Movinase tablets, the instructions for use describe in detail the doses and the method of taking the drug, have the ability to penetrate into the inflamed areas of tissues, lyse dead cells, as well as their decomposition products. Reduce hyperemia and increase the effect of antibiotics. The drug reduces the viscosity of saliva and reduces discharge from the nasal cavity.
Composition and form of release of the drug
Before using the Movinase tablets, the instructions for use must be studied. The drug contains the active substance - serratiopeptidase.
It is produced in tablets with enteric-soluble shells of 10 and 20 mg, which are packaged in aluminum blisters of ten pieces. The cardboard box contains thirty tablets and instructions.
Pharmacological action of the drug
The medicine "Movinase" (instructions for use is attached to the tablets) is a proteolytic enzyme obtained from the bacterium Serratia E15, which is located in the human intestine. It has a fibrinolytic, decongestant and anti-inflammatory property. Not only reduces inflammation, but also reduces the severity of pain, inhibits and releases amines of pain from tissues that are inflamed.
Serratiopeptidase combines in a 1: 1 ratio with α-2-macroglobulin in the blood and masks their antigenicity, but at the same time continues to maintain enzymatic activity. The active substance gradually passes into exudate at the site of the inflammatory process, lowering its level in the blood. Reduces the dilatation of capillaries, controls by hydrolysis of serotonin, histamine and bradykinin. It inhibits plasmin inhibitors, develops fibrinolytic activity. Due to proteolysis of sputum proteins, it restores rheological qualities, which contributes to its rapid discharge.
The enzymatic activity of the drug is ten times greater than that of α-chymotrypsin. In the area of chronic inflammation, the active substance reduces the rate of mediators of inflammation and pain, hydrolyzes fibrin, prevents adhesions from forming, reduces microcirculation in the focus of inflammation, due to increased bioavailability of drugs.
“Movinase” does not affect animal protein, such as albumin, α- and γ-globulin. The medicine does not break down fibrinogen and, therefore, does not affect blood coagulation.
In general, Movinase reduces the inflammatory nature of tissues, reduces edema, and increases the effect of NSAIDs and antibiotics. It has an enteric-soluble membrane with a high degree of protection.
The medicine passes through the gastric organ in an unchanged form and is absorbed in the intestinal environment. The maximum concentration of the active substance in the blood is reached in an hour. It leaves the body with bile, and a small part with urine.
Indications for use
The drug "Movinase" (instructions for use strongly advises you to consult a doctor before using tablets) is used in surgery. Here it is used for sprain and rupture of ligaments, as well as for fractures and dislocations. It treats swelling that occurs after surgery.
Prescribe a medicine for diseases of the upper respiratory tract. It reduces the viscosity of sputum and contributes to its rapid discharge. Doctors prescribe the drug for ENT diseases to more effectively get rid of the secretion from the sinuses. Indications for use are acute dermatoses with inflammatory foci. A drug is used in obstetrics and gynecology for the treatment of hematomas and the elimination of stagnation in the mammary glands.
"Movinase-20": instructions for use
The tablets are taken orally. They are drunk without chewing, washed down with water.
"Movinase-10" (instructions for use warns of contraindications and possible side effects) are prescribed to adults in a dosage of 10-20 mg once a day after meals. The maximum daily dosage should not exceed a dose of 30 mg.
The duration of the course of taking the tablets is regulated by the doctor, depending on the condition of the patient and the course of the disease.
Contraindications
Means "Movinase" (20 mg), instructions for use introduces the rules of storage of the drug, despite its effectiveness, has contraindications. These include hypersensitivity to serratiopeptidase and additional components of the drug. A ban on use are diseases associated with poor blood coagulation.
In some cases, when using the drug, patients were worried about side effects. Among them are vomiting, diarrhea, anorexia, nausea, discomfort in the epigastric zone. Sometimes there was bleeding from the nose, the appearance of sputum with blood, allergies, rash, eosinophilic pneumonia in the acute stage.
If there are negative reactions, then the medication should be stopped and consult your doctor to review the therapeutic appointment.
special instructions
Warns that it affects the blood coagulability of the tablets "Movinase", instructions for use. Reviews say that the drug is highly effective and quickly relieves swelling and inflammation. It should be taken with extreme caution by patients with an increased risk of bleeding and persons who have problems with blood coagulation and who use anticoagulants.
The drug should be prescribed with extreme caution to patients with liver and kidney diseases.
Do not drink tablets for pregnant and lactating women, since there are no clinical data on the use of the drug during this period.
You can not give tablets to children, since there is no data on the safety and effectiveness of the drug in this category of patients.
"Movinase" does not affect the ability to make decisions and the speed of reaction when driving a car and similar vehicles that require increased concentration of attention.
Joint use with anticoagulants increases the effect of the latter on the body. Promotes faster penetration of antibiotics and NSAIDs into the inflamed environment.
In case of an overdose, nausea, anorexia, vomiting, bleeding, blood in the sputum is observed.
Advises only symptomatic treatment in case of overdose with the drug "Movinase" instructions for use.
Analogs
If the drug caused negative phenomena, then it can be replaced by another with a similar effect. So, the direct analogues of "Movinase" include "Serox" and "Serrata". Medicines with a similar effect, but containing another active substance, should include: “Wobenzym”, “Fibrinase-10”, “Fibrinase-20”, “Flogenzim”.