The drug "Azithromycin 250 mg" is included in the category of antibiotics with a wide spectrum of activity from the subgroup of azalides in the macrolide group. High concentrations of the active ingredient in the focus of inflammation have a bactericidal effect. Compared with other drugs of the macrolide group, Azithromycin (for children and adults) has a more pronounced bactericidal effect, the ability to penetrate into fluids, cells, body tissues, and a longer half-life. Clinical effectiveness is usually achieved within a three-day course. The medicine affects a number of gram-negative, gram-positive bacteria.
Description
The medication, when administered orally, is absorbed quite well. After ingestion, a fairly rapid distribution of it in the tissues occurs. Moreover, the concentration in them is many times higher than the plasma level. Due to the ability of the active component to accumulate in white blood cells, increased antimicrobial activity is provided. With cells, the drug is transported to inflammatory foci. As a result, the concentration in these areas is six times higher than in intact tissues. Withdrawal of the antibiotic is carried out slowly from the body. This allows you to take it once a day, reduce the duration of therapy to five days. A high level in the tissues remains for about seven days after the end of treatment.
Indications. Contraindications
The drug "Azithromycin" for children and adults is prescribed for infections provoked by sensitive bacteria. Indications include, in particular, skin pathologies, lesions of subcutaneous fat (dermatoses (second-infected), impetigo, erysipelas). The medication is recommended for infections in the genitals and urinary tract (gonococcal or acute nonspecific (chlamydial) urethritis, colpitis, cervicitis). Respiratory diseases in children and adults are also indications for the use of the drug. The medication is recommended for acute bronchitis, tonsillitis, pharyngitis, scarlet fever, pneumonia, otitis media. No agent is prescribed in the presence of hypersensitivity to the components.
Mode of application
The medicine "Azithromycin" for children over one year old is allowed to be prescribed. Recommended use: on the first day, 10 mg per kg of body weight, in the next 4 days, five milligrams per kilogram once a day. The drug is taken an hour before meals or after two hours later. In case of respiratory infections, adults are prescribed five hundred milligrams at a time, from the second to the fifth day, the dosage is halved. With sexual pathologies, the drug is prescribed once. It should be noted that due to the pharmacokinetic properties of the drug "Azithromycin" for children and adults, you can take a short time - a maximum of seven days. Very rarely, longer therapy may be required in combination with various antimicrobials. In some cases, the doctor may recommend a combination with immunomodulatory drugs.