"Proflosin" is a drug intended for use in problems with urination, which are associated with benign prostatic hyperplasia . This tool is an alpha-blocker.
The active component is tamsulosin, a substance that, acting on the neck of the bladder, reduces its tone, has a relaxing effect on smooth muscles. Such an effect on the body allows you to remove the symptoms of the disease and irritation, and establishes the outflow of urine. The composition contains additional components that enhance the effect of the use of the drug. Consider what the medicine "Proflosin" is. Indications, reviews on its use, effectiveness are presented in the article.
When pain occurs during urination and it seems that the bladder is never empty, while the stream is weak, you need to urgently visit a urologist. Typically, such conditions require the use of Proflosin. Reviews of patients show that the drug can be used, regardless of the stage at which the disease is located.
Release form, composition
The medication is available in the form of capsules, the shell of which dissolves in the intestine. Gelatin capsules, they have a prolonged effect. In addition to the active substance, triethyl citrate, a copolymer of methacrylic acid and ethyl acrylate, cellulose, talc are present in the composition.
Pharmacokinetics, indications
After ingestion, the active component is almost completely absorbed from the digestive tract in a short period of time. This process is disturbed after eating food, in such cases it proceeds more slowly.
As a result of taking the product with the active substance in an amount of 0.4 mg, which corresponds to a single dose, the maximum concentration of the main ingredient in the blood is detected after 6 hours.
Reviews about Proflosin show that it has a good connection with blood proteins - 99%. The drug is characterized by a small distribution of 0.2 l / kg. Metabolism occurs in the liver, this task is performed slowly, after its implementation metabolites are formed. A large part of the drug does not change its shape and enters the bloodstream unchanged.
The active ingredient and the substances resulting from its processing are excreted mainly in the urine, while a small part of the drug (9%) is eliminated from the body unchanged. If the drug was taken after a meal, elimination half-life is carried out in ten hours, if its use is regular - in 13 hours.
Reception of the Proflosin drug is allowed by doctors and patients for dysuric disorders that develop against the background of prostatic hyperplasia (benign character).
Contraindications
The medicine is contraindicated in case of hypersensitivity to its components. Treatment with this agent is not recommended for orthostatic hypotension, even in the anamnesis. You should not take the drug in the presence of arterial hypotension, severe liver failure. If treatment is prescribed to a patient with chronic renal failure, when the QC is less than 10 ml / min, careful monitoring by a doctor is required.
The use of the drug, the choice of dosage
"Proflosin" patient reviews, instructions recommend taking once a day. The product must be used after the first meal. One capsule must be swallowed without violating its integrity. It is necessary to drink medicine well. Dividing the capsule into parts may interfere with the absorption rate of the active ingredient. The course of treatment is not established, the drug is taken as necessary, the treatment period is not limited.
Side effects
Violations in the digestive tract, in the nervous system may occur. Possible damage to the reproductive system, heart and blood vessels. During treatment, you can notice changes in the skin and tissues located under the skin.
A man can find problems with ejaculation, in very rare cases, patients develop priapism. Perhaps a significant deterioration in well-being, when there is a headache, dizziness, sometimes a person is in a fainting state.
After taking Proflosin, patient reviews note that angioedema occurs from skin manifestations , urticaria, itching of the skin develop, and a rash appears. But this happens very rarely. A person can suffer from diarrhea and constipation. It is likely that nausea with vomiting, hypotension (orthostatic), and tachycardia will be added to side effects.
In a few cases, narrow pupil syndrome develops as a result of cataract, rhinitis, asthenia removal.
Cases of overdose have not been recorded. But theoretically there is such a possibility. With an overdose of the drug, blood pressure may decrease, tachycardia may occur. To normalize the pressure, heart rate, you need to lie down a bit. It is pointless to prescribe hemodialysis to the patient, since the active component of the drug binds very well to plasma proteins. Requires the implementation of actions that will stop the absorption of the drug - gastric lavage, the use of an osmotic laxative or activated charcoal.
special instructions
When signs of orthostatic hypotension appear, such as weakness, dizziness, the patient is laid or seated, the necessary manipulations are performed.
Before starting therapy, during which it is planned to use the Proflosin medicine, the patient is primarily interested in the use, composition, and reviews, but special instructions for its use also deserve attention and help not to harm health even more. Starting therapy, you need to be sure that the patient does not have conditions whose symptoms are similar to prostate damage - benign hyperplasia.
Before treatment and during its implementation, regular digital rectal examination is necessary, if necessary, determining the level of PSA.
With the development of angioedema, the drug is canceled and re-prescribed. In the presence of cataract and the operation to remove it, taking Proflosin can lead to narrow pupil syndrome. To exclude this result, the surgeon must perform special preoperative preparation, the operation must also be carried out correctly.
When treating with Proflosin, patient reviews recommend caution when driving and engaging in activities that may be life-threatening with decreased attention span and psychomotor reactions, as dizziness sometimes occurs.
Drug interaction
As a result of taking the drugs "Teoffillin", "Nifedipine", "Enalapril", "Atenol" there is no interaction with tamsulosin.
With the simultaneous use of the drug with "Cimetidine" there is an increase in the level of the active substance tamsulosin in the blood. "Warfarin", "Diclofenac" contribute to the faster elimination of tamsulosin from the body. When combining the drug "Proflosin" with similar drugs, a decrease in blood pressure is possible.
When combined with Furosemide, a decrease in the concentration of the active component of the drug is observed, however, in this case it is not necessary to increase the dose of Proflosin, since after reducing the concentration the active substance maintains a normal dose sufficient for therapy with the Proflosin drug. Reviews, instructions, price, description - all this information matters when choosing a particular drug for treatment. Consider the reviews left by doctors and buyers, find out the approximate cost of the drug.
The cost of the drug, analogues
Before using Proflosin, the price, instructions, reviews in most cases are carefully studied by the patient. The cost of one package of capsules is approximately 400-500 rubles.
Of the analogues can distinguish "Revocarin" and "Tulosin." Other substitutes of the drug are also known, for example, Fokusin, Omnic.
Reviews
Having read reviews about the drug, we can talk about its high effectiveness. Basically, the reception of "Proflosin" is carried out by men after 50 years, when prostate disease develops. Many patients are satisfied with the result of treatment, in most cases, problems with urination disappear or are less painful for a man.
Of the side effects, problems with an erection, tachycardia and a decrease in blood pressure are sometimes observed. Proflosin did not help some patients, so they had to decide on an operation.
Many doctors choose this drug for treatment only if they are sure that their prescriptions will be strictly followed by the patient. Experts argue that the need for surgery can be eliminated if the patient correctly uses (regularly and at a certain time) the drug "Proflosin". Reviews, instructions, analogues, application, price are now known to you, and, after consulting with your doctor, you can start treatment. The specialist will conduct an examination and prescribe a certain dose of medication, which should help in a particular case.