The drug "Nystatin" refers to antifungal agents. It is mainly used to treat infections such as yeast-like fungi - candida, as well as for the prevention of diseases caused by them. For example, candidiasis of various localization caused by suppression of the flora of the gastrointestinal tract during antibiotic treatment. Especially in the treatment of "Tetracycline", "Neomycin" and other drugs. For prophylactic purposes, Nystatin is also prescribed for immunocompromised patients.
The mode of action of this drug is the destruction of the cell membrane, getting into the cell and then its destruction from the inside. Candida needs some time to adapt to Nystatin. If the treatment is delayed, then the drug loses its effectiveness. Therefore, if Nystatin is prescribed for the treatment of a fungal disease or prophylaxis of the latter , the instructions for use are extremely important.
The form of release of the drug is different, since it acts directly on the area of candida active growth. "Nystatin" in the form of tablets or granules for dilution with water (for babies) is used to treat candidiasis in the gastrointestinal tract. In the form of vaginal suppository suppositories, the drug is used to prevent and treat vaginal candidiasis, which is popularly called thrush. Another form of release - rectal suppositories - is necessary for the treatment of colon candidiasis. And finally, the last form is Nystatin ointment. Its application is the treatment of skin areas affected by a fungus.
Such a variety of release forms is due to the fact that Nystatin is poorly absorbed in the gastrointestinal tract, as a result of which it cannot fight against fungi that affect the mucous membrane of the respiratory system, mouth, and vaginal fungal infections. It should not be taken uncontrollably, since it has a side effect. Diarrhea, abdominal pain, nausea and vomiting - these are the list of side effects that Nystatin can cause. Instructions for use determine the dose of the drug needed in the treatment of candidiasis and its prevention, and also clearly indicates in which case it is preferable to use certain forms of release of this drug.
In particular, the instructions indicate how much and for how long Nystatin should be used for various types of candidiasis. Rectal suppositories are used twice a day for 1-2. They are introduced into the anus after cleansing the rectum naturally or with an enema. The duration of treatment is 1.5-2 weeks. Vaginal suppositories "Nystatin" are introduced into the vagina in the same amount and over the same period of time. At the same time, the instructions stipulate that with simultaneous use with clotrimazole "Nystatin" reduces the effectiveness of this drug.
Tablets are taken orally. Depending on the severity of the disease, adults are prescribed 250 or 500 thousand units. active substance 3 or 4 times a day, for children under the age of 125 thousand units, from one to five years for 250 thousand units, children under 13 years old are invited to give the usual adult dose, but it is necessary to divide her to more receptions. In especially complex diseases, it is allowed to take up to 6000 thousand units.
Cases of allergic reactions to Nystatin are known. Instructions for use prohibit taking it to pregnant and lactating women, as well as all other patients in the presence of body sensitivity to this drug. Moreover, in recent years, a lot of other drugs have appeared that have successfully replaced Nystatin in the fight against fungal diseases, the spectrum of action of which is wider.
It is known that "Nystatin" is necessary for antibiotic treatment only in cases where the patient's body is weakened by a serious illness. For example, patients with HIV infection or cancer patients. In other cases, the human body is able to cope with fungal infections on its own, without the use of the drug "Nystatin". The instructions for use also indicate that the period of treatment with the drug should last at least 10-14 days, since if these terms are violated, there is a chance of developing resistant species of fungi that are not sensitive to it. In this case, the use of the drug must be stopped immediately.
It must be remembered that when using Nystatin or any other antifungal agent, it is recommended to combine them with the use of biologically active additives, which include various vitamin complexes. This will enable the immune system to cope with the disease much faster.