Often our liver needs extra support. This is especially necessary for a number of pathologies affecting the cells of this organ, as well as when taking certain medications. Special medicines called hepatoprotectors will help protect the liver. Among them, Progepar is quite popular and receives good reviews. What is this drug and does it have analogues?
Composition and action
The basis of the drug is cyanocobalamin, inositol, cysteine and choline bitartrate, which have beneficial effects on liver cells. They increase the regenerative ability of hepatocytes, maintaining their viability. As a result of the reduction in the intensity of death of liver cells, the synthetic potential of fibroblasts decreases - the processes of cirrhosis and sclerosis slow down, that is, the replacement of the parenchyma with a functionally inactive connective tissue. This is the prevention of the development of chronic liver failure. Additionally, the blood circulation of the liver improves, which prevents hypoxia and necrosis as a result of this. This effect gives the drug "Progepar". Use should be monitored by a physician.
When is the drug prescribed?
"Progepar" is necessary for diseases and conditions when there is damage to the liver parenchyma or an increased load on the organ. Among the factors requiring the use of hepatoprotectors, we can distinguish:
- cirrhosis of the liver (to slow down the course of the disease);
- hepatopathy;
- chronic hepatitis - alcoholic, viral, medicinal;
- drug intoxication;
- radiation sickness ;
- psoriasis;
- treatment with cytostatics.
Contraindications
As a rule, hepatoprotectors are well tolerated by patients, since they practically have no restrictions on use. An absolute contraindication is hypersensitivity. It can lead to skin rashes, itching, and hyperemia (an allergic reaction). In addition, the drug is not used in childhood and during pregnancy. These are the features of Progepar, analogues have fewer contraindications.
Instruction manual
"Progepar" is taken enterally, that is, inside. Release form - tablets. As a rule, 1-2 pieces are prescribed 3 times a day, however, the treatment regimen can be adjusted by the attending physician. Depending on the pathology, the duration of therapy with Progepar is determined. Price - 1700-2000 rubles per 100 tablets.
Reviews "Progepar"
The medicine is required to treat liver diseases characterized by the death of hepatocytes. Diagnostic studies of patients taking Progepar for a long time show a slowdown in the processes of sclerosis of the liver parenchyma. This helps maintain its function and increase the life expectancy of the patient. It should be noted that the effect is observed only with complex treatment. The choice of therapeutic measures depends on the disease and the individual characteristics of the patients.
Those who were treated with this drug note its effectiveness. After taking, many have stabilized indicators of the diagnosis of liver function, and the general condition has improved. The negative point for most consumers is the high price. This is noted in almost all reviews.
"Progepar" - analogues
Among the hepatoprotectors, there are other drugs that have a similar mechanism of action with Progepar. Replacement with an analog is allowed only with the permission of a specialist. Medicines that help protect the liver may differ in the active substance, the features of use, but their main goal is to prevent the death of hepatocytes.
Silimar
The medicine is of plant origin - the active substance is milk thistle fruit extract. This component of the drug affects the metabolism of hepatocytes, stabilizing their membranes (toxins lose access to the cell) and reducing the activity of dystrophic phenomena. The peculiarity is that Silimar can be used in childhood. Usually 1-2 tablets are used per day, and the course of such treatment is 1 month. If necessary, repeat the therapy. Among the side effects, only allergic reactions in the form of skin rashes are possible. Thus, the drug is safer than Progepar, but its effectiveness is slightly lower. In severe pathologies accompanied by intense sclerosis, it is better to give preference to a stronger drug. The price of the drug is 100-150 rubles. The drug due to safety receives positive reviews. "Progepar" has more contraindications.
Heptral
The drug additionally has a detoxifying and antioxidant effect. The active substance (ademethionine) affects the synthesis of phospholipids, which are a component of membranes. Among the contraindications are not only hypersensitivity and the age of up to 18 years. The drug is not prescribed if there are any genetic disorders that affect the methionine cycle. The full use of the drug is allowed in the 3rd trimester of pregnancy, since no pathological effect on the fetus has been established. For the rest of the gestation period, as well as during lactation, the drug is better not to kick. Therapy is possible only with strict indications. The price is 1500-1700 rubles.
Hepatoprotectors are a component of complex therapy for liver diseases. They help protect hepatocytes and stimulate regeneration. The choice of drug and dosage is carried out by the attending physician. More often, doctors prescribe based on survey data and reviews.
“Progepar”, along with its counterparts, performs a very important job - it stabilizes the functioning of the liver.