"Nazol Advance" is a combined medicine used to treat rhinitis in acute and chronic form in patients of adult and adolescence. It is an effective vasoconstrictor agent. It helps to restore nasal breathing and eliminate swelling of the mucous membranes. Its use is allowed if necessary, the symptomatic treatment of rhinitis accompanying acute respiratory viral infections, influenza, colds. The manufacturer produces the drug in two dosage forms - drops and spray, which helps to maximize the use of the drug and effectively deliver it to the inflamed mucosa.
Description of the drug
This tool is an anti-inflammatory combined medication to eliminate puffiness, which has a local mechanism of action. The main active ingredient in the "Nazol Advance" is oxymetazoline hydrochloride, having a concentration of 0.05%. This substance is characterized by a pronounced decongestant and vasoconstrictor effect. As a result, nasal breathing is released, swelling on the mucous membranes of the upper respiratory system disappears, especially in the nasal cavity. At the same time, the active substance is able to open the mouth of the Eustachian tubes and sinuses narrowed during rhinitis.
Additionally, under the influence of the drug, such an unpleasant symptom of rhinitis in acute form, such as stuffy ears, is eliminated. This effect is due to the ability of oxymetazoline to normalize pressure in the auditory tube.
In addition to the active substance, such auxiliary ingredients as purified water, sodium dihydrogen phosphate, benzyl alcohol, disodium edetate, propylene glycol, menthol, eucalyptol, camphor are used in the manufacture of the medicine.
Outwardly, “Nazol Advance” looks like a clear liquid with a light yellow tint and a characteristic eucalyptus-menthol aroma. Packed in bottles of polyethylene of 15, 30 ml. The bottle is placed in a cardboard box. Also available in spray form. In this case, the bottle is equipped with a special convenient spray.
The drug begins its effect 15 minutes after application, the maximum effect lasts up to 12 hours.
Recommendations for taking the drug
Before using the nasal spray, you must first clean the mucous membrane of the nasal cavity. This can be done by washing with a salt solution. When treating adolescents from 12 years of age, it is shown to produce twice a day up to 3 injections in each stroke of the nose. If there is an urgent need, the doctor may prescribe the use of the medication from 6 years. Children are shown to take 1 injection twice a day. Therapy with this tool takes up to 3 days. During the spraying process, the patient should not throw his head back to prevent the medicine from getting into his eyes. In cases where this does occur, rinse immediately with plenty of water. It is advisable to seek the advice of an ophthalmologist.
The Nazol Advance injection frequency determined by a specialist should not be exceeded, the duration of use and dosage should not be. The same applies to other vasoconstrictors, since such drugs can be addictive for a short period. As a result, such a widespread complication as rhinitis of drug etiology develops.
Pharmacological effects and drug group
According to its pharmacological group, “Nazol Advance” is an alpha-adrenostimulator intended for external use. The category of the drug is vasoconstrictor drugs. After the active components of the drug enter the nasal mucous membranes, a decongestant, antiseptic and anti-inflammatory effect quickly develops. Oxymetazoline hydrochloride is practically not absorbed into the blood, affecting tissues in the nasal cavity exclusively locally.
Very often, a nasal spray is used as a prophylactic against swelling of the mucous membrane in the nasal cavity before surgery, and it can also be used in preparation for a variety of instrumental studies, for example, rhinoscopy.
Such components of plant origin in the composition of the drug as camphor, eucalyptus oil and menthol act as a strong antiseptic, decongestant and anti-inflammatory agent. However, they contribute to liquefaction and rapid elimination of mucus from the nasal passages. It must be borne in mind that camphor and menthol, even if used locally, can partially penetrate the systemic circulation. Eucalyptol and camphor additionally have natural bactericidal and fungicidal properties. Thus, the use of "Nazol Advance" is effective in the treatment of colds of bacterial origin.
The combination of essential oils and propylene glycol allows you to soften and moisturize the mucous membrane affected by inflammation, however, it must be remembered that prolonged use of the drug causes the opposite effect - thinning of the mucous membrane and persistent drying out develop in the nasal cavity. What else does the instructions for use with Nazol Advance tell us?
Indications for the use of a medication
It is a drug with a complex effect. Its use is indicated in the following situations:
- Chronic nasopharyngitis.
- Sinusitis.
- Rhinitis in the chronic stage.
- Infections that affect the upper respiratory system and have an acute course.
- Sphenoiditis.
- Ethmoiditis.
- Frontite.
- Sinusitis
- Otitis in acute form.
- ARVI.
- Flu.
- Colds.
- Rhinitis of an allergic nature.
- Acute rhinitis of acute origin.
Along with other drugs that can narrow vessels in the nasal cavity, it is often prescribed as a prophylactic drug in preparing the patient for diagnostic procedures and surgical procedures in the nasopharyngeal cavity.
Contraindications to the use of the drug
According to the instructions for use with "Nazol Advance", it is not recommended to use the medication in the presence of physiological or pathological conditions such as:
- Severe form of hypertension.
- Glaucoma in a closed-angle form.
- Atrophic rhinitis.
- Hypertrophic changes in the prostate gland.
- Severely impaired liver function.
- Thyrotoxicosis.
- Atherosclerosis.
- Individual hypersensitivity to any substance that is part of the medication.
Cautious medication
Care must be taken when prescribing a nasal spray "Nazol Advance":
- Patients under the age of 12 years.
- In the presence of CCC diseases in a chronic form.
- With coronary heart disease.
- With heart failure.
- With any type of diabetes.
- In cases of impaired thyroid function.
- In the presence of pheochromocytosis.
- Persons using MAO inhibitors and tricyclic antidepressants on an ongoing basis.
Can a medicine be used during pregnancy?
Use "Nazol Advance" during pregnancy, even though it is a medication of local influence, is prohibited. Due to the probability of penetration of certain substances of the drug into breast milk, it should not be used in the lactation period.
If you need to use the drug in the lactation period, a woman needs to stop breastfeeding, and this should only be done if the intended benefit will be significantly higher than the likely risk.
The use of the drug in the treatment of children
The use of the drug for the treatment of rhinitis in children under 6 years of age is strictly prohibited. Most manufacturers of this medication in the instructions for use indicate that the drug can be used only from 12 years old. There is a special form of medication called "Nazol Baby", it is she who should be preferred in treating babies.
Negative effects of this drug
Against the background of the use of "Nazola Advance" negative reactions may develop, expressed in:
- Increased anxiety.
- Insomnia.
- Nausea.
- Tachycardia.
- Lightheadedness.
- Increased blood pressure.
- Burning in the nasal cavity.
- Dry mucous membranes in the nasal cavity.
If any of these symptoms occurs, you must stop using the product and seek the advice of a doctor.
Long-term use of the drug (for a month) can provoke the development of persistent drug dependence. As a result, this can cause a serious complication called atrophic rhinitis.
Analogs of Nazola Advance
If necessary, it can be replaced with one of the following drugs: Otrivin Oxy, Oxymetazoline, Oxyphrine, Nesopin, Afrin Estra, Moisturizing Afrin, Vix Active, Nazosprey, Nazivin Sensitive ”,“ Nazivin ”,“ Afrin ”,“ Nazol ”.
It is important to remember that each of these medicines has a number of specific contraindications and is able to provoke the development of various negative reactions. In this regard, the advisability of replacing the drug with another drug should be determined by the doctor.
Reviews for Nazol Advance
What do people think about this drug?
Most of the reviews found about the experience of using the drug are positive. Patients report an effective and rapid effect of the drug in the fight against nasal congestion. It is separately noted that the effect of the drug persists for a long period, in connection with which the medicine can be used only twice a day.
There are also negative responses associated with the fact that, against the background of the use of the medication, unpleasant negative effects arise in the form of burning and irritation of the mucous membranes, however, they disappear rather quickly and have a weak severity.
Despite the large number of positive recommendations, starting therapy with this drug should only be prescribed by a doctor. Otherwise, there is a likelihood of complications. The rest of the patients say that the medicine is coping with its purpose, it is worth buying if you have trouble breathing.