How to use the drug "Dizal"? Instructions for using this tool will be presented later. You will also learn about what components are part of the medication mentioned, in what form it is released, whether it can be prescribed to children and pregnant women.
Composition, form, description of the drug
What are the components of the drug "Dizal"? Allergy pills, the instruction of which is enclosed in a cardboard package, are blue, biconvex and round in shape, as well as the LT engraving on one side. The active substance of this medication is desloratadine. Also, its composition includes additional ingredients in the form of microcrystalline cellulose mannitol, pregelatinized corn starch, magnesium stearate and talc.
As for the film coating of the tablets, they include blue opadra, macrogol and indigo carmine dye.
It should be noted that the drug in question is available in the form of a syrup. Desloratadine is also its active substance.
Pharmacology
How does the Dizal medication (allergy pills) work? The instructions that came with this tool informs you that it is a long-acting antihistamine. It is a blocker of peripheral histamine H1 receptors.
The active substance of this medication is the primary active metabolite of loratadine. It inhibits allergic reactions, releasing pro-inflammatory cytokines and chemokines. This component also reduces the production of superoxide anions, chemotaxis and eosinophil adhesion.
This effect of the drug helps to prevent the development and alleviate allergic reactions. The drug in question has antiexudative and antipruritic properties, prevents the development of smooth muscle spasms, tissue edema and reduces capillary permeability.
Dizal pills, the price of which will be indicated below, does not have any effect on the central nervous system, nor does it have a sedative effect (that is, does not cause drowsiness) and does not affect a person's psychomotor reaction (when taking the recommended dosages). In addition, the medication in question does not extend the QT interval on the ECG.
The therapeutic effect of this drug begins within half an hour after ingestion and lasts throughout the day.
Pharmacokinetics
What pharmacokinetic parameters does the Dizal medication (allergy pills) have? The instruction reports that after taking the drug, its active substance is well absorbed from the digestive tract. In blood plasma, it is determined after half an hour, and its maximum concentration is reached after about three hours.
Communication with plasma proteins of the drug is 85-87%, and the half-life is about 28 hours. Desloratadine is excreted from the body through the intestines (less than 7%) and together with urine (less than 2%).
Indications for use
From an allergy to the face, this drug helps very well. It is used not only to alleviate, but also to eliminate the following symptoms:
- urticaria (rash and itching);
- allergic rhinitis (rhinorrhea, sneezing, itching of the palate, nasal congestion, redness and itching of the eyes, itching in the nose, lacrimation).
Contraindications
From allergies during pregnancy, the drug "Dizal" is prohibited. Also, it is not prescribed for breastfeeding and in children under 12 years of age (safety and effectiveness have not been established). Do not use this medication and with increased sensitivity of the patient to an active or any additional ingredient of the drug.
With extreme caution, Dizal tablets are prescribed for severe renal failure.
The drug "Dizal" (tablets for allergies): instructions
Only a narrow specialist should prescribe such tablets. Allergies (urticaria, itching, rash, etc.) in children from 12 years old and adult patients are eliminated equally. According to the instructions, the tablets must be taken orally, regardless of the meal. The dosage of this medication is determined by the doctor and, as a rule, it is 5 mg once a day (that is, 1 tablet per day).
Adverse reactions
From allergies for children over 12 years of age, the drug "Dizal" should be prescribed with extreme caution. This is due to the fact that this medication can cause a large number of side effects.
More often than others, patients experience adverse reactions such as increased fatigue, persistent headaches, and dry mouth.
During the observations, other side effects were also identified. Imagine them right now:
- From the nervous system, drowsiness, psychomotor hyperactivity, dizziness, and insomnia may be noted.
- From the digestive tract, abdominal pain, diarrhea, nausea, dyspepsia and vomiting are observed.
- On the part of the biliary tract and liver, phenomena such as an increase in the concentration of bilirubin, an increase in the activity of liver enzymes and hepatitis occur.
- From the side of the heart and blood vessels of patients, tachycardia and a feeling of palpitations are disturbing.
- From the bone and muscle system, myalgia is observed.
It should also be noted that while taking the drug in question, patients may experience mental disorders in the form of hallucinations and allergic reactions in the form of itching, anaphylaxis, rash, angioedema, and urticaria.
Overdose Signs
From allergies for children over 12 years of age, as well as for adults, the drug “Dizal” should be taken at the dosages recommended by the doctor.
When taking medication in high doses (for example, 9 times, which is 45 mg), no clinically significant signs occur. However, drowsiness may develop.
As a treatment, you need to rinse your stomach and take activated charcoal. It should also be noted that desloratadine is not excreted by hemodialysis.
Other drug compatibility
The interaction of the drug "Dizal" with other medications was not detected (including with "Erythromycin" and "Ketoconazole"). It should also be said that desloratadine does not enhance the effect of ethanol on the central nervous system.
Special recommendations
Allergies (urticaria, itching, rash, etc.) in people with severe renal impairment should be treated with extreme caution.
According to studies, the drug "Dizal" does not affect the driving of the patient in any way. But it should be borne in mind that it is extremely rare for some people to develop drowsiness. In this case, special care must be taken when driving and when working with complex mechanisms.
Cost and drug analogues
Unlike other antiallergic drugs, the price of the drug "Dizal" is not very high. You can buy this medication for 200-350 rubles (10 and 30 tablets, respectively).
As for the analogues of the medication in question, there are a great many of them. We list them: Lordestine, Blogir-3, Erius, Desloratadine, Elyseus, Desloratadin-Teva, Ezlor, Desloratadin Canon, Nalorius, Desloratadine-Pharmaplant.
Reviews about the antiallergic drug
The drug "Dizal" is an inexpensive drug against allergies, which leave a lot of negative and positive reviews. Most patients report that this medication copes well with the task. It quickly and effectively eliminates all the symptoms of an allergic reaction, significantly improving the well-being of the patient.
People who took Dizal tablets show that it’s very convenient to use them. Unlike other drugs, the medication in question is enough to take once a day and you can forget about allergies.
There are negative reviews about this medication. Many patients cannot take it, since they immediately show allergic reactions. Doctors prescribe safer drugs for such patients.