In the article we will consider analogues of “Tiocetam” It belongs to the category of cerebroactive drugs that exhibit a nootropic, anti-ischemic and antioxidant property. The pharmacological effect of this drug is explained by the mutually potentiating effect of the substances thiotriazolin and piracetam.
Composition and format of the release of "Tiocetam"
This medicine is produced in tablets and solution. This is a combination remedy. The composition of "Tiocetam" contains the active ingredients in the form of piracetam and thiotriazoline. Next, find out when the use of the presented medication is appropriate for treatment.
Indications for use of "Tiocetam"
The medication in question is prescribed to patients in the following cases:
- Against the background of chronic brain ischemia.
- As part of the recovery period of ischemic stroke (in patients who have non-cement cognitive impairment, including).
- With diabetic encephalopathy.
How to use "Tiocetam" in ampoules? The instruction for use reports that the solution for parenteral administration is administered intravenously or intramuscularly, if it is not possible to use the oral form of the drug. For the treatment of ischemia, 20-30 ml are injected intravenously, previously the solution is diluted in 150 ml of sodium chloride. The average course of treatment is 14 days, then they start taking pills. If the patient has diabetic encephalopathy, then the solution is administered intramuscularly at 5 ml once a day, the course of therapy is up to 10 days.
List of analogues
Tiocetam has no structural analogues in terms of the active substance. Therefore, this nootropic medication is unique in its combination of the active components that make up its composition. Substitutes for the pharmacological group (category of nootropics) include: “Aminalon”, “Amilonosar” along with “Vinpotropil”, “Gammalon”, “Gliatilin”, “Glycine”, “Kombitropil”, “Lutsetam”, “Mexiprim”, “Noopept” ”,“ Noofen ”,“ Noocetam ”,“ Omaron ”,“ Piracetam ”,“ Pyriditolum ”,“ Semax ”,“ Ceraxon ”,“ Enerbol ”and others.
Now we will take a closer look at the most popular analogues of Tiocetam and find out under what indications they are prescribed to patients, as well as find out what their composition is.
Piracetam
"Piracetam" is a nootropic drug. By definition, they are called drugs that have an activating effect on the learning process. Such drugs improve memory with intellectual activity, as well as increase the resistance of the brain to aggressive effects. What helps Piracetam? The tool can positively affect blood circulation and metabolic processes in the brain.
The medicine manifests a pronounced nootropic activity, for example:
- It stimulates the integrative activity of the brain and intellectual function.
- The medicine strengthens the memory.
- Thanks to him, the learning process is facilitated.
- Using this analogue increases mental performance.
The main active ingredient of the drug is the eponymous ingredient piracetam. The composition of the auxiliary components depends on the format of the drug.
What helps Piracetam is interesting to many. The indication is the symptomatic treatment of psycho-organic syndromes, especially in elderly patients who suffer from decreased memory, dizziness, decreased concentration of attention and activity in general, and, in addition, behavior disorder and mood lability.
The medicine must be taken before meals inside. Adults take from 30 to 160 milligrams per kilogram of weight four times a day. The duration of therapy is six to eight weeks. If necessary, the drug is administered intravenously or intramuscularly at an initial dosage of 10 grams per day.
With intravenous administration to patients in serious condition, the daily norm can be 12 grams. After clinical improvement, the dosage is gradually reduced, and move on to internal administration. Children inside are prescribed 30 milligrams of the drug per kilogram of weight twice a day. Treatment is recommended to continue for at least three weeks.
Consider other analogues of "Tiocetam".
"Piracezin" in the form of tablets
Means "Piracezin" acts as a combination medicine, created on the basis of cinnarizine and piracetam. According to its manufacturer, the drug improves metabolism and blood circulation in the brain. In this regard, the medication is prescribed for stroke, encephalopathy, pathology of the nervous system, brain injury and some other diseases.
The medicine is produced in the form of gelatinous hard capsules having a cylindrical shape with hemispherical ends. Painted white, white powder inside. In one such pill is immediately two active ingredients, which are cinnarizine and piracetam. Additional components are calcium stearate and magnesium carbonate. The shell is prepared from gelatin, glycerol, water, sodium lauryl sulfate, nipazole and titanium dioxide.
Piracezin tablets are sold in blisters, for the manufacture of which aluminum foil and a polyvinyl chloride film are used. Blisters are packed in cardboard boxes. Indications for use of this analogue are the following pathologies and conditions:
- Comprehensive treatment of asthenia of a psychogenic type.
- Chronic cerebrovascular insufficiency.
- The presence of Meniere's syndrome.
- Pathologies of the nervous system, in which a decrease in intellectual and mnestic functions is observed.
- The development of labyrinthopathy.
- Psycho-organic syndrome with signs of asthenia and adynamia.
- Prevention of kinetosis and migraine.
The considered analog is administered orally one, two or three capsules three times a day. Do this after eating or during a meal. The duration of treatment varies from one to three months. The maximum number of capsules that can be taken in one day is six. In the event that the patient has chronic kidney failure, the dosage is reduced. An alternative is to increase the interval between doses.
Analogues of "Tiocetam" in Russia can be purchased at any pharmacy.
Thiotriazolinum
This drug improves metabolic processes. It differs in anti-ischemic, membrane-stabilizing, antioxidant, immunomodulatory effects. The influence of the active ingredient is realized by increasing the compensatory activation of anaerobic glycolysis and the activation of oxidation processes in the cell. It inhibits the oxidation of fats in ischemic areas of the heart muscle, reduces its sensitivity to catecholamines, preventing the progression of contractile functions of the heart and reducing the area of myocardial necrosis. The active substance of this substitute are the morpholine salts of thiazoic acid. This medicine is used in a number of the following cases:
- As part of the comprehensive treatment of coronary disease, for example, with myocardial infarction, the development of angina pectoris, cardiosclerosis and so on.
- For the treatment of cardiac arrhythmias.
- Treatment of chronic hepatitis (cryptogenic, alcoholic), fibrosis and cirrhosis of the liver.
The medicine "Thiotriazolinum" is applied inside. The standard dose for stable exertional angina in a patient is 200 milligrams three times a day. The course is eight weeks. In case of myocardial infarction, exactly, as against the background of rest angina pectoris or post-infarction cardiosclerosis, 200 milligrams should be used three times within twenty or thirty days.
The dose for heart rhythm disturbance is 200 milligrams under the tongue three times a day. In case of liver disease, the same dosage is taken for twenty to thirty days. The duration of the course is usually individual and depends on the severity of the disease. The side reactions that occur when using this analogue are the following reactions:
- Cardiovascular disorder in the form of increased pressure, palpitation, tachycardia.
- Neurological disorder in the form of headaches, tinnitus, dizziness, impaired coordination.
- Digestive abnormalities, for example, dry mouth combined with nausea, flatulence, dyspepsia.
- Immune disorders include rashes, hives, angioedema.
- Other reactions may include suffocation along with shortness of breath, fever, and weakness.
Description of "Glycine"
A popular substitute for Tiocetam is the drug Glycine. The active substance in this case is an aliphatic amino acid (it is also called aminoacetic). They release it in sublingual tablets of 100 milligrams.
“Glycine” is a medicine that affects metabolism. This amino acid in the composition of the “Glycine” tablets serves as a metabolic regulator, can activate the process of protective inhibition in the brain, reduces emotional stress, stimulating mental performance. In addition, the drug has an adrenergic blocking, antitoxic (eliminates the effects of poisoning), antioxidant property. It regulates the activity of glutamate receptors, so the effect of taking the drug may be as follows:
- Reducing the psycho-emotional stress of a person.
- Decreased conflict and aggressiveness, increased social adaptation.
- Improving mood, greatly facilitating falling asleep along with normalizing sleep patterns.
- A marked increase in mental performance.
- Elimination or reduction of existing autonomic vascular disorders (including symptoms of menopause).
- Reducing the severity of cerebral disorders in brain injury, stroke.
- Reducing the toxic effects of alcohol and some drugs that inhibit the nervous system.
Amino acetic acid reduces the severity of adverse reactions from the use of antipsychotics (i.e. antipsychotics), antidepressants, sleeping pills, anticonvulsants. Such an acid can easily penetrate various tissues and body fluids. It decomposes, as a rule, to water and carbon dioxide, while its accumulation does not occur.
Lucetam tablets: indications
“Lucetam" is a drug with nootropic effects. Indications for use are as follows:
- In the presence of consequences of ischemic stroke, including impaired motor and mental activity, emotional sphere and speech.
- In the case of the development of a psycho-organic syndrome (especially in elderly patients), which is accompanied by dizziness, decreased memory, behavioral disorders, mood changes, decreased concentration of attention and activity, impaired gait, and, in addition, with the occurrence of Alzheimer's pathology and senile type of Alzheimer's dementia (in this case, symptomatic treatment is performed).
- When dizziness and related imbalances occur, in addition to the mental nature of the deviation.
- Against the background of chronic alcoholism (treatment of psycho-organic and withdrawal syndromes).
- As part of the recovery period after intoxication and brain injury.
- With cortical myoclonia (as monotherapy or simultaneously with other drugs).
- In the case of low learning ability in children, especially during the period of obtaining a specific skill in counting, reading and writing, which cannot be explained by the family situation, inadequate instruction, or mental retardation (can be used simultaneously with other medications).
“Lucetam” is taken orally, it is washed down with liquid (water or juice). The tool should be consumed on an empty stomach or during a meal. The injection solution is administered intravenously or intramuscularly.
Aminalon
This analogue, as a rule, is used as part of complex therapy of diseases of the nervous system. Indications for the appointment of the medication are as follows:
- The presence of vascular diseases of the brain, for example, in the form of atherosclerosis, vascular lesions with the development of arterial hypertension.
- Chronic cerebrovascular insufficiency with impaired memory and attention in patients.
- With problems with speech, and, in addition, against the background of dizziness, headaches.
- In the case of the development of encephalopathy (alcoholic, post-stroke, post-traumatic).
- Against the background of cerebral palsy.
- In the case of mental retardation in children aged five years.
- Against the background of senile dementia (that is, the initial stages of dementia).
- In case of sea or air sickness (in order to prevent and treat the symptoms of motion sickness).
Finally
Thus, there are many drugs that can serve as a substitute if necessary. As for the drug itself, it is worth bearing in mind that with prolonged treatment with it, elderly patients are advised to regularly monitor the condition of the kidneys. It should also be borne in mind that during treatment with this tool, exactly like its analogues, it is required to refrain from driving vehicles.
We examined analogues and instructions for use with “Tiocetam” in ampoules and tablets.