Almost every person is sure that nothing can happen to him. Take a look back at your life. After all, it is filled with stress, overexcitation, excitement, violent emotions ... Of course, this is a natural process, so no one even argues with that. But if you do not know how to control your overexcitation, in which pressure rises, then it is impossible to say that you are not threatened with a stroke or rupture of an aneurysm.
Such pathological changes occur directly in the brain and are associated with hemorrhages. Aneurysm is a protrusion or rupture of the vessels of the brain. Stroke is a more serious consequence of diseases of the circulatory system associated with hypo- and hyperpressure.
Medical statistics suggest that one third of the most dangerous diagnoses are precisely brain ailments. They can develop due to circulatory failure, overexcitation, excitement and intracranial injuries. A person can receive the latter as a result of a fall from a height, during a car accident, as well as when inflicting bodily injuries by other persons. So to argue that someone is safe from brain ailments is impractical. Even a seemingly healthy person can end up in a hospital bed in one minute.
New drug - a chance for survival for many
Fighting in the medical field with cerebral hemorrhages ten years ago was a problem. Most patients died within hours of a hemorrhage. If a closed process of rupture of blood vessels in the brain occurs, then the leakage of blood can reach half a liter. The result is an intracranial hematoma.
Decay products are not excreted, and because of this, many brain cells die completely or partially. Those people who survive after strokes turn out to be incapacitated people with disabilities, and their rehabilitation is very difficult and lengthy. After all, the control center for all the important functional capabilities of the body is the brain, and if it is practically destroyed, then the person becomes completely helpless.
The problem of survival after cerebral hemorrhages has been studied for decades, and ways have been sought to save many patients and return them to a full life. As a result of numerous scientific studies, an ingenious solution appeared of how they can be helped and prevent a high mortality rate. It consists in a new tool developed by medical luminaries. This is the drug Nimotop. Its properties, features and analogues will be described below.
Pharmacokinetic and pharmacodynamic nature of the drug
What does the instructions for use say about this tool? Nimotop is a medicine that has a positive effect on the blood vessels of the brain. According to the pharmacological action, the drug belongs to anti-ischemic and cerebro-vasodilating substances.
Describing the medicine "Nimotop", the instruction says that it has the property of blocking the flow of calcium ions into the cells of the blood vessels of the brain, which reduces their tone and eliminates numerous cramps. After using this product, due to its highly selective effect on blood vessels, an expansion of the arteriole of the brain is observed, which contributes to a significant increase in blood supply to those sites that are prone to deficiency.
The new Nimotop drug, tested in practice, is most often used in the treatment of ischemic cerebrovascular accident. This is today the only effective remedy applicable for a diagnosis of subarachnoid hemorrhage. Thanks to its properties, as already mentioned above, it is possible to reduce the mortality rate among patients.
What else does the instructions for use say? "Nimotop" is a tool that stabilizes the function of nerve cells. It has a nootropic effect on the brain: it improves memory several times, increases the concentration indicator in patients with impaired brain functionality. As a result of this effect, the behavioral reactions of sick people are significantly improved.
The drug "Nimotop" describes the instruction as a fast-absorbing medicine. Once in the body of a sick person, he begins to act in ten minutes. Its maximum concentration in the blood is reached one hour after administration.
The medicine is excreted from the body by the kidneys. The decay time of the active substance included in the composition of the drug is five to ten hours.
Release Forms. The composition of the drug
The drug "Nimotop" (the description also focuses on this) is available in two medical forms.
In pharmacies you can find Nimotop tablets. One package may contain three or ten blisters, each of which contains 10 pills, covered with a yellow shell with the inscription SK. Also sold in a dark glass container. It also has a yellowish tint and is available in 50 ml bottles. This form of medication is intended for infusion.
Pills are still considered more effective. The amount of the active substance nimodipine in them is 30 mg, while in the solution it is only 10 mg. Excipients included in the tablets are microcrystalline cellulose, povidone, corn starch, magnesium stearate, crospovidone. The film coating of the pills consists of yellow iron oxide, titanium dioxide, hypromellose and macrogol. Excipients included in the solution are ethanol, water for injection, sodium citrate, anhydrous citric acid.
The Nimotop solution for use advises against exposure to ultraviolet radiation, since it loses its properties, and is therefore sold in dark glass bottles. Many people look in pharmacies for this medicine in the form of ampoules. However, the instructions for the use of the ampoule do not mention the Nimotop preparation, describing only the solution in bottles and tablets.
Who is prescribed the medicine?
How does the drug recommend using the medicine? Nimotop (solution, tablets) is prescribed for:
- transient ischemic attacks;
- subarachnoid hemorrhages in the brain;
- elimination of the consequences of rupture of the aneurysm;
- a significant decrease in memory (sclerosis), manifested in elderly people;
- emotional instability with nervous shocks;
- intellectual and mnestic disorders.
To whom is this drug contraindicated?
The solution and tablets "Nimotop" the instruction does not recommend taking and prescribing if the patient is not yet 18 years old, or there is an allergic reaction to the components included in the composition of the medicine. Inappropriate administration of the drug during pregnancy (any trimester) and breastfeeding.
Also, the instructions for use "Nimotop" does not recommend taking people suffering from severe forms of liver disease. With special care, medication is prescribed to patients, while an analysis of the condition of the patients is necessarily carried out. Simultaneous administration of Nimotop with antiepileptic drugs, as well as with a substance such as rifampicin, is unacceptable.
Under strict medical supervision, medication is prescribed for patients with arterial hypotension, unstable angina, in the first weeks after myocardial infarction, with severe kidney ailments, alcoholism, impaired alcohol metabolism, as well as epileptics, with severe myocardial ischemia, heart failure, increased intracranial pressure, swelling brain. Taking the drug is accompanied by regular observations by the attending physician.
Methods of using the drug during treatment. Recommended dosage
The medicine "Nimotop" (tablets), the instructions for use recommend that you appoint an infusion solution after the therapeutic course. The pills are swallowed by the patient and washed down with water. No need to bite the pills. Single doses are taken with an interval of four hours.
When the aneurysm ruptures, accompanied by subarachnoid hemorrhage, tablets are prescribed after two weeks of solution therapy. A single dose is prescribed in two tablets for six times a day. The course of treatment is one week.
In cases of impaired brain function, one tablet is prescribed for older adults three times a day. Taking pills is not characterized by any complex features. The dose is always prescribed exclusively by the attending physician. Only a specialist can either increase the dosage of the drug, or reduce it.
The use of solution for infusion is more complicated. It is often prescribed in the first stages of cerebral hemorrhages. One mg of the substance is administered gradually over the course of two hours to patients. If the drug is well tolerated, its dose is doubled. The initial dose for patients with a body weight of less than 70 kg is 0.5 mg per hour. You should know that in its pure form, the Nimotop solution is not introduced into the human body. It is diluted in the following way: 0.9% sodium chloride, Ringer's solution with magnesium, 5% dextrose, a solution of 6% hydroxyethylated starch in a ratio of 1: 4.
The infusion solution is administered during anesthesia, surgery, angiography. The sooner solution therapy is started, the smaller are the effects of negative effects on the brain. The infusion solution is also applicable for preventive purposes. In such cases, he is prescribed no later than the fourth day after the hemorrhage. During surgical intervention, a solution heated to a certain temperature is injected directly into the tanks of the brain. If there is a negative reaction of the body to the administered medicine, its dose is reduced or completely canceled.
When the solution is introduced into the body, medical accessories of brown, yellow, red or black color are used so as not to expose the substance to the negative influence of light. For infusions, only systems with polyethylene tubes are applicable. The medicine "Nimotop" (tablets), the instructions for use recommends taking not only in the exacerbated phases. The solution is a tool to reduce the risk of mortality in complex hemorrhages in the brain.
What side effects can the drug cause?
Describing the medicine "Nimotop", the instructions for use speak not only of its unique properties, but also of possible side effects that may be caused by its use. Doctors always put the benefits of the drug and possible negative consequences on the scales.
How do Nimotop solution and tablets work? Indications for use imply a strict dosage of the drug. During treatment, the following symptoms may occur:
- nausea;
- lowering blood pressure;
- headache;
- itchy skin and rash;
- blood clot formation;
- dizziness and tremor;
- swelling of the body;
- fainting.
Cost of medicine
The medicine is issued by the German company Bayer. The drug is not an inexpensive remedy. So, a pack of one hundred tablets costs around 1200 rubles, a bottle (50 ml) of infusion solution can be purchased for 600 rubles. The drug is not a deficiency, its widespread use in medicine speaks only about high rates of effective effects on the brain.
Analogues of the drug
Many express a desire to replace with cheaper medicines both the solution and the Nimotop tablets. Analogues to them can, of course, be selected from a large list, but it cannot be said that they are equally effective, since the quality of the drugs produced can vary significantly. Doctors recommend using a replacement only in cases where the drug is not suitable for treatment. In doing so, the above recommendations are taken into account.
Similar drugs to replace the Nimotop medicine:
- tablets and Breinal solution (Spain);
- Dilceren tablets (Slovak Republic);
- solution and tablets "Nimopin" (India).
These synonyms, like the original, have the same active substance. It is worth noting that doctors have more confidence in European-made medicines than in Indian therapeutic agents.
Reviews of specialists and patients about the medicine
Thanks to a product such as the Nimotop medicine (many doctors confirm this), it has become possible to save thousands of patients with a diagnosis of cerebral hematoma. Doctors from all over the world have been searching for a solution to the problem for a long time, were in search of means that would allow them to influence the small vessels and capillaries of the brain, penetrate its thin tissues and prevent the death of undamaged parts of the brain center.
Such a tool is designed and has dual benefits:
- resumes activity of the main brain tissue (the so-called neurons);
- It affects the improvement of blood circulation in the brain, saving healthy vessels from the effects of blood vessels damaged during hemorrhage, namely, it localizes pathological changes that lead to human disability.
The drug was developed in the early 90's. It has been researched by many Western European clinics and has received confirmation of its effectiveness. Today, doctors around the world are focusing on this medicine, saving the lives of many people. And we are talking not only about elderly patients, but also about young ones. The indicator of positive shifts during treatment speaks for itself. The medicine “Nimotop” promotes the removal of blood breakdown products from the body and does not allow the situation to worsen until the death. Many medical luminaries, professors and candidates of medical sciences, give this drug an honorable place in the promising areas of treatment of brain ailments associated with circulatory disorders.
Compared to other medicines, Nimotop leads. It is quickly absorbed by the body, penetrates the finest tissues of the brain, while other drugs are mostly powerless. The maximum effect of taking the medicine appears if it is applicable no later than eight hours after receiving injuries to the skull or stroke. A positive effect is noticeable in cases of later administration of the drug.
According to doctors, the main task, namely, protecting the brain from dying, the medicine "Nimotop" performs one hundred percent. Saving human life with its use in medicine has become a reality. Positive responses about the drug relate to its two forms of release - solution and tablets. Observing the conditions for their use, it is possible to bring back to life many people who were previously simply doomed.
Many people positively characterize the Nimotop solution and tablets. Reviews are mainly left by relatives of patients. Using this medication as prescribed by doctors, they notice significant improvements in the restoration of the health of their loved ones. They trace the effect of the drug especially clearly at the moments of rehabilitation of the patient after a stroke, when the processes of movement, thinking, and perception of reality are disrupted.
Preparations of a new generation can extend the life of people and improve at times its quality after suffering complex ailments. Means "Nimotop" is available to everyone today, and its cost does not play a big role when it comes to saving human life. In medicine, more expensive drugs are also applicable. If unforeseen situations occur in life, you need to trust clinically proven medicines, which include the drug Nimotop.
This effective tool is devoted to many articles and scientific developments. The global medical luminaries worked tirelessly in order to eventually receive a unique medicine and be able to return people to a full life without outside help. Hard work paid off by producing an effective drug, the use of which gives a positive effect even in the most seemingly hopeless clinical cases.
This medicine has earned the trust of doctors, patients and their families. Today, it is possible to protect the brain with the most complex physiological defects obtained as a result of trauma, as well as as a result of disruption of cell nutrition.
The use of the drug "Nimotop" is a modern effective practical solution in providing emergency assistance to people. Nothing can characterize a medication as an indicator of the usefulness obtained during treatment of patients.