The article will present reviews about Norkolut in endometrial hyperplasia. The medical product belongs to the category of gestagen-containing medicines and is used in the field of clinical gynecology.
Composition and form of release
This pharmacological preparation is made in the form of white tablets for oral use, which are packaged in 10 pieces in blisters and in cardboard boxes of 2 blisters, with a detailed description of the drug inside.
Each tablet contains 5 mg of the active element - norethisterone, as well as a number of additional components: potato starch, magnesium stearate, colloidal silicon dioxide, talc, gelatin, corn starch, lactose monohydrate.
Reviews about Norkolut are abundant.
pharmachologic effect
The medicine is able to influence the state of the uterine mucosa, supporting it in the state of the premenstrual (secretory) phase. The active substance of this medication blocks the production of specific pituitary hormones, which prevents the maturation of new eggs and their exit from the ovaries. In addition, the medicinal product actively reduces the tone of the muscle layer of the uterus and stimulates the growth and development of the milk ducts and glandular tissue in the chest, preparing the glands for the lactation process in the postpartum period.
Women's reviews of Norkolut are mostly positive.
Indications for appointment
The use of this drug is indicated in the treatment of the following pathological conditions and diseases:
- premenstrual syndrome;
- violation of the cycle - algodismenorea (painful menstruation), or amenorrhea (absence of menstruation);
- diseases of the mammary glands - mastodynia, mastopathy (proliferation of glandular tissues);
- uterine diseases - myoma (a tumor developing in the muscle layer of an organ of a benign nature), endometriosis (reproduction of cells of the inner layers of the uterus, when endometrial cells are found in the ovaries, bladder, intestines, etc.);
- endometrial hyperplasia (thickening and proliferation of the inner membranes of the uterus, which can trigger the development of an oncological process);
- menopause.
In addition to the above indications for use, a pharmacological agent is used to stop lactation, as well as a contraceptive.
This is stated in the instructions for use with Norkolut. We will consider reviews below.
Dosage and administration regimen for various pathologies
Since this drug is made in the form of tablets, it should be taken orally, that is, inside. Reception does not depend on the time of eating.
In the treatment of premenstrual syndrome, the Norkolut medicine is taken 1 time per day, 1 tablet, from 16 to 25 days of the menstrual cycle.
If the menstrual cycle is disturbed (algodismenorea, amenorrhea), the dosage of the medication does not change, and it is taken at the same time. According to the same scheme, Norkolut is prescribed for pathologies such as mastopathy and mastodynia.
With the development of uterine fibroids, the Norkolut medical device is prescribed for a long period, but it can not be taken for more than months. Reception starts from the 5th day of the cycle and ends on the 25th day. The daily dosage is 1-2 tablets.
With the development of endometriosis, this pharmacological drug is taken according to the same scheme that is prescribed for myoma, however, the daily dosage should not be more than one tablet. Another treatment regimen is also possible: 1 tablet per day 10 days a month, from day 16 of the cycle. The therapeutic course according to this scheme can be extended up to a year.
According to women, Norkolut is very effective.
With endometrial hyperplasia, the medication is taken in a short therapeutic course: 6-12 days, 1 tablet per day. To achieve the desired effect (stopping bleeding), the use of the Norkolut medication must be continued at the same dosage for prophylactic purposes, from the 16th to the 25th day of the cycle. In this case, any drug containing estrogen can be simultaneously prescribed.
There are also reviews of women about Norkolut after 40 years.
With menopause, as well as in women after the age of 40, this pharmacological agent is taken for a long course, the daily dosage is one tablet.
Taking the medication for 12 months in a continuous mode is possible, but only during therapy in the treatment of menopausal disorders. Abrupt drug withdrawal does not cause any negative consequences, however, in such a case, it is necessary that the specialist prescribe another medication. Treatment should be carried out under the supervision of a doctor who individually selects the dose and duration of therapy.
Reviews about the use of Norkolut are of interest to many.
Contraceptive regimen
The medication can be used for contraception. This technique is carried out according to the following scheme: 1/2 - 1/4 tablets at bedtime, lasting three weeks, starting from day 5 of the cycle. After this, you need to make a seven-day pause, after which the medication continues. At the beginning of use as a contraceptive, this medication requires its combination with estrogen intake (the doctor prescribes specific drugs).
This is confirmed by the instruction. According to reviews, Norkolut reliably protects against unwanted pregnancy.
Menstruation
This pharmacological drug can be used to call and delay periods. In the first case, the medicine is used according to the following regimen: 2 tablets per day - 5 days. After this, the medication is stopped, which will trigger the onset of menstruation. In this case, the woman must be sure that the delay in menstruation is not associated with the onset of pregnancy. By causing menstruation in a similar way, you can upset the menstrual cycle, so you can’t do this without emergency. To delay the period, this medication is prescribed 8 days before the expected day of their onset, and it should be taken 12 days, 2 tablets per day (at one time). This scheme provides a delay of menstruation for 7-10 days. In some cases, after this, the occurrence of heavy bleeding. According to reviews, "Norkolut" monthly periodically delays if necessary, which is very convenient.
During pregnancy and lactation
During pregnancy, this pharmacological drug is prescribed only in case of a threat of spontaneous miscarriage. In other cases, the presence of pregnancy is considered a direct contraindication for the use of Norkolut. The practice of using this medication to stop or prevent the lactation process after childbirth is also practiced, since it tends to reduce the production of mother's milk in the postpartum period. It can be prescribed in cases when feeding for certain reasons is undesirable or a nursing mother decided to stop the lactation process. For complete cessation of milk production, Norkolut is taken 3 days, 1 tablet 4 times a day, then 4 days, 1 tablet 3 times a day, and another 3 days, 1 tablet 2 times. This ends the therapeutic course, and lactation should stop.
To prevent the lactation process, the drug is used in case of premature birth according to the following scheme: the first day - 3 tablets, the second and third - 2 tablets, from 4 to 7 days - 1 tablet.
Side effects
According to the reviews of Norkolut, some patients may develop unpleasant or painful effects associated with the side effect of the drug during drug therapy:
- nausea, heaviness in the stomach, vomiting;
- cephalgia;
- fatigue;
- allergic phenomena, manifested in the form of skin rashes and itching, swelling;
- a feeling of heaviness, engorgement of breast tissue;
- change in blood composition: when using the product, it acquires a tendency to increased coagulability.
With prolonged admission without specialist supervision, this can lead to vascular thrombosis and thromboembolism. In addition, an increase in bilirubin levels in the blood is possible. Weight gain (such a side effect of Norkolut is rarely observed, plus weight gain is most often insignificant). Bleeding due to the use of this medication is also quite rare, but patients are very worried. They can be of various intensities: from minor bloody spotting to heavy bleeding. The occurrence of such a side effect requires urgent consultation with a specialist.
It is important to familiarize yourself with the reviews about Norkolut with endometrium in advance.
Contraindications
The use of this pharmacological drug has some relative absolute contraindications.
Doctors refer to absolute contraindications:
- tumor processes in the mammary glands or reproductive organs of a malignant nature;
- puberty;
- allergic reactions to this medication.
The list of relative contraindications is much wider. If a woman has the following pathologies or conditions, Norkolut can be used, but with caution.
Relative contraindications are:
- the period of pregnancy (with the exception of cases when the medication is prescribed to prevent spontaneous miscarriage);
- acute or chronic liver diseases (including a history of hepatitis);
- high blood levels of bilirubin;
- a variety of bleeding unexplained causes;
- increased blood coagulation, thromboembolism, acute thrombophlebitis;
- severe renal pathology;
- epilepsy or other pathologies that are accompanied by the development of seizures;
- hypertonic disease;
- migraine;
- diabetes;
- bronchial asthma;
- obesity of the second and third degree.
Drug interaction
The simultaneous administration of the pharmacological drug Norkolut with such substances as rifampicin, phenytoin, cimetidine, barbiturates (phenobarbital) is contraindicated. This medicine should be used with caution in combination with the following medicines:
- steroid hormones;
- blood clotting drugs;
- drugs that lower blood sugar.
Norkolut and alcohol
This is not to say that this medication is categorically incompatible with alcohol, but their combination can lead to unpredictable negative consequences. If a woman cannot avoid drinking alcohol for any reason, she must take into account that at least three hours should elapse between taking the medication and the alcohol.
The unpredictable consequences of the simultaneous use of alcohol and taking the drug are possible mainly from the liver.
Analogs
Medicines similar in therapeutic effect or in composition to the Norkolut medicine are:
- "Orgametril";
- Primolut-Nor;
- Pregnin;
- "Progesterone";
- "Utrozhestan";
- "Postinor";
- "Provera";
- Lactinet
- “Depo-Provera”;
- Veraplex
- Eskinor-F;
- “Escape”;
- "Non-country".
Reviews about Norkolut
Reviews of women about this medicine are mostly positive. Women who took it were satisfied with the result, and not only in the treatment of diseases of the genital area, such as endometrial hyperplasia, endometriosis, etc., but during menopause in the body and before they start (after 40 years).
According to reviews of Norkolut with endometrial hyperplasia, the pathological symptoms that accompanied these disorders disappeared quickly while taking the drug, the menstrual cycle stabilized, which can be said about general health.
The medication, judging by the reviews, is well tolerated. Most women did not observe side effects, however, in some cases, minor symptoms of nausea and weakness were noted.