In the mid-20th century, drugs were developed in medicine that could fight infections. These are antibiotics. A lot of time has passed, but people still need these effective drugs. When taking Doxycycline, the instructions for use are very important to avoid improper use.
Doxycycline - indications for use
According to WHO, in the world every year about 1 billion. people suffer from infectious diseases. Of course, epidemics of smallpox, plague, and cholera are a thing of the past. But people nowadays die from pneumonia, sepsis. New infections appeared - chlamydia, mycoplasmosis, urogenital ureaplasmosis. Therefore, medicine needs broad-spectrum antibiotics such as doxycycline. Instructions for use in each individual case should be studied very carefully.
Broad-spectrum antibiotics include doxycycline, a tetracycline antibiotic. The action of doxycycline is based on the bacteriostatic effect. The drug penetrates almost all tissues and fluids, into bile, and accumulates in bones, teeth, liver cells, and eye tissues. Hence the therapeutic effect of the antibiotic. The effectiveness of chlamydia is 95-100%, doxycycline is an indispensable drug in the treatment of this disease.
The drug Doxycycline is also used for genital infections, prostatitis in men, with tick-borne borreliosis or Lyme disease, gastrointestinal infections. Indications for the use of doxycycline are also bacterial pneumonia, bronchitis, eye diseases, it is used in dentistry, in the treatment of diseases of the urinary system.
Antibacterial therapy is carried out for a sufficiently long time, so the drug is released in such dosage forms that are more safe for the body.
The most common doxycycline hydrochloride gives many side effects, up to the development of erosive and ulcerative esophagitis. Currently, doctors use doxycycline monohydrate, which does not irritate the mucous membrane of the digestive tract. This drug can be taken in the form of tablets, as well as suspensions - the treatment becomes more comfortable.
Contraindications
Do not take the drug for people with hypersensitivity to doxycycline. Hypersensitivity can be manifested by suffocation, the appearance of rashes, swelling, and an increase in body temperature. Contraindications for the use of doxycycline are porphyria, severe chronic renal failure, pregnancy (especially in the second or third trimester), lactation. To avoid undesirable manifestations when taking Doxycycline, the instructions for use should always be next to the drug itself.
Side effects of doxycycline
From the CCC and blood: eosinophilia, neutropenia, a decrease in the prothrombin index.
From the central nervous system: nausea, vomiting, dizziness.
Allergic reactions: sometimes an urticaria rash, Quincke's edema, less often anaphylactic shock.
Dosage and administration
Doxycycline is prescribed to adults orally or intravenously (drip) at a dose of 200 mg per day on the first day, then 100 mg 1-2 times a day. Duration of administration is 7-10 days. Doxycycline is prescribed for children over 8 years of age in a dose of 2-4 mg / kg. The dosage depends on the severity of the disease, the type of pathogen and is prescribed individually by the attending physician. Doxycycline is taken after a meal with a large amount of water.
Drug interaction
The effect of the drug is reduced by antacids, foods containing calcium, iron preparations, especially sodium bicarbonate, magnesium laxatives, so doxycycline is taken 3 hours after taking these funds.
When combined with various bactericidal antibiotics, their effectiveness decreases.
Barbiturates, rifampicin, carbamazepine reduce the concentration of doxycycline (most often) in blood plasma.
Retinol in combination with doxycycline increases intracranial pressure. Do not forget that this is a powerful drug - doxycycline. Instructions for use should in no case be lost.
The drug from the pharmacy is dispensed only by prescription.
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