Dexketoprofen is a non-narcotic pain medication from a number of non-steroidal anti-inflammatory drugs. It is made from propionic acid. The medication is produced in the following forms: tablets, ointment and solution for intravenous and intramuscular administration.
The medicine in ampoules is a clear liquid, which consists of the main active ingredient - dexketoprofen trometamol. Pharmachologic effect:
- analgesic;
- anti-inflammatory;
- antipyretic.
Pharmacological properties
The spectrum of action of the active substance lies in the suppression of the activity of enzymes that are involved in the production of prostaglandins - components that increase pain. The composition of the drug begins its analgesic effect thirty minutes after use and holds it for eight hours. With intramuscular or intravenous administration, the highest concentration of the drug in the blood reaches ninety-nine percent.
When is the medication prescribed?
Indications for use:
- Pain sensations of any etiology.
- Bone pain.
- Toothache.
- Arthritis of various origins (damage to the joints, which is accompanied by their inflammation).
- Arthrosis (degenerative and dystrophic joint disease, which subsequently affects cartilage, pathological changes appear in the capsule, as well as the synovial membrane, ligamentous apparatus and adjacent bone structures).
- Osteoarthrosis (a common ailment in which joints undergo degenerative and dystrophic lesions).
- Osteochondrosis (damage to the spine, which is characterized by degenerative-dystrophic disorders of the intervertebral discs and tissues of the vertebrae).
Contraindications
It is not recommended to use the drug in the following conditions:
- Polyps in the nasal cavity.
- Asthma.
- Digestive disorders.
- Pregnancy
- Lactation
During therapy with this drug, nausea, exacerbation of gastritis and gastric ulcer are possible. The occurrence of severity in the right hypochondrium indicates negative processes in the liver.
Admission Rules
The tablet is taken with meals. In case of impaired functioning of the kidneys or liver, the drug begins to be taken with small doses. The maximum course of treatment should not exceed five days, the interval between drug use - eight hours.
Intramuscular injections are given for severe pain every twelve hours, for more than two days it is impossible to use an intramuscular solution.
Intravenous administration must be carried out for thirty minutes. The solution is diluted with sodium chloride, as well as glucose and lactate. It is important to maintain cleanliness and sterility, keep the medication in a dark place, avoiding the sun.
Dexketoprofen in the form of an ointment or gel has the trade name Dextanol. Apply liniment externally, treating the affected areas of the skin. The gel can be applied several times a day, but it is not recommended to use more than seven days.
Before using the medicine, you must carefully read the instructions. The medication has certain prohibitions and adverse reactions.
People who have heart problems should use the drug with extreme caution. In addition, you need to monitor blood pressure, as well as the level of cholesterol and glucose in the blood. It is not recommended to allow their increase: patients who suffer from diseases of the heart and blood vessels are at risk for stroke or myocardial infarction.
Interaction
With the simultaneous use of Dexketoprofen with other non-steroidal agents, the effect of the drug on the body will be greatly overestimated. When using the medication, a medical specialist should consider the following features:
- The medication can not be used in conjunction with anticoagulants that thin the blood, as the side reactions of both drugs are amplified.
- Do not prescribe "Dexketoprofen" with medicines that have lithium in their structure, because in such a situation, their blood level will increase, which will lead to poisoning of the body.
Analogs of Dexketoprofen
There are medicines with the same active ingredient, but differing in trade names. Analogs in ampoules:
- Dexalgin.
- "Flamadex".
- Ketodexal.
Analogues of Dexketoprofen in tablets:
- Ibuprofen
- Nurofen
- Faspik.
- Ketonal.
- "Artrum".
- Decafen.
- Sertofen.
- "Rotalfen."
- Ibuprom.
- "Orafen."
Reviews about Dexketoprofen and its generics are positive. Patients report an effective effect on inflammation and pain. But you should not rely on the statements of people, because each organism is individual, and what helped one patient can harm another. Before using the medicine, you need to undergo a medical examination.
Ibuprofen
Tablets belong to the therapeutic group of non-steroidal anti-inflammatory drugs. They have antipyretic and analgesic effects and are used to reduce the intensity of the corresponding signs in various pathologies.
According to the instructions for use with the Dexketoprofen analogue, it is known that after taking the tablet, the orally acting component is instantly and absolutely completely absorbed into the general bloodstream from the lumen of the small intestine. The maximum content in the blood of "Ibuprofen" reaches after two hours. It is almost evenly distributed throughout all body tissues.
Dexalgin
A medication is a medicine from the group of non-steroidal anti-inflammatory drugs, which has a pronounced analgesic, anti-inflammatory and antipyretic effect. Dexalgin is widely used in many areas of medicine.
According to reviews and instructions for the analogue of "Dexketoprofen" in ampoules, it is known that already ten to fifteen minutes after administration of the medicine, a person notes an improvement in the condition and subsidence of the pain syndrome. The duration of the pharmacological effect is from four to eight hours.
Flamadex
A solution for parenteral administration represents a therapeutic group of non-steroidal anti-inflammatory drugs. It is used to reduce the severity of inflammation and pain in various pathological processes.
The active substance of the solution for parenteral infusion of the drug is considered a chemical derivative of propionic acid. A decrease in the concentration of prostaglandins leads to a decrease in the severity of inflammatory manifestations, which include hyperemia, pain, swelling of the tissues.
According to the instructions, it is known that after parenteral administration of the drug, the active component is rapidly absorbed into the systemic circulation and evenly spreads through the tissues. It is metabolized in the liver with the formation of metabolites, which are excreted mainly with urine.
Ketodexal
The drug is an analogue of Dexketoprofen injections. The drug is in the form of a solution for intravenous administration. The medication has an antipyretic, analgesic and anti-inflammatory effect. By inhibiting the production of prostaglandins due to inhibition of cyclooxygenase, the mechanism of action of Ketodexal occurs.
After thirty minutes after use, the analgesic effect of the drug occurs, which lasts from four to six hours.
Opinions of doctors and patients
Medical experts in their reviews of Dexketoprofen and their analogues tell about the high effectiveness of drugs that instantly eliminate unpleasant symptoms and the disease itself.
Patients noted the rapid analgesic effect of Dexketoprofen, high efficiency with moderate pain, and low cost compared to generics.