"Nexavar" is an antitumor drug. Its therapeutic effect is the inhibition of kinase enzymes, the action of which provokes the growth of low-quality neoplasms. The active substance of the drug is sorafenib, auxiliary substances - croscarmellose sodium, MCC, hypromellose, magnesium stearate and sodium lauryl sulfate.
The drug has proven itself in the treatment of hepatocellular and renal cell carcinoma, and doctors note that the prognosis of survival in patients is higher if the drug Nexavar is used in the treatment regimen. Patient reviews are also positive. Inhibition of growth of the neoplasm is noted, the patient's well-being also improves. That is why the drug "Nexavar" is used in more than 100 countries.
Nexavar: the original drug and generics
Generic is a drug with a similar composition, only auxiliary components can differ. The fact that such drugs are significantly cheaper does not mean that they are worse. It’s just that during their production, the manufacturer does not develop a drug formula from scratch, does not conduct large-scale tests, does not invest in an advertising campaign. Due to this, the price of the drug is much lower.
It should be noted that the drug has two generics - Sorafenat and Soranib. The active substance in them is the same as in the original preparation, but the additional components of the composition are slightly different. Next, talking about the tool , its contraindications and method of application, we will describe the generics mentioned.
Where to buy generic "Nexavar"
The original drug is made in Germany and has a fairly high cost. In Russian pharmacies, it can be found at prices ranging from 69 to 165 thousand rubles. This cost of one package of the product is affordable, and therefore many people prefer to buy generics of Nexavar. The price is significantly lower - from 6500 rubles to 23 000. The cost depends on the number of tablets in the package.
You can buy Sorafenat and Soranib on a special website . This is the site of a large Indian company that has been successfully operating in the global market for 5 years. When contacting the company's specialists, prepare in advance all the documents confirming the need to purchase the funds.
"Nexavar": instructions for use
The drug is administered orally. The recommended daily dose is 800 mg. You can take "Nexavar" on an empty stomach and with food, but in the second case, you need to make sure that the dishes are not fatty (this reduces the bioavailability of the active substance).
Observe the body's response to the drug. If there is a pronounced toxic effect, the drug should be discontinued. In addition, in the absence of improvement, Nexavar is also excluded from the treatment regimen.
Contraindications
The drug is contraindicated in the following cases:
- individual intolerance to the components of the composition;
- pregnancy and breastfeeding;
- childhood.
Side effects
The use of Nexavar can cause the following negative reactions of the body:
- anemia;
- increase in blood pressure;
- internal bleeding;
- diarrhea, nausea, and vomiting;
- skin rash;
- renal failure;
- erectile disfunction;
- depression.
special instructions
Therapy with the use of the drug "Nexavar" should be carried out only under the supervision of an experienced doctor. He will study all the features of the patient’s condition and will monitor peripheral blood counts.
With drugs such as Irinotecan and Docetaxel, Nexavar and its generics should be used with caution.