as a central muscle relaxant. They reduce the excitability of the terminal sections of sensitive afferent fibers and suppress intermediate neurons, thereby inhibiting the poly- and monosynaptic transmission of nerve impulses. In addition, the tool removes the preliminary tension of the muscle spindles.
The main component of the composition of "Baklosan" - baclofen. The drug has a high absorption rate. Its maximum concentration in the blood is achieved 2-3 hours after taking the pill. The drug is rapidly absorbed by the digestive system. It is excreted from the body by the kidneys. The medicine reduces cramps, lowers the tone of skeletal muscles, as a result of which the sensitivity of the limbs also decreases.
Description and storage
Pills "Baklosan" have a round biconvex shape, white. They are released in two dosages: 10 mg (there is a dividing risk), 25 mg. They are Packed in polypropylene jars of 50 pieces, which are packed in a cardboard box. Release the drug without a doctor’s prescription.
Shelf life of the drug is 5 years. It should be stored in a dry and dark place at a temperature not lower than +25 ° C, away from children.
Indications
Tablets "Baklosan" indications for use are as follows:
- cerebral paralysis;
- multiple sclerosis;
- head injuries;
- diseases of the spinal cord of traumatic, degenerative and infectious origin;
- alcoholism;
- stroke;
- disorders of the nervous system;
- meningitis.
Often, experts prescribe a medication for various injuries, fractures, dislocations and pathologies of the spinal cord. Alcohol and Baklosan (indicated in the instructions for use) are incompatible.
The drug should be taken with meals. The tablet is washed down with water. Treatment begins with 5 mg three times a day, the dose is increased every three days. The amount of the drug is increased until a significant improvement is observed in the patient. The dosage is increased only by the doctor, in some exceptional cases it can reach 25 mg. Cancellation of "Baklosan" should be agreed with the attending doctor. The maximum daily dose is 100 mg.
Side effects
Side effects of "Baklosan" rarely recorded. With great care, the medication should be taken by older people who are susceptible to the components of the drug. Possible side effects:
- nausea and vomiting;
- constipation and diarrhea;
- weakness and dizziness;
- swelling;
- urinary incontinence;
- depressive state;
- drowsiness;
- numbness;
- dry mouth.
The drug is produced in the form of small biconvex tablets. The main component of the medication is, as already mentioned, baclofen. Instructions for use with Baklosan indicate that the additional components are potato starch, talc, magnesium stearate, gelatin and lactose.
Overdose
An overdose of the drug manifests itself in the following symptoms:
- severe muscle hypotension;
- respiratory depression;
- confusion of consciousness;
- coma (in cases when consciousness returns, muscle hypotension can be observed up to 72 hours).
According to the instructions for use with "Baklosan", in case of poisoning with the drug and the appearance of the above signs, diuretics should be given immediately to the patient, heavy drinking is recommended. If respiratory depression is observed, then the procedure for artificial ventilation of the lungs is prescribed.
special instructions
If Baklosan is prescribed for a patient with diabetes mellitus or liver diseases, then periodically it is necessary to control the activity of special enzymes - hepatic transaminases, as well as blood glucose and alkaline phosphatase.
According to the instructions for the drug, everyone who takes it, at the time of treatment should refuse to perform hazardous activities that require a quick mental and motor reaction, increased attention.
Key aspects of addiction
The medicine is not addictive in the physical design. Chemically, the drug is not dangerous, but baclofen as a functioning substance can activate the psychological need for continuous use of tablets.
It is known that "Baklosan" is able to constantly increase the euphoric result from other drugs, for this reason addicts with experience use this medication to enhance the effect of narcotic substances. In some cases, they try to combine muscle relaxant with alcohol, which is deadly.
Tolperizon
The main active substance is tolperisone hydrochloride. Auxiliary components - citric acid, lactose acid (granulated sugar), hyprolose, crospovidone, stearic carbon dioxide.
pharmachologic effect
"Tolperizon" - an analogue of "Baklosan", belongs to the group of N-anticholinergics. A muscle relaxant drug that has a selective effect (depressing) on the caudal region of the reticular formation of the brain has central anticholinergic properties. On the peripheral parts of the human nervous system does not have any effect. The drug is characterized by a weak vasodilating and antispasmodic effect.
Indications for use
The drug is prescribed in the following cases:
- Diseases with rigidity, spasm and dystonia of the muscles, obliterating arterial ailments (thromboangiitis obliterans and atherosclerosis of the vessels of the upper and lower extremities, diabetic angiopathy, Raynaud's syndrome).
- Cerebral palsy and spinal cord (limb contracture, muscle spasm and hypertonicity, spinal automatism).
- Movement disorders resulting from damage to the subcortical-thalamic connections and basal ganglia.
- Little's disease, disorders of post-thrombotic venous and lymphatic circulation, trophic ulcers of the lower leg, epilepsy, hypertonicity, combined with impaired muscle tone of a different kind, as well as encephalopathy with vascular etiology.
Dosage, contraindications and overdose
The drug is taken orally (regardless of food intake), washed down with water. The initial dosage for adults is 50 mg two or three times a day. Gradually increase it, bringing to 150 mg. The duration of the course is determined by the doctor, it depends on the nature of the course of the disease and its severity.
The drug can not be taken in the following cases: myasthenia gravis, age up to 1 year, hypersensitivity, as well as the period of pregnancy and lactation.
An overdose of a non-biological element (tolperisone) can provoke nervousness (especially in a child), respiratory paralysis, convulsions (tonic and cyclic), ataxia.
Tizalud
Indications for the use of "Tizaluda" analogue "Baklosan":
- painful muscle contractions caused by damage to the spine, as well as surgical intervention (postoperative period);
- skeletal muscle spasm in neurological diseases: multiple sclerosis, myelopathy, degenerative diseases of the spinal cord, stroke).
Contraindication: sensitivity to the active substance - tizanidine. With caution, the drug is prescribed for impaired renal and hepatic function. Tizalud should not be used during pregnancy, except in situations where the predicted benefit for the mother is greater than the likely threat to the fetus. If it is necessary to use the substance during lactation, it is necessary to stop breastfeeding.
Midokalm
"Midokalm" is a central muscle relaxant. Instructions for use with Baklosan and Midokalm are very similar. The latter is prescribed in the following conditions:
- muscle hypertonicity;
- accompanied by muscle dystonia (including childhood) encephalopathy;
- muscle spasm;
- Cerebral palsy;
- neurological organic and degenerative diseases, in which there is a tone of striated muscles.
The main effect that Midokalm exerts is muscle relaxation and the solution to the problem of muscle spasms caused by various factors. The effectiveness of the drug is clinically proven in blind studies. The action of "Midokalm" is central, due to which the effect is carried out directly on the brain,
The drug has contraindications:
- individual intolerance;
- epilepsy;
- psychoses
- Parkinson's disease.
Acceptance of the drug during pregnancy is allowed in exceptional cases, when the effectiveness of therapy is higher than the risk to the child.
"Midokalm" is taken orally, you should swallow a tablet with water. At the beginning of the dose, the dose for an adult is 50 mg two or three times a day, followed by a three-fold increase in dose. In case of side effects (muscle weakness, low blood pressure, headache), the dose should be reduced.
Other properties
Other useful properties of the drug: a decrease in the high excitability of the spinal cord, stabilization of the membranes of susceptible and motor fibers, a decrease in rigidity and muscle tone. Unlike other similar pharmaceuticals, Midokalm does not show a sedative effect, does not exert an excessively negative effect on the hematopoietic system.
Other analogues
In the pharmacy you can find a large number of analogues, such as:
- Catadolone
- Memikar;
- Memorel;
- "Memin".
With great care, you should take Katadolon. This drug is strong enough, but it is not considered narcotic. It has a strong analgesic effect. "Baclofen" also helps to get rid of pain, relieve tension in the muscles. With the help of Memorel tablets, you can restore your normal mental state, improve your memory. Memantine is available in powder form and helps increase stamina.