"Midokalm" is a muscle relaxant that affects the structures that make up the nervous system. This is a modern drug designed to eliminate pain, which is a symptom of many diseases. The medicine is well perceived by the body, its use does not lead to the development of a sedative effect. The medication is available in the form of tablets and a solution for injection. "Midokalm", analogues are selected and prescribed by a doctor. The form of the drug and the required dose depend on the severity of the disease and general health.
Pharmacokinetics
As a result of penetration into the digestive tract, the active component of the drug is well absorbed by the body. Its metabolism is carried out in the kidneys and liver. Excretion of "Midokalm" is made in the form of metabolites that are found in urine.
Indications for use
"Midokalm" is often used in neurological practice. Its use is necessary in the following cases:
- Raynaud's disease and systemic diseases in which trophic ulcers form on the limbs;
- diseases manifested by spasticity of the muscles, their increased tone, for example, multiple sclerosis and processes affecting the pyramidal pathways of the spinal cord; this also includes disorders resulting from neuroinfection, myelopathy, stroke;
- muscle dystonia and spastic paralysis in children;
- diseases affecting the musculoskeletal system and leading to muscle contracture;
- post-traumatic events and other pathologies.
Contraindications
"Midokalm" (analogues are no exception) is contraindicated in case of high sensitivity to its components. The medicine in the form of tablets is not prescribed for children under one year of age; the drug in the form of injections is not administered to children under three months of age. The use of "Midokalm" is unacceptable in the presence of myasthenia gravis and myasthenic syndrome, the same applies to muscle hypotension, the reason for the development of which is not clear.
The medication is contraindicated in patients whose body responds to allergic reactions to tolperisone, lidocaine and other components. The effect of the drug on the body of pregnant women and breastfeeding patients has not been investigated, but there is the possibility of its use in the first trimester. Despite the fact that "Midokalm", analogues of the medicine are safe, they are used with caution during the period of gestation and breastfeeding. Typically, pills and injections are prescribed in cases where the benefits to the body of the expectant mother significantly exceed the risks to the fetus and newborn. During therapy, breastfeeding is stopped.
Drug use, dosage
Tablets
The drug of this form of release is taken when eating food, dividing the daily norm by 3 times and drinking it with a small amount of water (the tablet can be ground into powder). Adult patients are not recommended to exceed a dosage of 450 mg per day. Treatment begins gradually with a minimum dose of 50 mg. Observing the patient’s state of health, the dose is gradually adjusted to the amount that has the necessary therapeutic effect on the body. After the end of the first course of treatment, the doctor may decide on the appointment of a second course.
Injections
"Midokalm", analogues of "Midokalm" in ampoules are administered intravenously and intramuscularly. In the first case, the drug in a volume of 100 mg is administered at a time, in the second, the dose of 200 mg is divided into two.
The anti-inflammatory and analgesic effects of the drug are enhanced by niflumic acid, so during the treatment period there is a need for its use.
Treating children
As mentioned earlier, the minimum age of the child can be 3 months. Up to 7 years of age, a daily dose of more than 5 mg / kg of body weight cannot be administered into a child’s body. In this case, the daily norm should be divided into three doses. Children from 7 to 15 years old are given a dose of 2 to 4 mg per kilogram of body weight three times a day.
If necessary, the doctor will select an analogue. "Midokalm" - injections or tablets of drugs that are complete substitutes for the original drug.
Side effects
The medicine rarely causes unwanted reactions of the body. The highest risk of side effects is present in patients with hypersensitivity to the main component of Midokalm. Possible manifestations:
- headache;
- the appearance of nausea followed by vomiting;
- a feeling of weakness in the muscles and discomfort in the abdomen;
- skin reactions, swelling, anaphylaxis, other allergic reactions;
- low blood pressure with rapid administration of the drug.
Usually, a reduction in dosage leads to the elimination of the negative effects of treatment.
If the accepted dose exceeded the recommended, the patient may experience shortness of breath, choking, and cramping. Negative manifestations resulting from an overdose are easily eliminated by washing the stomach.
special instructions
The drug does not reduce attentiveness and speed of reactions, therefore, you can engage in any activity during treatment with the Medokalm medicine. Instructions for use analogues also allows you to accept when performing critical work.
Drug interaction
Since Midokalm, when combined with niflumic acid, enhances the effect it has on the body, the dose of this substance should be minimal.
The active component does not lead to the development of a sedative effect, therefore, the drug can be used with sleeping pills and sedatives, as well as together with medicines containing ethanol.
The effect of tolperisone is more pronounced with combined treatment with the use of "Clonidine", peripheral muscle relaxants and agents designed to provide general anesthesia.
Analog drugs: reviews, cost
More profitable than the Midokalm remedy. The price of substitutes is often lower. The cost of Midokalm tablets of 50 and 150 mg averages 250 and 300 rubles. accordingly, the price of ampoules is 370-515 rubles.
As analogues, mainly tolperisone hydrochloride, tolperisone and tolperil are mainly used. Their cost is about the same, the action is no less effective than that of Midokalm. These drugs, once in the body of a sick person, quickly lead to pain relief. In their composition there is the same active substance, which is included in the medication "Midokalm". Analogs may well be used as a substitute.
According to reviews, muscle relaxant helps fight the negative manifestations of a hernia of the intervertebral discs, especially in cases where non-steroidal drugs, whose action is aimed at relieving inflammation, do not eliminate the completely present pain. In such situations, combination treatment is the best option. You can study, before taking "Midokalm" reviews. Analogues are cheaper, but also give an effect. Although it is believed that the muscle relaxant "Midokalm" copes with the task in the best way. In some cases, the effect of its use can be seen after the first pill. This is a great treatment for sore joints. Reviews characterize the drug as one of the popular drugs to improve well-being in osteochondrosis (thoracic and cervical).