The drug called "Acetylsalicylic acid" is
an ordinary
aspirin , widely known around the world and actively used as an effective antipyretic, anti-inflammatory and analgesic. This medicine belongs to the pharmacotherapeutic group of non-steroidal antiflogistic medicines.
Description of the pharmacokinetics of the drug
The basis of this tool is the inactivation of cyclooxygenase, resulting in a decrease in the production of so-called inflammatory mediators: thromboxane, prostacyclins and prostaglandins. In turn, a decrease in the synthesis of these substances leads to a decrease in their effect on thermoregulation centers and, as a consequence, to a decrease in body temperature. In addition, this drug significantly reduces the sensitizing effect of inflammatory mediators on nerve endings, as a result of which the sensitivity of the latter to pain mediators decreases.
Area of use
Tablets "Acetylsalicylic acid", the instruction recommends taking mainly with rheumatoid arthritis, rheumatism or myocarditis of an infectious-allergic type. This medicine also helps very well with myalgia and neuralgia. In addition, the drug "Acetylsalicylic acid" is aspirin, which is indicated for use in fever provoked by an infectious and inflammatory disease. Among other things, it is extremely effective to use it as a prophylaxis of myocardial infarction, the development of embolism and thrombosis, as well as the prevention of disorders in the cerebral circulation according to the so-called ischemic type. To eliminate severe pain of moderate and low intensity of various origins (including toothache or headache), it is similarly worthwhile to use the drug, referred to today as "Acetylsalicylic acid." The price of this drug is about ten to twelve rubles, and it is currently possible to purchase it at any pharmacy.
List of contraindications
Doctors do not recommend using this medicine to people with erosive and ulcerative lesions of the gastrointestinal tract, hemophilia, portal hypertension or hypoprothrombinemia. In addition, “Acetylsalicylic acid” tablets are aspirin that should not be taken in case of an established “aspirin triad”, exfoliating aortic aneurysms, hemorrhagic diathesis, vitamin K deficiency and Reye syndrome. Also, gastrointestinal bleeding, rhinitis provoked by the use of non-steroidal anti-inflammatory drugs, renal or liver failure are direct contraindications. Patients under the age of fifteen, women who have a baby, and young mothers who are breastfeeding, similarly should not take this medicine. Finally, the preparation “Acetylsalicylic acid” is aspirin, which should not be used categorically in case of increased individual sensitivity of the body to acetylsalicylic acid and other salicylate substances.