Some antibiotics are available in the form of a lyophilisate (powder). They are intended for parenteral administration. The powder may have a dark or light color, in the first case, this may indicate both unsuitability and suitability for use of the drug. When dissolved, some drugs form a cloudy suspension or emit gas. Dilution of antibiotics is carried out in the volume indicated in the annotation. Instructions for use also contain information about the solution that is optimal for a particular drug.
Calculation and breeding of antibiotics
The determination of the number of milliliters of solvent for the drug is determined by dividing units or grams by 200 thousand (0.2) or 100 thousand (0.1), respectively. A 1: 1 dilution of antibiotics suggests that 1/10 gram of agent is contained in a milliliter of dissolved drug. So dilute the medicine in bottles containing 500,000 units (1/2 g.) Or less. Dilution of antibiotics can be carried out in a different proportion. This method is used for preparations contained in the amount of 500,000 or more units. In these cases, the drugs are dissolved in a ratio of 1: 2. This means that in a milliliter of the dissolved mixture there are 200 thousand units (0.2 g) of the drug.
How is antibiotic dilution carried out?
Before dissolving the drug, you must once again carefully read the annotation, the doctor’s prescription, and check the prescribed dose. You should also choose the place where the dissolution will be performed. A small table (or a section of the kitchen table) is covered with a clean napkin, where they put everything they need. It is necessary to prepare alcohol, cotton wool. The use of lotions or colognes is not recommended. The foil is removed from the medicine vial so that the center of the rubber stopper opens. In the case when the solvent is contained in ampoules, a special opening knife should be prepared (if necessary) (it is usually attached to the package). The packaging is removed from the disposable syringe; it is undesirable to remove the cap from the needle. Next, you need to wash your hands with soap and rub them with a solution of alcohol. The ampoule and rubber stopper of the bottle are also processed. After that, open the container with the solvent, fill in the required amount into the syringe. Next, the liquid is introduced into the bottle with the medicine, the needle is pulled out, the resulting mixture is shaken. The powder should completely dissolve. After they take another syringe and inject it into a vial with a dissolved medication. The needle should be completely immersed in the drug. The entire volume of the drug is collected, the injection site is rubbed with alcohol. As a rule, antibiotics are administered deeply and slowly into the muscle.
Which solvent should I choose?
Usually, when prescribing a medicine, a specialist recommends which liquid should be used. If there are no prescriptions from a doctor, then you can consult a pharmacist when buying a medication. In addition, the annotation contains all the necessary information. For dilution, different solutions can be used, for example, Lidocaine, Novocaine and others.