"Suprax": reviews, indications, instructions for use, release form, analogues

"Suprax" represents a pharmacological group of drugs called antibiotics third-generation cephalosporins. It is used to treat infectious and inflammatory pathologies of various localization caused by infectious agents sensitive to the main component of a medical device. Consider how to take Suprax.

Also, the article will give a detailed description of the drug, its medicinal properties, contraindications, side effects are indicated. Based on the instructions for use and on reviews of Suprax, we will analyze how children are treated with it.

Dosage form and content of the drug

For children, Suprax is available in the form of granules for the preparation of a suspension. It is intended for oral use. Granules are small, cream or white. Syrup "Suprax" has the same color and a pronounced smell of strawberries.

The main active ingredient of this pharmacological agent is a special micronized cefixime, the content of which in 5 ml of the prepared suspension is 100 mg. In addition, the composition of the drug granules includes some additional elements, which include:

• Xanthan gum.
• Sodium benzoate.
• Strawberry flavoring.
• Sucrose.

The drug granules of this medication are contained in dark glass vials in an amount of 30 g. The vials are packed in cardboard boxes. How to breed "Supraks"? A special dispensing spoon and instructions for using the medicine are attached to the medicine.

For adults, Suprax is available in white capsules. Each contains 400 mg of active substance.

Therapeutic effect, pharmacokinetics

Antibiotic Supraks for children and adults has an effect on the body, which leads to the death of microorganisms that are sensitive to the active substance of a medicinal product. Cefixime is a third-generation cephalosporin antibiotic class. The destruction of bacteria is due to the fact that this substance inhibits (inhibits) the synthesis of cell walls. Cephalosporins, unlike unprotected penicillins, are highly resistant to the damaging effects of beta-lactamase enzymes produced by certain types of pathogenic bacteria. As a result, the Supraks drug has an extensive spectrum of effects, is active against the largest number of different gram-positive (staphylococcus, streptococcus) and gram-negative (E. coli, Klebsiella, Pseudomonas aeruginosa, Proteus, Neisseria meningitis) bacteria.

After taking the drug, cefixime is relatively quickly and almost completely absorbed into the general bloodstream from the intestine and distributed in tissue cells, and also accumulates in areas of localization of inflammatory processes. The active component of the drug is excreted by the kidneys (unchanged in the urine).

Indications for use

The use of Supraks syrup for children is indicated for etiotropic therapy of infectious and inflammatory pathologies that are provoked by bacteria sensitive to the main substance of the drug:

1. Tonsillitis (inflammation of the tonsils), pharyngitis (inflammation of the nasopharynx) and sinusitis (inflammation in the paranasal sinuses).
2. Infectious pathologies of the lower respiratory tract, chronic or acute (otitis media).
3. Infectious processes with an uncomplicated course, localized in the organs of the urinary system (cystitis, urethritis).
4. Inflammatory processes of the middle ear, characterized by acute course (otitis media).

Contraindications

There are several physiological and pathological features of the child’s body, in which the use of Suprax suspension for children is excluded. These include:

1. High sensitivity or cases of individual intolerance to certain antibacterial drugs belonging to the representatives of the group of cephalosporins or penicillins.
2. A variety of impaired renal function.

With caution, this antibacterial agent is used to treat children with moderate renal failure, as well as with suspected pseudomembranous colitis. Before using a pharmacological preparation, a specialist must make sure that the child does not have contraindications.

Consider how to breed Suprax.

Dosage and administration

The drug granules are intended for the manufacture of a suspension that is taken orally. To do this, shake the bottle with the drug, pour 40 ml of medium temperature water into it, shake it thoroughly and let it brew for about five minutes to completely dissolve the elements. Before using this suspension, it must be re-shaken.

The total therapeutic dosage of Suprax for children depends on the age of the child:

• Children aged 5-11 years are prescribed 6-10 ml of medication (120-200 mg).
• Children aged 2-4 years - 5 ml (100 mg).
• Children aged 6 months to 1 year - 2.5-4 ml of the drug (50-70 mg).
• The dosage of Suprax for children under the age of 6 months is calculated on the basis of a dose of 8 mg per 1 kg of weight once a day or 4 mg per 1 kg of weight 2 times a day at regular intervals.

The total duration of the therapeutic course with this antibiotic for children varies between 7-10 days.

Adults and children over 12 years of age, whose body weight is more than 50 kg, the daily dose will be 400 mg (once or 200 mg 2 times / day). The course of treatment also lasts from 7 to 10 days. For uncomplicated gonorrhea, 400 mg is prescribed.

Adverse reactions

According to reviews of Supraks, against the background of the use of a drug in the form of a suspension made from granules, children may experience some negative reactions from different systems and organs:

1. Digestive system - loss of appetite (anorexia), severe dry mouth, nausea, which may be accompanied by periodic bouts of vomiting, stool instability (diarrhea or constipation), periodic abdominal pain. The onset of signs of dysbiosis (a pathological change in the state of normal microflora in the intestine), jaundice, bloating (flatulence), inflammation of the oral mucosa, glossitis (inflammation of the tongue), pseudomembranous colitis (a specific lesion of the internal membrane of the large intestine), impaired liver function.
2. Nervous system - severe cephalalgia, periodic dizziness, cramps, the appearance of noise in the head.
3. Urinary system - impaired renal function, acute renal failure, interstitial nephritis.
4. Red bone marrow and blood - a violation of hematopoiesis, the result of which is aplastic or hypoplastic anemia, an increase in the death rate of red blood cells, which is the cause of hemolytic anemia, bleeding from capillary vessels, leukopenia (a decrease in the number of leukocytes), neutropenia (neutrophils), agranulocytosis (granulocytes) or all blood cells at the same time (pancytopenia).
5. Allergic manifestations - skin rashes, itching, hives, severe swelling of soft tissues localized in the genital area, as well as the face (Quincke's edema), necrotic skin lesions (Stevens-Johnson syndrome), systemic reactions with a critical decrease in blood pressure levels and insufficiency internal organs.
6. According to laboratory indicators - an increase in the activity of alkaline phosphatase and hepatic transaminases, which indicates damage to liver cells (hepatocytes). This is confirmed by the instructions to the Suprax.

If symptoms of pathological reactions occur, the need to stop treatment with a medication is determined only by a doctor. You do not need to stop taking the drug yourself.

What is the compatibility of Suprax with alcohol? It is better not to take them together, as this will lead to severe intoxication of the body. It may be accompanied by nausea, vomiting, loss of consciousness, headache.

During pregnancy and lactation

You can use the medication during pregnancy only when the benefit to the mother is greater than the potential risk to the fetus. If it is necessary to use Suprax for lactation, breast-feeding is stopped.

special instructions

Before prescribing the Suprax antibiotic for children and adults, the doctor must pay attention to special instructions regarding its use. These include:

1. With prolonged treatment with this medication, the normal microflora in the intestine may be disrupted, which will lead to the development of dysbiosis. Therefore, after antibiotic therapy, the appointment of eubiotics or probiotics (agents containing live microorganisms for normal microflora) is recommended.
2. During the therapeutic course with this medication, false-positive results of laboratory tests of urine for glucose levels and the Coombs reaction are possible.
3. In children prone to penicillin allergies, a cross-allergic reaction may occur in response to cephalosporins.
4. The active components of the granules of the Supraks medication can interact with medicines of other pharmacological categories (carbamazepime, diuretics, allopurinol, indirect anticoagulants), therefore a pediatrician should be warned about their use.
5. The composition of this medicine includes sucrose, which should be taken into account when treating children with diabetes.

What else does the instruction for Suprax tell us?

Overdose symptoms

In children, an overdose of granules for suspensions may be accompanied by the occurrence or intensification of pathological side effects from the digestive system. In this case, it is recommended that the child wash the stomach and prescribe intestinal sorbents (for example, activated charcoal). Symptomatic therapy is also prescribed.

Analogs of "Suprax" for children

The following medicines are related to analogues of this medication:

1. Ceforal is a medicine based on the same active substance as Suprax. This drug is indicated for pharyngitis, bronchitis, otitis media, pneumonia and other diseases in children. Do not use the medication for asthma, kidney pathologies.
2. Amoxicillin is a Russian-made medicine, an analogue to Suprax granules. The basis is the drug of the same name amoxicillin. It is prescribed for children with infection of the respiratory tract, digestive tract, sepsis, purulent skin lesions.
3. Amosin is an antibacterial drug of domestic production based on amoxicillin. It is used for a variety of infectious and inflammatory pathologies of the respiratory and ENT organs, digestive system, otitis media, inflammation of the bronchi, meningitis and other pathologies. An analogue of Suprax for children should be selected by a doctor.
4. "Cephalexin" is a medicinal product of production in Serbia. The basis of this medication is the active substance cephalexin. It is prescribed for children with otitis media, bronchitis, pneumonia, skin infections, urinary tract infections.
5. "Iksim Lupine" - Indian antibacterial agent. The active substance in it is cefixime. This medication treats the above diseases of an infectious and inflammatory nature.
6. "Erythromycin" is a Russian antibiotic used for pathologies of the respiratory organs in children, the urinary system, etc. The active substance in it is erythromycin.

Reviews

This drug is often prescribed by doctors to treat various bacterial infections. Opinions of parents about the drug are very mixed. This can be concluded from the fact that the reviews about Suprax reflect both positive and negative information.

Many parents are very happy with this medicine. They claim that after the start of its use in children, there was a significant improvement in the general condition, a decrease or complete disappearance of some specific symptoms of the disease. Parents say granules are an excellent remedy for bronchitis, sore throat in children, and pneumonia.

Negative reviews of Suprax mainly describe the poor tolerance of this drug by children. Due to the high toxicity of the drug to the liver, numerous adverse reactions of the body were noted in the babies, which include vomiting, diarrhea, pain in the abdomen and others. In addition, in many cases, this antibiotic provoked the development of dysbiosis in children, which was manifested by diarrhea.

The opinion of experts is almost unambiguous. Most of them note that the Suprax drug at the current moment in the development of clinical medicine is one of the most effective medications that are advisable to prescribe to children, from a very early age, with a moderate and severe course of various inflammatory infectious pathologies. However, according to doctors, this medication has a number of significant contraindications, which must be very carefully read before prescribing a medication to a child.

Since the adverse reactions caused by taking Suprax can be significant, the medicine is most often prescribed for older children than infants, for whom it is advisable to choose a more gentle antibiotic. The effect of Suprax suspension for children on the functioning of certain organs and systems, according to pediatricians, is very large. It is associated with certain health risks, so using the medication on your own is strictly not recommended. Doctors indicate that parents must fully comply with all prescriptions and dosages prescribed by a specialist.

For adults, the drug is also well suited. It rarely causes side effects, but it is important to follow the instructions for use of the drug.

We looked at how to take Suprax.