Does Acne Retasol Help? Reviews of those who have ever used this tool will be presented in this article. Also in it you will find information about the composition of the mentioned medication, its features and contraindications.
Form and composition of the drug
In what form is the drug "Retasol" sold? Reviews report that this tool can be purchased in the form of a 0.025% solution intended for external use. It is available in 50 ml glass bottles made of dark glass, which are placed in cardboard packaging.
The active substance of this drug is isotretinoin. It also contains butyl hydroxyanisole, ethyl alcohol and butyl hydroxytoluene.
Pharmacological features of a medical device
What is the use of Retasol solution for? Reviews say that the drug in question is intended to treat acne. It normalizes the terminal differentiation of cells, slows down the hyperproliferation of the epithelium of the sebaceous glands, or rather their excretory ducts, and promotes the formation of detritus, greatly facilitating its evacuation.
Due to this effect of the medication, the production of sebum significantly decreases in the patient, its composition is normalized and excretion is facilitated. Also, the use of this tool reduces inflammation around the sebaceous glands.
With systemic and external use, the solution in question has anti-inflammatory, sebostatic, antiseborrheic, immuno-and keratomodulating effects. In addition, it enhances the regeneration of the skin.
Kinetic properties of the drug
When taken orally, isotretinoin is well absorbed from the digestive tract. In this case, absorption may increase if the drug was taken with food.
The peak concentration of the active substance of this agent in blood plasma is reached after 4 hours.
The bioavailability of isotretinoin is low. This is due to its parietal metabolism in the intestinal walls, as well as the "first passage" through the liver.
The active substance of the agent in question is highly bound to plasma proteins. It is metabolized in the liver with the formation of the main derivative - 4-oxo-isotretinoin. In the process, partial isomerization of isotretinoin to tretinoin occurs.
The final half-life of tretinoin is 12-20 hours. An equivalent amount of this substance is determined unchanged in the feces, as well as in the form of metabolites in the urine.
As for the local use of isotretinoin, in this case its systemic absorption is small.
Indications for use
What is the medicine "Retasol" used for? Customer reviews report that such a solution for external use copes well with papular-pustular acne, seborrhea, rosacea, and perioral dermatitis.
Prohibitions for the appointment of an external solution
In what cases can not use the drug "Retasol" for acne? Reviews say that when applied topically, the drug in question is not absorbed into the systemic bloodstream. But, despite this, it is not recommended to be used during pregnancy, with increased sensitivity to the main substance, lactation and the simultaneous use of antibiotics belonging to the tetracycline group.
It cannot be said that oral medications containing isotretinoin are contraindicated for use in severe disorders in the functioning of the liver and kidneys, elevated blood lipids, hypervitaminosis A and various neoplasms.
With caution, the medication in question is prescribed for chronic pancreatitis, decompensation of cardiac activity, liver and kidney diseases, as well as chronic alcohol intoxication.
How should I use the drug "Retasol"?
Reviews (a photo of this tool is presented in this article) experts report that the use of this medication should only be indicated.
The solution for external use is applied to the skin with a cotton swab. In this case, the affected area is pre-cleaned with any cosmetic product without alcohol.
How long should Retasol (solution) be used? Reviews say that the duration of treatment with this tool is 4-12 weeks. If required, then after consultation with a dermatologist, a second therapy can be performed.
With an exacerbation of the disease and the development of adverse reactions at 1 or 2 weeks of treatment (for example, with the appearance of itching, redness, new rashes, swelling of the skin), the use of the medication must be stopped until all negative symptoms subside. After some time, treatment can be resumed.
According to the attached instructions, this drug should not be applied to the mucous membranes, as well as skin areas located near the visual organs.
Side effects
What are the negative effects of Retasol? Reviews say that against the background of using this drug, patients often develop local allergic reactions in the form of edema and itching of the skin, hyperemia, papular rash, headache, photosensitivity and excessive fatigue.
Interaction and Overdose
What are the symptoms of overdose caused by Retasol? The reviews of experts report that at the moment they do not have such information.
The simultaneous use of isotretinoin with other retinoids (for example, Adapalen, Tretinoin, Acitretin, Retinol) significantly increases the risk of hypervitaminosis A.
This drug is not allowed to be used in conjunction with tetracyclines, as this causes a significant increase in intracranial pressure.
The medication in question weakens the effect of progesterone. In this regard, during its use should not use contraceptives containing this hormone.
The drug "Retasol" together with drugs that increase photosensitivity (tetracyclines, thiazide diuretics or sulfamides), significantly increases the risk of sunburn.
Special information
During treatment, the drug in question should not be treated by patients. Moreover, patients are advised to avoid direct exposure to sunlight.
When treated with Retasol, the patient may experience intolerance to contact lenses.
The safety of the use of this solution in children and people of prepubertal age has not been established.
Analogs, cost
Does Retasol help with wrinkles? Reviews claim that this medication has no effect on age-related skin changes. It is intended only for the treatment of skin diseases, including acne.
If necessary, the drug in question can be replaced by such means as Retinoic ointment, Dermoretin, Roaccutane or Isotrexin.
The price of Retasol solution in the pharmacy chain varies between 410-470 rubles per bottle.
Medication "Retasol": reviews
It tightens pores and eliminates acne eruptions - almost all reviews that Retasol consumers put aside this information.
The acne medication in question is a very popular drug. Patients claim that he is able to remove blackheads on his face in just two weeks. However, some reports say that the effect of this drug is very slow. In addition, it strongly bakes and dries the skin.
As for doctors, they claim that Retasol has high therapeutic efficacy. Especially fast it affects oily skin.
With severe acne, experts recommend using the Retasol solution together with other antibacterial agents or anti-acne drugs.