About many drugs produced by modern industry, there are very good reviews. "Tserukal" - an antiemetic drug of central action - is one of them.
The principle of the drug
The main substance that is part of the drug “Cerucal” is metoclopramide hydrochloride. The liquid preparation "Cerucal" in addition to metoclopramide contains disodium edetate, sodium chloride and sodium sulfite, as well as water. The composition of the tablets also includes lactose monohydrate, gelatin, potato starch and magnesium stearate. Judging by what reviews exist about him, “Cerucal” very gently relieves the vomiting symptom and normalizes the work of the stomach and intestines. The principle of action of this medicine is based on the ability of metoclopramide to block serotonin and dopamine receptors. As a result, there is a decrease in the sensitivity of brain nerve cells responsible for the transmission of impulses from the vomiting center of the duodenum located in the medulla oblongata.
Among other things, the drug “Cerucal” restores the motility of the upper gastrointestinal tract and normalizes the tone of the walls of the stomach and intestines. In addition, this medicine is able to prevent the development of a disease such as cholestatic jaundice. Its use allows you to eliminate the symptoms of gallbladder dyskinesia. In addition, the medicine “Cerucal” can contribute to the separation of bile.
In what forms is produced
Enteric-coated tablets are available in white. In addition, there is a Cerucal for injection. Ampoules are used both for intravenous and intramuscular administration.
The duration of the drug
The drug “Cerucal” in tablets reaches its maximum concentration in the blood an hour after administration. The effect of it remains for twelve hours. The maximum effect after intramuscular injection of the liquid form of the drug is observed half an hour after the injection. With intravenous injection, after 3 minutes.
What diseases should I take the medicine “Cerucal”
Vomiting and nausea of ​​any origin are the main indications for taking Cerucal. What else can this medicine help from? It is also worth taking, for example, with frequent constipation. In the event that you are sickness in a car or train, you can take a pill before the trip. In addition, this drug is prescribed for reflux esophagitis, biliary dyskinesia, and atony of the intestine and stomach.
How to use
With vomiting and nausea, on the recommendation of a doctor, the drug “Cerucal” should be taken an hour before meals. Instructions (the price of the drug is about 100 rubles in tablets) for use is extremely simple. Adults are usually recommended to take 3-4 tablets a day, one tablet. Adolescents from fourteen years old - half or a whole tablet 2-3 times a day. The drug is recommended to drink with water. This medicine can only be obtained by prescription. Most often, the course of treatment lasts a month and a half. But in some cases, this period can be up to six months.
Contraindications
About this drug there are, as already mentioned, very good reviews. Cerucal, however, is not recommended in some cases. You can not, for example, take pills and give injections in the first trimester of pregnancy. Subsequently, the drug should be taken with caution. Children under fourteen years of age cannot take this medicine in tablets. In addition, a contraindication may be:
- Pheochromocytoma.
- Perforation of the walls of the intestines and stomach.
- Bowel obstruction.
- Prolactin-dependent tumor.
- Pyloric stenosis .
- Epilepsy.
- Gastrointestinal bleeding.
- Extrapyramidal movement disorders.
- Intolerance to the individual components of the drug.
For children from two to fourteen years of age, the medicine “Cerucal” is prescribed only in the form of injections for the purpose of accurate dosing.
Side effects of the drug
Some patients give this medicine and not particularly good reviews. Cerucal, like most modern drugs, sometimes causes all sorts of unpleasant side reactions. In women, for example, the menstrual cycle may be disrupted. After taking a pill or injection, dry mouth often appears. In addition, this medicine may cause diarrhea or constipation. Some people taking the Cerucal preparation begin to experience dizziness or headaches. Anxiety, drowsiness, muscle spasms of the face, tinnitus, depression, parkinsonism are also related to the side effects of this medicine. In addition, the drug "Cerucal" can cause:
- Galactarea, gynecomastia.
- Hypotension or hypertension, as well as supraventricular tachycardia.
- Agranulocytosis.
- Itchy skin, urticaria, rash.
Other drug compatibility
The drug "Cerucal", the injection of which can stop vomiting, enhances the effects of alcohol and various kinds of psychotropic drugs. Do not take it at the same time as anticholinergics, as they can weaken the effect of metoclopramide. In addition, the medicine “Cerucal” enhances the absorption of various antibiotics. You can not take it simultaneously with antipsychotic drugs, since in this case the risk of extrapyramidal disorders increases.
The drug "Cerucal." Analogs
There are quite a large number of analogues of this drug. A similar antiemetic effect is exerted by Domstal, Domet, Motinor medicines, Metoclopramide, Damelium medicines, etc. Instead of the Cerucal preparation, one can take, for example, Itomed medicine. In addition to the antiemetic effect, this medication is able to eliminate heartburn. What medicine can the Cerucal drug be replaced with? Its analogs, such as, say, Motilak medicine, are also for the most part dispensed. Motilak medication helps with vomiting and nausea and relieves a symptom such as bloating. In addition, it helps with belching and heartburn. In the first trimester of pregnancy, as well as during lactation, it is possible to take it, unlike the preparation “Cerucal”, but only as prescribed by the doctor.
The medicine "Motilak" can cause skin itching and hives. In this, it is very similar to the Cerucal preparation, the analogues of which, with the same effect, can cost more or less. So, the medicine “Motilak” is sold in pharmacies for about 100-150 rubles. And the price of Itomed can reach up to 300 rubles.
Overdose Symptoms
In the case of the uncontrolled use of the drug “Cerucal”, unpleasant symptoms such as irritability, confusion, drowsiness, decreased or increased pressure, anxiety, bradycardia, motor disorders can occur. The effects of an overdose disappear about a day after the drug is discontinued. The patient in this period of time should be under the supervision of a doctor.
In the event that extrapyramidal disorders are observed, the doctor sometimes prescribes the drug "Biperiden". However, such an intervention can only be performed in a hospital setting. With the manifestation of such an overdose symptom as anxiety or irritability, the patient is prescribed the drug “Diazepam". In the event that the patient has taken too much Cerucal, gastric lavage is prescribed.
The drug "Cerucal", therefore, can be considered quite effective. However, taking it without a doctor’s appointment is by no means worth it.