In the article, we consider the Vermox preparation, instructions for use, reviews and analogues.
The drug belongs to the pharmacological group of anthelmintic drugs. The main active element is mebendazole, which leads to the death of various types of helminths, therefore this medication is used for the etiotropic treatment of helminth infections in adults and children. In addition, the drug is most effective against pathogens of enterobiosis and trichocephalosis. According to the instructions for use, Vermox can be used for prophylaxis in adults and children.
It is an anthelmintic drug that has a wide range of effects. High efficiency is noted in diseases such as enterobiasis, ascariasis and trichocephalosis. It primarily affects the energy processes in parasite cells, causes a violation of the synthesis of glucose and ATP, and depletes glycogen stores. Selectively able to inhibit the synthesis of β-tubulin in helminth cells, which contributes to their paralysis and disruption of the functioning of transport systems.
The drug has a detrimental effect on the hookworm and roundworm larvae. In high dosages, it is used to treat echinococcosis and trichinosis - extraintestinal helminthiases.
What else does the instruction manual for Vermox tell us?
Composition and release forms
The medication is made exclusively in tablet form. The tablets are white and rounded in shape. The main active substance is contained in each of them in an amount of 100 mg. The composition of the tablet also includes some auxiliary components, the list of which includes:
- colloidal silicon dioxide;
- sodium lauryl sulfate;
- magnesium stearate;
- sodium saccharinate;
- corn starch;
- talc;
- lactose monohydrate.
Vermoxum tablets are packaged in special blisters of 3 each. A cardboard pack contains two blisters and instructions for the use of the medication.
Pharmacological effects
As indicated by the instructions for use with Vermox, the main active substance of this drug is mebendazole, which selectively blocks the synthesis of intracellular helminth protein - tubulin, which contributes to disruption of the processes of adsorption and absorption of nutrients (including glucose) and the development of energy starvation, followed by the death of helminth and its removal from the intestine.
In addition, mebendazole inhibits the synthesis of adenosine triphosphoric acid molecules - the main energy storage cell of helminth cells, which further exacerbates their energy hunger. The main active substance of these tablets has a wide effect on most helminths. The maximum activity of the drug is manifested in the destruction of helminths - pathogens of ascariasis and trichocephalosis.
After taking the tablet orally, mebendazole begins to be absorbed into the blood in small quantities, where it binds to plasma proteins and undergoes a metabolic process in the liver to breakdown products. The main part of the main substance is excreted through the intestines with feces, and only a small part - about 10% - through the kidneys, with urine.
Indications for use
In accordance with the instructions for use with Vermox, this pharmacological preparation is indicated for the treatment of certain parasitic diseases that can be triggered by certain types of helminths. The list of such pathologies includes:
- Ascaridosis, which is a parasitization in the intestines of helminths such as roundworms, belonging to the class of roundworms.
- Trichocephalosis - intestinal helminthiasis, also caused by some representatives of roundworms.
- Enterobiosis is a parasitic disease caused by pinworms, which also belong to the category of roundworms and parasitize, as a rule, in the lower regions of the intestine, most often in children.
- Trichinosis, which is caused by helminths belonging to the class of nematodes, it is characterized by the habitat of their larvae in internal organs and muscles.
- Ankylostomidosis is a parasitic pathology caused by an intestinal parasite, which is mainly localized in the duodenum and belongs to the group of roundworms. The disease often leads to acute forms of anemia.
- Cysticercosis and teniosis, which are parasitism of pork tapeworm in the intestine, which may be in the larval stage or in the form of an adult.
- Alveococcosis is a helminthiasis caused by larvae of flatworms, which parasitize mainly in the liver.
- Capillary disease, which is a pathology caused by small capillary helminths.
- Echinococcosis is a pathology that has some similarities with alveococcosis, but it most often affects the lungs and liver.
- Gnatostomiasis, which is a parasitism of helminths from the category of nematodes, the action of which leads to the formation of specific nodules in the skin.
In addition, the use of the drug in tablets is indicated for the mixed form of helminthiasis caused by several parasites at the same time. Instructions for use with Vermox are very detailed.
List of contraindications
The use of a medication is contraindicated in a number of physiological and pathological conditions, which include the following:
- intolerance or increased susceptibility by the body to mebendazole or other components of the drug;
- children's age up to two years;
- Crohn's disease, which is a non-specific inflammatory process in the colon of a chronic form;
- ulcerative colitis - inflammation of the mucous membranes of the colon of a chronic nature with the formation of erosion and ulcers.
- liver failure of any form;
- period of pregnancy at any time and breastfeeding.
Before you start using the product, you need to make sure that there are no contraindications and get a specialist appointment. Especially if you decide to give Vermox according to the instructions for use for prophylaxis for children.
Dosage and route of administration
The drug "Vermox" is taken orally, the tablet should be swallowed in its entirety, without chewing it, and washed down with a small amount of liquid. Dosages depend on the age and type of helminth, which provoked the development of a particular pathology:
- Adults and children after two years with enterobiasis are prescribed 100 mg per day, with mixed helminthiasis - 100 mg 2 times a day. The duration of treatment is three days. In cases of persisting symptoms of helminthiasis, the course of therapy should be repeated after three weeks.
- For children over 14 years old and adults with mixed helminthiasis and enterobiasis, the dosage and pattern of use of the drug is the same. With echinococcosis, it is significantly higher and amounts to 500 mg (2 times a day for 3 days, after which 500 mg for 3 days). Subsequently, if necessary, the dose can be increased to 1000-1500 mg. Therapy is from 4 to 6 weeks.
- With trichinosis, the drug is taken as follows: on the first day - 300 mg 3 times a day, on the second day - 300 mg 4 times a day, and from the third day - 500 mg 3 times a day. The course should be at least two weeks.
- In case of teniosis, trichocephalosis and ascariasis, the recommended regimen is 100 mg 2 times a day.
In addition, it is also recommended that the prophylactic use of the drug be carried out to all family members who are at risk of infection with one or another type of helminthiasis.
Adverse reactions
According to the instructions for use and reviews of "Vermox", after taking the drug, certain side effects may occur in the form of dyspepsia, headache, pain in the abdomen. Also, the development of allergic reactions in the form of rashes on the body, its itching or urticaria is sometimes observed.
During therapy with high doses of this drug, some liver disorders may develop, which indicate the destruction of hepatocytes (increased levels of liver transaminase enzymes). A long course of treatment with this medication is the cause of the development of leukopenia (a decrease in the number of white blood cells in the blood). In case of adverse reactions, the use of this medication is recommended to stop and consult a specialist.
This is confirmed by the instructions for use for Vermox for adults and children.
special instructions
Before using the medicine, it is very important to carefully read the information contained in its instructions. There are some specific instructions regarding the use of this medication, which include:
- While taking pills in patients with insulin-dependent diabetes mellitus, the need for insulin decreases, which must be taken into account to prevent the occurrence of hypoglycemia (a significant decrease in blood sugar).
- During prolonged use of the Vermox medication, regular laboratory monitoring of the functionality of the kidneys, liver and red bone marrow is necessary.
- After the end of the therapeutic course, it is necessary to conduct a laboratory assessment of its effectiveness (analysis of feces for the presence of helminth eggs in it or other studies).
- During treatment with this medicine, alcohol should be excluded.
- It is not recommended that you take Vermox at the same time with drugs with the ability to accumulate in adipose tissue.
- Special recommendations on diet or the use of laxative medications during treatment are not required.
- A pharmacological drug does not affect the degree of concentration of attention and the speed of mental reactions.
This is stated in the instructions for use for Vermox.
Analogues of the drug
Analogs for therapeutic effects for the medication are:
- Mebendazole
- Albenzene
- "Fed";
- "Pirantel";
- "Phytoglistericide";
- Dekaris;
- Zentel;
- "Nemozol";
- Medimin;
- Klinlife;
- "Parasitget";
- Stopgelmint;
- "Lamb";
- Salviton;
- "Antiparasit";
- Ecorsol.
Consider the instructions for use for Vermox for children.
Use of the drug in children
It is known that children often suffer from diseases such as helminth infections. However, to get rid of parasites in the child's body, the use of effective anthelmintic drugs is necessary. One of such tools is Vermox, however, it can only be used in children over two years of age. This is due to the fact that in the first two years of life it is extremely dangerous to use this medication because of the likelihood of seizures in the child. Nevertheless, it is possible to use this medication in such an age group if the specialist has identified a serious helminth pathology that interferes with the digestion and physical development of the child. In this case, the treatment regimen and dosage are determined strictly individually.
As indicated by the instructions for use for Vermox for children, it is not recommended to use this drug in the following cases:
- With hypersensitivity in a child to mebendazole or other components of tablets, for example, to lactose.
- Children with Crohn's disease and ulcerative colitis of a non-specific nature, since a medication can help clog the intestinal lumen with helminths, which will seriously worsen the condition.
- Children with liver failure, as this drug has the ability to destroy organ cells. Especially if you give the product just for prevention.
Instructions for use with Vermox also describe this in detail.
Drug Reviews
Tablets are relatively recent in the pharmaceutical market, however, they have proven themselves in the best way. This is evidenced not only by the numerous reviews of patients who were prescribed this medication for the treatment of various types of helminthiasis, but also by the doctors themselves, who today most often prescribe Vermox.
Patients note the high effectiveness of the drug for ascariasis, enterobiosis, echinococcosis and other helminth pathologies. Many of them observed the disappearance of the main symptoms of the disease after the first days of using this medication, which, in their opinion, is considered a significant advantage compared to other means. Some of the patients who were diagnosed with severe forms of helminthiases, this effect was observed somewhat later, in particular, at the end of a two-week course of therapy.
It is better to familiarize yourself with the instructions for use of Vermox (100 mg) in advance.
The use of the drug in children is also reflected in consumer reviews, many of which use this drug to prevent parasitic pathologies. Parents are pleased with the drug, however, they note that children often experienced some adverse reactions after taking the pill, such as nausea and headaches, which negatively affected the mood and general well-being of the babies. However, after conducting a laboratory assessment of the effectiveness of the treatment, the parents note that, judging by the analyzes, no helminths were found in the feces of the children.
We reviewed the instructions for use with Vermox tablets.