One of the highly effective means for restoring joint function is the Fermatron drug. The analogs of this medication have also proven themselves well.
Drug characteristics
"Fermatron" is a visco-elastic agent, which is intended for introduction into the synovial space of the affected joints. The main active ingredient in it is sodium hyaluronate in phosphate buffer. This product is produced by the Scottish company Hyaltech Ltd.
This substance can be called an artificial prosthesis. After all, with the right introduction, it replaces the synovial fluid in the joint. It is necessary to reduce friction between parts of the joint and to nourish cartilage tissue. Sodium hyaluronate is obtained by fermentation and thorough purification of Streptococcus equi bacteria.
On sale you can find several types of this tool. Sell the solution "Fermatron", "Fermatron C", "Fermatron plus." Analogs, the price of which will be slightly more affordable, it is better to choose only with a doctor.
Indications and contraindications
Prescribe drugs based on sodium hyaluronate in those situations when it is necessary to anesthetize and improve joint mobility. This tool is capable of:
- eliminate pain;
- stimulate the synthesis of natural hyaluronate;
- return joint mobility;
- protect cartilage.
This drug, like any other analogue of Fermatron, is prescribed for stiffness, pain in the knee or other joints. As a rule, it is recommended for patients with moderate or mild osteoarthritis, which are caused by traumatic injuries or degenerative changes.
But it can not be used with:
- confirmed hypersensitivity to the components of the drug;
- damage or inflammation of the skin at the intended injection site;
- acute synovitis - inflammation of the synovial membrane (first you need to stop this condition).
Also, contraindications include childhood.
Pharmacological properties of the drug
To restore the visco-elastic properties of joints, as well as the protective functions of intraarticular fluid, you can use the means of "Fermatron". Its analogs are also intended to achieve these goals.
Preparations based on hyaluronate are able to reduce inflammatory reactions in joints, increase their mobility, and relieve pain. They also actively restore the structure of the cartilage tissue of the joints.
The use of this group of drugs in osteoarthritis and after arthrocopic interventions is shown. To achieve the desired effect, it is recommended that drugs be administered in a course consisting of 3-4 injections. Injections are done at intervals of 7 days.
Possible analogues
Many are interested in how to replace the "Fermatron" tool. Cheap analogs are hard to find. But there are remedies that can also replace synovial fluid in the joints. These include not only drugs manufactured by the same company Hyaltech under the names "Fermatron plus" and "Fermatron C".
You can also replace them with Ostenil, Gialux, Sinocrom, Dyuralan, Suplazin. They are also available in disposable syringes with different volumes. The main active ingredient in them is sodium hyaluronate. It is inserted into the synovial bag of the problem joint.
But you should not choose a remedy yourself without consulting a specialist. Also, the doctor, depending on which joint the drug will have to be injected, selects the desired volume and dosage.
Price policy
On sale you can find several options means "Fermatron". Analogs (the price for them differs markedly) under the name "Fermatron plus" or "Fermatron C" are more expensive. If the usual solution in a 2 ml syringe can be found for 3900 rubles, then for "Fermatron C" (3 ml) you will have to give about 14 000 rubles. The first drug is 1%, it contains 20 mg of the active substance, and in the second, the concentration of sodium hyaluronate is already 2.3% - 69 mg. In the syringe marked “plus” with a capacity of 2 ml is 30 mg of sodium hyaluronate.
An analogue of Fermatron called Dyuralan costs almost 19.5 thousand rubles. A 3 ml syringe contains 60 mg of active substance. The Sinokrom mini tool is noticeably different in price. It costs 2300 rubles, but the syringe contains only 1 ml of a 1% solution, that is, 10 mg of the active substance.
A little cheaper means "Fermatron" drug "Ostenil". The usual 2-ml syringe of 1% sodium hyaluronate will cost 3,700 rubles. Approximately also there is another analogue of “Fermatron” - “Giallux”. In the same price category is the tool "Sinokrom". A syringe with 2 ml of a 1% solution will cost 3900 rubles. The drug "Sinokrom forte" consists of 2% sodium hyaluronate, it costs a little more than 6000 rubles.
Features of use
Only medical personnel who have undergone special training can administer the Fermatron drug to patients. Analogues of this tool must be used in compliance with the same requirements. All of them are intended only for one injection.
This product is sold in a special syringe, packaged sterile. Therefore, with any damage to its integrity, the drug cannot be used. Also, when prescribing this agent, it is necessary to take into account the possible risk that is potentially present during the injection of any biologically active substances. Do not forget about the possible immunological effects.
The introduction is possible only in a room equipped for intraarticular injection. In this case, antiseptic rules must be strictly observed. The injection site is treated with alcohol or an appropriate antiseptic.
For the treatment of knee or hip joints, it is possible to use drugs with a volume of 2 ml or more, depending on the severity of the disease. For the treatment of smaller synovial spaces, you can use the analogue of "Fermatron" called "Sinocrom mini" and its substitutes.
Features of Dyuralan
This drug is available in 3 ml syringes. They contain a 1% solution of sodium hyaluronate. The buffer in this product is saline solution of sodium chloride, the pH of which is 7. It looks like a viscous, transparent, elastic gel. They can notice the "Fermatron plus". Analogs, the price of which will be more affordable, are difficult to find. But most often it is used instead of the drug "Fermatron C". After all, the concentration of the active substance in these preparations is almost the same.
The drug "Dyuralan" in the body disintegrates in the same way as ordinary hyaluronic acid, which is part of the synovial fluid. It provides lubrication of the ligaments, cartilage and serves as an absorbing barrier during shock loads.
Patient Reviews
Most often, doctors recommend making several injections with a 1% solution of hyaluronic acid. This is necessary to achieve a therapeutic effect.
Therefore, the indicated drug itself or other analogues of Fermatron are mainly prescribed. Prices, reviews are those points that you should pay attention to before buying. Doctors say that they don’t see the fundamental difference between the drugs manufactured by different pharmacological corporations. Patient opinions may vary slightly. But it is difficult to find people who injected several drugs and can evaluate the effectiveness of each of them.
Patients confirm that mobility is restored after several injections. Some say that mobility improves, but pain does not completely disappear. Although others say it is an excellent analgesic effect.
It is also worth saying that for many patients, discomfort returns over time. Such reviews are left by both those who used the Fermatron analogue and those who were injected with a Hyaltech LTD drug.
Important Nuances
The need to verify the integrity of sterile packaging and compliance with all antiseptic standards with the injection of funds into the joint is obvious. But there are other points worth remembering.
For example, with a needle inserted into the hip joint, local anesthesia is desirable . But it can also be used if necessary to inject in other synovial spaces. The procedure itself is preferably carried out under ultrasound or fluoroscopic control.
In some cases, it is necessary to pre-aspirate the articular effusion. For this, the same needle is used, which is intended for the introduction of Fermatron Plus. Analogs of this drug are used in the same way.
One must be prepared that intra-articular administration of the drug can cause a slight pain, which passes over time, swelling. If the patient has inflammatory osteoarthritis, then the pathological process after administration of the drug may intensify. But this will only be a temporary phenomenon.