The drug "Octreotide", the price of which is more than 3000 r., Helps to suppress pathologically increased production of growth hormone, serotonin and peptides in the gastroenteropancreatic system. The tool has a lasting effect.
Indications
The drug "Octreotide" is prescribed for acromegaly (in the case of ineffective surgery, treatment with dopamine agonists, radiation therapy, inoperable patients or those who refused surgery), carcinoid and other tumors of the gastroenteropancreatic system, accompanied by carcinoid syndrome. Indications include inflammation in the heart valves, excessive local expansion in the capillaries, skin pigmentation, chronic enteritis, telangiectasia, inflammation in the small intestine. A medication is prescribed for refractory diarrhea in AIDS patients. Recommended tool "Octreotide" (instructions for use confirms this) for the prevention of complications after interventions on the pancreas. The indications include tumors accompanied by hypersecretion of somatoliberin, a vasoactive intestinal peptide, gastrinoma, glucanoma.
Dosage regimen
Means "Oktreotid" the application instruction recommends to enter subcutaneously. Dosage - 0.05-0.1 mg. The interval between injections is eight to twelve hours. The subsequent appointment is carried out taking into account the indicators of monthly control over the content of growth hormone in the blood, as well as after analysis of tolerance and clinical manifestations. The optimal dose per day for most patients is 0.2-0.3 mg. The maximum amount per day is 1.5 mg. To prevent complications, the drug is administered an hour before laparotomy. After the intervention, injections are carried out three times a day at a dose of 0.1 mg. The course lasts seven days. In old age, dosage adjustment is necessary.
Medication "Octreotide." Instructions for use. Adverse reactions
The drug can provoke anorexia, spastic pain (due to sharp contractions of smooth muscles in the internal organs) in the abdomen, vomiting, nausea, steatorrhea, diarrhea. Despite the increase in excretion with feces of fat, in practice there is no indication that prolonged use of the medication can cause absorption disorder. Some patients have symptoms similar to acute intestinal obstruction. To reduce the negative reactions from the gastrointestinal tract, it is recommended to administer the drug between meals or at night. Patients with tumors in the pituitary gland should be carefully monitored due to the likelihood of their increase with impaired visual function. Due to the treatment of neoplasms in the organs of the gastroenteropancreatic system, in some cases, a relapse of symptoms may occur. Against the background of prolonged use of the drug "Octreotide" (instructions for use contain such data), the formation of calculi in the gallbladder is likely. It is also possible impaired glucose tolerance when eating, the development of hyperglycemia (persistent type).