The drug "Tsifran ST" acts as a broad-spectrum antibiotic. Its main advantage is that it is very fast. This medication belongs to the group of quinolones. It copes well with chronic infectious diseases and is considered effective in the fight against various bacteria. To achieve the desired result, only two weeks of treatment are required. Next, we will consider in detail the instructions for the "Tsifran ST", and also find out what analogues it has and what citizens write in their reviews about its use.
The composition and form of the release of the drug
Tablets of the presented drug are produced in a dosage of 500 or 600 milligrams. In this medicine there are two main components, which are ciprofloxacin and tinidazole. Sodium lauryl sulfate along with titanium dioxide, microcrystalline cellulose, talc, lactose monohydrate, and iron oxide serve as excipients.
Drug properties
This drug is a combination antibiotic. The properties of Cifran ST are determined by two main components: tinidazole and ciprofloxacin. The main component of tinidazole actively copes with anaerobic microorganisms, gram-positive bacteria, spore-forming parasites, peptostreptococci and peptococci and so on.
According to the instructions for use with Cifran ST, ciprofloxacin, in turn, is an antibiotic in a wide range of applications. It is very effective against a large list of all kinds of aerobic bacteria, which are Escherichia coli along with Klebsiella, which is the causative agent of pneumonia. Also, this active substance is used to treat typhoid fever and other pathologies that are caused by salmonella. Ciprofloxacin is especially effective in the fight against Pseudomonas aeruginosa and hemophilus bacillus, and is also able to defeat gonococci, Staphylococcus aureus, pneumococcus, chlamydia, mycoplasma and so on.
Both active components undergo a process of their absorption in the human digestive system. After a couple of hours, the maximum concentration of these substances in the blood is reached. The half-life of tinidazole is up to fourteen hours. This substance is exported to bile. About a quarter of the total amount of tinidazole goes with urine. A small portion of tinidazole can be excreted in the feces. Ciprofloxacin, in turn, is absorbed quickly enough in the body. In the event that the drug was taken with food, then absorption is slowed down by about thirty percent.
This drug quickly spreads through the tissues of the body. About half of the total amount of medication taken is absorbed by the liver. The remaining fraction leaves the body unchanged. The elimination half-life lasts about four hours. In elderly patients, as well as in those who suffer from kidney failure, the elimination period is delayed.
When should a medication be taken?
The reason for the appointment of the patient "Tsifran ST" may be the following diseases and conditions:
- The presence of infectious diseases of the respiratory system. In this case, we are talking about pneumonia, acute bronchitis and inflammatory processes of the bronchial mucosa. It is also advisable to use this medication against the background of acute inflammation of the walls of the bronchioles, with lung abscesses and the like.
- The appearance of otolaryngological diseases of an infectious nature, for example, with sinusitis, which is a lesion of the mucosa of the paranasal sinuses.
- The appearance of urinary tract infections.
- The occurrence of infections of the reproductive system.
- In diseases transmitted through sexual contact.
- In the presence of gonorrhea, the causative agent of which is gonococcus.
- The presence of certain inflammatory processes in the pelvic organs.
- The development of infectious lesions of the digestive system, for example, it is advisable to use this medication for peritonitis, when the parietal and visceral sheet of the peritoneum is inflamed.
- The presence of cholecystitis, which is inflammation of the gallbladder.
- The development of cholangitis is a disease of the bile ducts. In addition, “Tsifran ST” is prescribed for empyema of the gallbladder, which occurs as a complication of acute cholecystitis.
- The presence of typhoid fever.
- With any severe purulent and inflammatory processes in the joints.
Instructions for use of the drug
As the instructions to “Tsifran ST” indicate, it is necessary to take the medication presented only after eating. Swallow the tablet completely, it is important to note that it is undesirable to violate the integrity of the shell. In most situations, the treatment regimen is the same. As part of the treatment, one tablet is used. The duration of treatment is determined by the attending physician. Often, the duration of treatment lasts from seven to ten days. In the event that the disease is severe, the duration of therapy can be increased.
This also tells us the instruction. Reviews about "Tsifran ST" are abundant.
Drug overdose
In the event that after the procedure vomiting occurs along with dizziness, indigestion, kidney failure and arrhythmia, this is a sure sign that an overdose has occurred. The first thing in this situation is to reduce the amount of the drug, which is found in excess in the body. To do this, wash the stomach. You can also try to induce vomiting. To cause a vomiting reflex, you need to press your fingers on the root of the tongue.
After the procedures, you will need to take intestinal sorbents, and, in addition, carry out symptomatic treatment. It should be noted that there is no specific antidote for the drug.
Contraindications to the use of the drug
In accordance with the instructions for use with "Tsifran ST", there are some physiological and pathological contraindications for the purpose of the presented drug, they are as follows:
- The presence of porphyrin disease. Often this ailment is a hereditary disorder of pigment metabolism, against the background of which an increased content of porphyrins in the blood develops.
- The presence of a pathology of the blood system. It is worth noting that even if such a disease was transferred once before, this is still an occasion to pick up one of the analogues.
- The presence of organic pathology of the nervous system. Against the background of this diagnosis, various pathological changes occur in the substances of the brain.
- The presence of pathological inhibition of the hematopoiesis process in the region of the bone marrow.
- Until the age of eighteen, this drug is strictly contraindicated.
- Pregnancy at any time serves as a reason for refusing to take this drug. In this case, it is advisable to select a more gentle analogue if necessary.
- During breastfeeding, according to the instructions, "Tsifran ST" 500 mg is also not suitable for use.
I must say that severe atherosclerotic lesions of the brain are not considered a contraindication, but with such a disease, it is necessary to treat the medicine with great care. In addition, certain cerebrovascular diseases of various genesis, along with mental abnormalities, seizures and old age, require careful use of the drug presented.
Side effects of taking a medication
According to the instructions for use and reviews of "Tsifran ST", while taking this medication, a decrease in the level of leukocytes along with a decrease in the content of granulocytes in the blood is likely. Anemia, an increase in platelets, and, in addition, a change in the cellular composition in the blood are not excluded. A decrease in the number of neutrophils may also be noted. As adverse reactions, the processes of inhibition of bone marrow hematopoiesis are launched, the lumen of the blood vessels increases, which is due to a decrease in muscle tone.
- The nervous system usually responds to this drug with migraines, dizziness, impaired coordination, weakness, depression, and uneven gait. Violation of speech and sleep is not excluded. The occurrence of anxiety, increased pressure and the development of thrombosis are likely.
- Possible respiratory failure.
- The cardiac system can respond to ventricular arrhythmia. It is also likely to observe a rapid heart rate.
- The digestive system can respond by impaired appetite, dry mouth, nausea, diarrhea, cholestatic jaundice, gallbladder inflammation, hepatitis or hepatonecrosis.
- The activity of the musculoskeletal system may be accompanied by joint pain, which will be volatile. In addition, inflammation of the joints and tendons of the muscles is not excluded. In addition, tendon damage can be observed along with muscle weakness and increased symptoms of myasthenia gravis.
- The work of the urinary system may be accompanied by the formation of salt crystals in the urine, glomerular nephritis, malfunctioning of urination, increased urine formation and inhibition of the nitrogen excretory functions of the kidneys.
- There may be a malfunction in the taste buds. The appearance of pronounced photosensitivity is likely, tinnitus may appear along with partial hearing loss.
- As an allergic reaction to the drug, patients may experience itching, various redness, the occurrence of bleeding blisters or swelling of the face. Vascular wall inflammation may also be noted along with shortness of breath and anaphylactic shock.
- While taking this drug, laboratory indicators can record an increased amount of sugar along with hyperbilirubinemia.
Among other things, against the background of treatment with the Cyfran ST antibiotic, candidiasis and excessive sweating are possible.
Drug interaction
It should be borne in mind that tinidazole contained in the composition is able to increase the effect of indirect anticoagulants and ethanol. In addition, this medicine does not get along well with a drug called Ethionamide. The substance phenobarbital accelerates the metabolism, therefore, the maximum concentration of Cyfran ST in plasma in combination with the intake of this substance occurs much faster. The presented drug does not interfere with the work of other antibiotics.
Ciprofloxacin can slow the half-life of theophylline and oral medications that lower blood glucose. In combination with antimicrobials, an increase in the effects of both drugs can most often be observed, which should be considered when prescribing a dose.
Iron-containing drugs and antacids help reduce absorption. In this regard, between such medicines it is required to withstand a pause of at least an hour. Painkillers, anti-inflammatory and antipyretic drugs in combination with "Tsifran ST" provoke convulsions. The medicine "Metoclopramide" is able to reduce the absorption time of ciprofloxacin, as a result, the maximum concentration is reached faster.
The combination with Omeprazole is able to reduce the content of Cyfran ST in the blood. The complex of "Probenecid" and ciprofloxacin increases the content of the second in blood plasma, slowing down the excretion process. Side effects of the drug “Ropinirol” can occur in an increased form in the case of a combination of this drug with ciprofloxacin.
Drug Analogs
Among the analogues of "Tsifran ST" it is worth mentioning the following medicines:
- The drug "Alzipro". This analog is antimicrobial and has a wide range of effects. This tool is highly effective in fighting bacteria.
- The medicine "Afenoxin." It is usually prescribed to combat pathogenic microbes.
- The drug "Basigen." His doctors usually prescribe for a quick fight against a bacterial infection.
- Betaciprol medication is effective in the fight against bacterial diseases.
- The drug "Vero-Ciprofloxacin" also works great against bacterial infections.
- The medicine "Zindolin" is often prescribed against generalized infections.
- The drug "Ifipro" is an antimicrobial drug of wide action.
- The drug "Tsifran" acts as a direct analogue and differs from it only in dosage. Cifran contains 250 milligrams of ciprofloxacin and 300 milligrams of tinidazole. All other characteristics completely coincide with "Tsifran ST".
The price of the drug described by us is approximately three hundred rubles.
Special instructions for the use of this drug
According to the instructions for the Tsifran ST antibiotic, when taking this drug, urine can often turn dark, which in no way affects the health of the body. In the case of epilepsy, seizures, and, in addition, problems with the vessels, this medicine should be taken only in extreme cases and under the strict supervision of a specialist. In case of diarrhea, the first thing to do is to exclude the development of pseudomembranous colitis, in which the tablets "Tsifran ST" are contraindicated.
It is not recommended during the treatment period with this tool to stay in the open sun for a long time, since in this case phototoxicity may occur. It should be borne in mind that the medication is incompatible with alcohol. As a result of drinking alcohol, spasms and vomiting may occur.
Reviews about "Tsifran ST" from patients
People write that they use this tool in case of various abscesses, barley, bacterial diseases and so on. It is reported that against the background of its use, no side effects have been identified. Patients say that just one week is enough for the symptoms of the disease to go away. But given the fact that it is an antibiotic, patients still use it with caution.
Many people write in their reviews that they drink Cifran ST 500 mg as an antiviral agent. True, in this case, a side effect such as nausea is reported. And the rest is told that these pills are fairly easy to carry, and the drug itself is actually effective. In particular, it is noted that he literally in a matter of days can put a person on his feet, even against the background of a severe course of the disease.
Thus, in general, the reviews report that “Tsifran ST” is a very good antibiotic. People are prescribed treatment for various bacterial diseases. Therefore, in many ways, the tool is universal. But, of course, you cannot just appoint it yourself, but first you need to consult a specialist.