Ketonal injections are a colorless or yellowish transparent solution. The active substance of the drug is ketoprofen. The drug belongs to the category of NSAIDs. The Ketonal agent (injections) is administered intramuscularly or into a vein (under stationary conditions).
Pharmacodynamics and pharmacokinetics
The solution has an anti-inflammatory, antipyretic effect and has an analgesic effect. The active component of the drug does not affect the condition of the cartilage of the joints. The bioavailability of the drug is more than 90%. With parenteral administration, the maximum content is reached after 15-30 minutes. The drug is found in synovial fluid. Metabolism passes in the liver. Most are excreted in the urine. About 10% - through the intestines.
Appointment
Ketonal injections are recommended for different types of arthritis: psoriatic, reactive, rheumatoid. The remedy is indicated for pseudogout, osteoarthrosis, radiculitis. A medication is prescribed for pain of a different nature (including oncology), myalgia, bursitis, tendonitis. A medication is recommended for gout, ankylosing spondylitis, neuralgia. Indications also include postoperative and post-traumatic pain syndromes, algodismenorea.
In what cases is the drug not prescribed?
Ketonal injections are not recommended for severe liver and kidney deficiency, hemophilia, and other blood clotting disorders. Medication for Crohn's disease, hypersensitivity is contraindicated. Not prescribed for patients under 15 years of age, lactating and pregnant. The drug is not recommended for heart failure of an uncompensated type, in the recovery period after shunting. Contraindications include chronic dyspepsia, bleeding of a different nature (cerebrovascular, gastrointestinal and others).
The drug "Ketonal" (injections). Instruction Price
Parenteral administration may be combined with oral administration. In the muscle, 100 mg is recommended 1-2 times a day. The cost of the drug is from 100 rubles.
Side effects
Ketonal injections can cause allergic reactions. Their most common manifestations are rashes, irritation, and redness of the skin. During therapy, gastrointestinal disorders, stomatitis, vomiting, increased or decreased appetite are likely. Often the drug causes headache, fatigue, nightmares. Some patients may experience nervousness, hallucinations, and speech impairment. In some cases, conjunctivitis, increased pressure, peripheral edema are observed . Rarely, interstitial nephritis develops , renal activity is impaired, hematuria occurs.
special instructions
Against the background of prolonged use, it is necessary to ensure control of the state of the blood picture, kidney and liver functions. This is especially important in the treatment of elderly patients. Like other NSAIDs, the Ketonal drug may mask signs of an infection. When prescribing the drug, people with hypertension should often check blood pressure.